Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemia but not insulin resistance in mice with diet-induced obesity

Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening

(2010) Haiyan Cai et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

RNAi-mediated germline knockdown of FABP4 increases body weight but does not improve the deranged nutrient metabolism of diet-induced obese mice

(2010) R Yang et al.   INTERNATIONAL JOURNAL OF OBESITY

N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors

(2009) Tjeerd Barf et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

(2009) K Takashima et al.   BRITISH JOURNAL OF PHARMACOLOGY

Interaction of Adipocyte Fatty Acid-binding Protein (AFABP) and JAK2

(2009) Brian R. Thompson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of a Small Molecule Inhibitor of Fatty Acid Binding Proteins

(2009) Ann V. Hertzel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Increasing the length of progerin's isoprenyl anchor does not worsen bone disease or survival in mice with Hutchinson-Gilford progeria syndrome

(2008) Brandon S. J. Davies et al.   JOURNAL OF LIPID RESEARCH

Fatty acid-binding proteins: role in metabolic diseases and potential as drug targets

(2008) Masato Furuhashi et al.   NATURE REVIEWS DRUG DISCOVERY