Mechanoimmunology: molecular-scale forces govern immune cell functions
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Title
Mechanoimmunology: molecular-scale forces govern immune cell functions
Authors
Keywords
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Journal
MOLECULAR BIOLOGY OF THE CELL
Volume 29, Issue 16, Pages 1919-1926
Publisher
American Society for Cell Biology (ASCB)
Online
2018-08-08
DOI
10.1091/mbc.e18-02-0120
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Note: Only part of the references are listed.- Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms
- (2018) Tsung-Li Liu et al. SCIENCE
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- (2017) Yunfeng Chen et al. MOLECULAR BIOLOGY OF THE CELL
- Mechanosensing drives acuity ofαβT-cell recognition
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- (2016) Luís C Santos et al. IMMUNOLOGY AND CELL BIOLOGY
- Pre-T Cell Receptors (Pre-TCRs) Leverage Vβ Complementarity Determining Regions (CDRs) and Hydrophobic Patch in Mechanosensing Thymic Self-ligands
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- (2016) Sophie V. Pageon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrins outside focal adhesions transmit tensions during stable cell adhesion
- (2016) Yongliang Wang et al. Scientific Reports
- The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling
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- (2014) Baoyu Liu et al. CELL
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- (2014) Marcia A Munoz et al. CURRENT OPINION IN CELL BIOLOGY
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- (2014) S. Pryshchep et al. JOURNAL OF IMMUNOLOGY
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- (2013) Pieta K. Mattila et al. IMMUNITY
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- (2013) E. Natkanski et al. SCIENCE
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- (2013) S. V. Pageon et al. Science Signaling
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- (2013) Jens Möller et al. Scientific Reports
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- (2012) Edward Judokusumo et al. BIOPHYSICAL JOURNAL
- The structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function
- (2012) Jia-huai Wang et al. IMMUNOLOGICAL REVIEWS
- Student award winner in the undergraduate category for the society of biomaterials 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012
- (2012) Anna K. Blakney et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Substrate Rigidity Regulates Human T Cell Activation and Proliferation
- (2012) R. S. O'Connor et al. JOURNAL OF IMMUNOLOGY
- Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells
- (2012) Jason Yi et al. MOLECULAR BIOLOGY OF THE CELL
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- (2012) Raquel Blanco et al. Frontiers in Immunology
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- (2011) V. Swaminathan et al. CANCER RESEARCH
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- (2011) T. S. Lim et al. JOURNAL OF IMMUNOLOGY
- Activation of the innate immune receptor Dectin-1 upon formation of a ‘phagocytic synapse’
- (2011) Helen S. Goodridge et al. NATURE
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- (2011) Daniel R Stabley et al. NATURE METHODS
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- (2011) Julien Husson et al. PLoS One
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- (2011) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Atomic force microscopy: a nanoscopic window on the cell surface
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- The αβ T Cell Receptor Is an Anisotropic Mechanosensor
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- Cooperativity Between T Cell Receptor Complexes Revealed by Conformational Mutants of CD3
- (2009) N. Martinez-Martin et al. Science Signaling
- T cell receptor triggering by force
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- (2008) Christine Gourier et al. Cellular and Molecular Bioengineering
- Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy
- (2008) Keir C Neuman et al. NATURE METHODS
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