B cell antigen extraction is regulated by physical properties of antigen-presenting cells

Germinal center B cells recognize antigen through a specialized immune synapse architecture

(2016) Carla R Nowosad et al.   NATURE IMMUNOLOGY

Supramolecular peptide vaccines: tuning adaptive immunity

(2015) Yi Wen et al.   CURRENT OPINION IN IMMUNOLOGY

Polarity protein Par3 controls B-cell receptor dynamics and antigen extraction at the immune synapse

(2015) Anne Reversat et al.   MOLECULAR BIOLOGY OF THE CELL

The activation of IgM- or isotype-switched IgG- and IgE-BCR exhibits distinct mechanical force sensitivity and threshold

(2015) Zhengpeng Wan et al.   eLife

DNA-based digital tension probes reveal integrin forces during early cell adhesion

(2014) Yun Zhang et al.   Nature Communications

Determinants of Maximal Force Transmission in a Motor-Clutch Model of Cell Traction in a Compliant Microenvironment

(2013) Benjamin L. Bangasser et al.   BIOPHYSICAL JOURNAL

Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation

(2013) Balthasar A. Heesters et al.   IMMUNITY

Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4+T-cell activation

(2013) Marzena Ciechomska et al.   IMMUNOLOGY

Biofilm Matrix Exoproteins Induce a Protective Immune Response against Staphylococcus aureus Biofilm Infection

(2013) Carmen Gil et al.   INFECTION AND IMMUNITY

Germinal center B cells govern their own fate via antibody feedback

(2013) Yang Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

B Cell Activation Is Regulated by the Stiffness Properties of the Substrate Presenting the Antigens

(2013) Z. Wan et al.   JOURNAL OF IMMUNOLOGY

B Cells Use Mechanical Energy to Discriminate Antigen Affinities

(2013) E. Natkanski et al.   SCIENCE

Defining Single Molecular Forces Required to Activate Integrin and Notch Signaling

(2013) X. Wang et al.   SCIENCE

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

Polarized Secretion of Lysosomes at the B Cell Synapse Couples Antigen Extraction to Processing and Presentation

(2011) Maria-Isabel Yuseff et al.   IMMUNITY

A dynamic T cell–limited checkpoint regulates affinity-dependent B cell entry into the germinal center

(2011) Tanja A. Schwickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells

(2010) H. Li et al.   BLOOD

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

(2010) Santiago F Gonzalez et al.   NATURE IMMUNOLOGY

Visualizing B cell capture of cognate antigen from follicular dendritic cells

(2009) Kazuhiro Suzuki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Force probing surfaces of living cells to molecular resolution

(2009) Daniel J Müller et al.   Nature Chemical Biology