Poly(ADP-ribose) Polymerase 1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Implications
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Poly(ADP-ribose) Polymerase 1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Implications
Authors
Keywords
-
Journal
MEDICINAL RESEARCH REVIEWS
Volume 34, Issue 3, Pages 644-675
Publisher
Wiley
Online
2013-09-04
DOI
10.1002/med.21300
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging
- (2016) Matthias Altmeyer et al. Aging-US
- Interference between PARPs and SIRT1: a novel approach to healthy ageing?
- (2016) Carles Cantó et al. Aging-US
- Poly(ADP-ribose) polymerase-1-induced NAD+ depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation
- (2013) Tiina M. Kauppinen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Enhanced NF- B Activity Impairs Vascular Function Through PARP-1-, SP-1-, and COX-2-Dependent Mechanisms in Type 2 Diabetes
- (2013) M. Kassan et al. DIABETES
- Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease
- (2013) Reza Sharifi et al. EMBO JOURNAL
- PARP inhibitors: polypharmacology versus selective inhibition
- (2013) Torun Ekblad et al. FEBS Journal
- Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes
- (2013) Carles Cantó et al. MOLECULAR ASPECTS OF MEDICINE
- Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases
- (2013) Florian Rosenthal et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A family of macrodomain proteins reverses cellular mono-ADP-ribosylation
- (2013) Gytis Jankevicius et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Identification of Pim Kinases as Novel Targets for PJ34 with Confounding Effects in PARP Biology
- (2012) Albert A. Antolín et al. ACS Chemical Biology
- Poly(ADP-ribose) polymerase 1 inhibition protects human aortic endothelial cells against LPS-induced inflammation response
- (2012) X. Peng et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Inflammation in Atherosclerosis
- (2012) Peter Libby ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art
- (2012) Mike De Vos et al. BIOCHEMICAL PHARMACOLOGY
- Poly(ADP-ribose) polymerase inhibition prevents reactive oxygen species induced inhibition of aldehyde dehydrogenase2 activity
- (2012) Shu-jian Wei et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Poly(ADP-ribose) polymerase 1 inhibition protects against low shear stress induced inflammation
- (2012) Wei-dong Qin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
- (2012) Carles Cantó et al. Cell Metabolism
- The Role of PARP-1 and PARP-2 Enzymes in Metabolic Regulation and Disease
- (2012) Péter Bai et al. Cell Metabolism
- Poly(ADP-ribose) polymerase-2: emerging transcriptional roles of a DNA-repair protein
- (2012) Magdolna Szántó et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- LOX-1 in atherosclerosis: biological functions and pharmacological modifiers
- (2012) Suowen Xu et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Vascular Smooth Muscle Cell Sirtuin 1 Protects Against DNA Damage and Inhibits Atherosclerosis
- (2012) Isabelle Gorenne et al. CIRCULATION
- SIRT1: new avenues of discovery for disorders of oxidative stress
- (2012) Zhao Zhong Chong et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Role of poly(ADP-ribose) polymerases in the regulation of inflammatory processes
- (2012) Péter Bai et al. FEBS LETTERS
- Seven sirtuins for seven deadly diseases ofaging
- (2012) Brian J. Morris FREE RADICAL BIOLOGY AND MEDICINE
- Poly(ADP-Ribose) Polymerase 1 Inhibition Improves Coronary Arteriole Function in Type 2 Diabetes Mellitus
- (2012) Soo-Kyoung Choi et al. HYPERTENSION
- Poly (ADP-ribose) polymerase 14 and its enzyme activity regulates TH2 differentiation and allergic airway disease
- (2012) Purvi Mehrotra et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Inflammasome-Activated Caspase 7 Cleaves PARP1 to Enhance the Expression of a Subset of NF-κB Target Genes
- (2012) Süheda Erener et al. MOLECULAR CELL
- Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors
- (2012) Elisabet Wahlberg et al. NATURE BIOTECHNOLOGY
- Reanalysis of phosphoproteomics data uncovers ADP-ribosylation sites
- (2012) Ivan Matic et al. NATURE METHODS
- Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress
- (2012) Jean-Philippe Gagné et al. NUCLEIC ACIDS RESEARCH
- Negative regulation of inflammation by SIRT1
- (2012) Jun Xie et al. PHARMACOLOGICAL RESEARCH
- Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
- (2012) Ruben Nogueiras et al. PHYSIOLOGICAL REVIEWS
- Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue
- (2012) Hassina Massudi et al. PLoS One
- Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1
- (2012) M.-F. Langelier et al. SCIENCE
- Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation
- (2012) Suowen Xu et al. Translational Research
- Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in Apolipoprotein-E knockout mice fed a high cholesterol diet
- (2011) Suowen Xu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Minocycline reduces plaque size in diet induced atherosclerosis via p27Kip1
- (2011) Khurrum Shahzad et al. ATHEROSCLEROSIS
- Poly(ADP-ribose) polymerase-2 depletion reduces doxorubicin-induced damage through SIRT1 induction
- (2011) Magdolna Szántó et al. CARDIOVASCULAR RESEARCH
- Loss of Tankyrase-Mediated Destruction of 3BP2 Is the Underlying Pathogenic Mechanism of Cherubism
- (2011) Noam Levaot et al. CELL
- Crosstalk between Components of Circadian and Metabolic Cycles in Mammals
- (2011) Gad Asher et al. Cell Metabolism
- PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure
- (2011) Péter Bai et al. Cell Metabolism
- PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation
- (2011) Péter Bai et al. Cell Metabolism
- The Emerging Role of Poly(ADP-Ribose) Polymerase Inhibitors in Cancer Treatment
- (2011) Shahneen K. Sandhu et al. CURRENT DRUG TARGETS
- Mass spectrometry-based functional proteomics of poly(ADP-ribose) polymerase-1
- (2011) Emilie Pic et al. Expert Review of Proteomics
- Poly (ADP-Ribose) Polymerase Inhibition Attenuates Atherosclerotic Plaque Development in ApoE-/- Mice with Hyperhomocysteinemia
- (2011) Jiang-jiao Xie et al. Journal of Atherosclerosis and Thrombosis
- Sirtuins at a glance
- (2011) T. Nakagawa et al. JOURNAL OF CELL SCIENCE
- Glucagon-like peptide 1 protects microvascular endothelial cells by inactivating the PARP-1/iNOS/NO pathway
- (2011) Fu-qiang Liu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Sirtuins, Aging, and Medicine
- (2011) Leonard Guarente NEW ENGLAND JOURNAL OF MEDICINE
- Non-antibacterial tetracyclines modulate mediators of periodontitis and atherosclerotic cardiovascular disease: A mechanistic link between local and systemic inflammation
- (2011) Ying Gu et al. PHARMACOLOGICAL RESEARCH
- Matrix metalloproteinase inhibition with tetracyclines for the treatment of coronary artery disease
- (2011) Travis J. Bench et al. PHARMACOLOGICAL RESEARCH
- Cellular and cytokine-based inflammatory processes as novel therapeutic targets for the prevention and treatment of atherosclerosis
- (2011) Peter J. Little et al. PHARMACOLOGY & THERAPEUTICS
- Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats
- (2011) Nady Braidy et al. PLoS One
- Poly(ADP-ribose) Polymerase 1 Is Indispensable for Transforming Growth Factor-β Induced Smad3 Activation in Vascular Smooth Muscle Cell
- (2011) Dan Huang et al. PLoS One
- Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1-Dependent Cell Death (Parthanatos)
- (2011) Y. Wang et al. Science Signaling
- The potential for poly (ADP-ribose) polymerase inhibitors in cancer therapy
- (2011) M. Javle et al. Therapeutic Advances in Medical Oncology
- Preventing NAD+ Depletion Protects Neurons against Excitotoxicity
- (2010) Dong Liu et al. Annals of the New York Academy of Sciences
- Regulation of SIRT1 in cellular functions: Role of polyphenols
- (2010) Sangwoon Chung et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- iNOS induction and PARP-1 activation in human atherosclerotic lesions: an immunohistochemical and ultrastructural approach
- (2010) Ida Perrotta et al. CARDIOVASCULAR PATHOLOGY
- Opposing roles of PARP-1 in MMP-9 and TIMP-2 expression and mast cell degranulation in dyslipidemic dilated cardiomyopathy
- (2010) Chetan P. Hans et al. CARDIOVASCULAR PATHOLOGY
- Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle
- (2010) Carles Cantó et al. Cell Metabolism
- The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
- (2010) Riekelt H. Houtkooper et al. ENDOCRINE REVIEWS
- SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis
- (2010) Sokrates Stein et al. EUROPEAN HEART JOURNAL
- Serum or target deprivation-induced neuronal death causes oxidative neuronal accumulation of Zn2+ and loss of NAD+
- (2010) Christian T. Sheline et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP
- (2010) A. K. Walker et al. GENES & DEVELOPMENT
- Mechanical stretch enhances NF- B-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells
- (2010) T. Morisugi et al. JOURNAL OF BIOCHEMISTRY
- Identification of the Aryl Hydrocarbon Receptor Target GeneTiPARPas a Mediator of Suppression of Hepatic Gluconeogenesis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin and of Nicotinamide as a Corrective Agent for This Effect
- (2010) Silvia Diani-Moore et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SIRT1 Deacetylates and Inhibits SREBP-1C Activity in Regulation of Hepatic Lipid Metabolism
- (2010) Bhaskar Ponugoti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PARP-14 Functions as a Transcriptional Switch for Stat6-dependent Gene Activation
- (2010) Purvi Mehrotra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Poly(ADP-Ribose) Polymerase-1 Is a Determining Factor in Crm1-Mediated Nuclear Export and Retention of p65 NF- B upon TLR4 Stimulation
- (2010) M. Zerfaoui et al. JOURNAL OF IMMUNOLOGY
- Genetic Ablation of PARP-1 Protects Against Oxazolone-Induced Contact Hypersensitivity by Modulating Oxidative Stress
- (2010) Attila Brunyánszki et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Effect of an Antimicrobial Agent on Atherosclerotic Plaques
- (2010) Satoru Ohshima et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
- (2010) Aswin Mangerich et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry
- (2010) Maxim Isabelle et al. Proteome Science
- Toward a unified nomenclature for mammalian ADP-ribosyltransferases
- (2010) Michael O. Hottiger et al. TRENDS IN BIOCHEMICAL SCIENCES
- Poly(ADP-ribose) polymerase-1 (PARP-1) and its therapeutic implications
- (2010) Rupinder K. Sodhi et al. VASCULAR PHARMACOLOGY
- Inhibition of matrix metalloproteinase-2 by PARP inhibitors
- (2009) Adrian C. Nicolescu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP
- (2009) Edward Thorp et al. Cell Metabolism
- Pharmacotherapy of coronary atherosclerosis
- (2009) Aloke V Finn et al. EXPERT OPINION ON PHARMACOTHERAPY
- Thieno[2,3-c]Isoquinolin-5-one, a Potent Poly(ADP-Ribose) Polymerase Inhibitor, Promotes Atherosclerotic Plaque Regression in High-Fat Diet-Fed Apolipoprotein E-Deficient Mice: Effects on Inflammatory Markers and Lipid Content
- (2009) C. P. Hans et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1
- (2009) S. B. Rajamohan et al. MOLECULAR AND CELLULAR BIOLOGY
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Nicotinamide Prevents NAD+ Depletion and Protects Neurons Against Excitotoxicity and Cerebral Ischemia: NAD+ Consumption by SIRT1 may Endanger Energetically Compromised Neurons
- (2009) Dong Liu et al. NEUROMOLECULAR MEDICINE
- Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites
- (2009) Matthias Altmeyer et al. NUCLEIC ACIDS RESEARCH
- Protective Effects of PARP-1 Knockout on Dyslipidemia-Induced Autonomic and Vascular Dysfunction in ApoE−/− Mice: Effects on eNOS and Oxidative Stress
- (2009) Chetan P. Hans et al. PLoS One
- Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome
- (2009) N. Dani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of the Peroxynitrite-Poly(ADP-Ribose) Polymerase Pathway in Human Disease
- (2008) Pal Pacher et al. AMERICAN JOURNAL OF PATHOLOGY
- Activation and Overexpression of PARP-1 in Circulating Mononuclear Cells Promote TNF-α and IL-6 Expression in Patients with Unstable Angina
- (2008) Dan Huang et al. ARCHIVES OF MEDICAL RESEARCH
- Poly (ADP-ribose) Polymerase Inhibition Improves Endothelial Dysfunction Induced by Hyperhomocysteinemia in Rats
- (2008) Xian Yu et al. CARDIOVASCULAR DRUGS AND THERAPY
- Differential effects of PARP inhibition on vascular cell survival and ACAT-1 expression favouring atherosclerotic plaque stability
- (2008) C. P. Hans et al. CARDIOVASCULAR RESEARCH
- Hyperelongated biglycan: the surreptitious initiator of atherosclerosis
- (2008) Peter J Little et al. CURRENT OPINION IN LIPIDOLOGY
- Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation
- (2008) Anton S. McCourtie et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Inhibition of the activity of poly (ADP-ribose) polymerase reduces heart ischaemia/reperfusion injuryviasuppressing JNK-mediated AIF translocation
- (2008) Zhao-Feng Song et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Poly(ADP-Ribose) Polymerase Mediates Inflammation in a Mouse Model of Contact Hypersensitivity
- (2008) Peter Bai et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation
- (2008) Nirmal K. Phulwani et al. JOURNAL OF NEUROCHEMISTRY
- A randomized, placebo-controlled trial to evaluate the tolerability, safety, pharmacokinetics, and pharmacodynamics of a potent inhibitor of poly(ADP-ribose) polymerase (INO-1001) in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: results of the TIMI 37 trial
- (2008) David A. Morrow et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- Regulation of Transcription Factor NFAT by ADP-Ribosylation
- (2008) O. A. Olabisi et al. MOLECULAR AND CELLULAR BIOLOGY
- Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells
- (2008) Rut Valdor et al. MOLECULAR IMMUNOLOGY
- Toward specific functions of poly(ADP-ribose) polymerase-2
- (2008) José Yélamos et al. TRENDS IN MOLECULAR MEDICINE
- Heart Disease and Stroke Statistics—2008 Update
- (2007) et al. CIRCULATION
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now