Cathepsin Protease Inhibition Reduces Endometriosis Lesion Establishment

Retinoic Acid Biosynthesis Is Impaired in Human and Murine Endometriosis1

(2014) Keely Pierzchalski et al.   BIOLOGY OF REPRODUCTION

TGF-β Signaling, Activated Stromal Fibroblasts, and Cysteine Cathepsins B and L Drive the Invasive Growth of Human Melanoma Cells

(2012) Miao Yin et al.   AMERICAN JOURNAL OF PATHOLOGY

Role for Cysteine Protease Cathepsins in Heart Disease

(2012) Xian Wu Cheng et al.   CIRCULATION

Retinoic acid suppresses growth of lesions, inhibits peritoneal cytokine secretion, and promotes macrophage differentiation in an immunocompetent mouse model of endometriosis

(2012) Friedrich Wieser et al.   FERTILITY AND STERILITY

Pharmacologic therapies in endometriosis: a systematic review

(2012) Sérgio Reis Soares et al.   FERTILITY AND STERILITY

Patient specific proteolytic activity of monocyte-derived macrophages and osteoclasts predicted with temporal kinase activation states during differentiation

(2012) Keon-Young Park et al.   Integrative Biology

Tumor necrosis factor alpha stimulates cathepsin K and V activity via juxtacrine monocyte–endothelial cell signaling and JNK activation

(2012) Philip M. Keegan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Manipulating substrate and pH in zymography protocols selectively distinguishes cathepsins K, L, S, and V activity in cells and tissues

(2011) Catera L. Wilder et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Inhibitors of cathepsin K: a patent review (2004 – 2010)

(2011) Jac Wijkmans et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Cathepsin S inhibitors: 2004 – 2010

(2011) Alice Lee-Dutra et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer

(2011) Binbin Chen et al.   Journal of Translational Medicine

Cathepsin K: its skeletal actions and role as a therapeutic target in osteoporosis

(2011) Aline G. Costa et al.   Nature Reviews Rheumatology

Detection of femtomole quantities of mature cathepsin K with zymography

(2010) Weiwei A. Li et al.   ANALYTICAL BIOCHEMISTRY

Endometriosis

(2010) Linda C. Giudice   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacological inhibitors to identify roles of cathepsin K in cell-based studies: a comparison of available tools

(2009) Sylvie Desmarais et al.   BIOLOGICAL CHEMISTRY

Cathepsin K inhibitors for osteoporosis and potential off-target effects

(2009) Dieter Brömme et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription

(2008) Anitha S. Nair et al.   FERTILITY AND STERILITY