Metformin and prostate cancer stem cells: a novel therapeutic target
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Title
Metformin and prostate cancer stem cells: a novel therapeutic target
Authors
Keywords
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Journal
PROSTATE CANCER AND PROSTATIC DISEASES
Volume 18, Issue 4, Pages 303-309
Publisher
Springer Nature
Online
2015-07-28
DOI
10.1038/pcan.2015.35
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Note: Only part of the references are listed.- Metformin: From Mechanisms of Action to Therapies
- (2014) Marc Foretz et al. Cell Metabolism
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- Metformin Use and Prostate Cancer Risk
- (2014) Mark A. Preston et al. EUROPEAN UROLOGY
- Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- (2014) Anila K. Madiraju et al. NATURE
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- (2014) H G Nguyen et al. ONCOGENE
- Metformin: A Potential Therapeutic Agent for Recurrent Colon Cancer
- (2014) Pratima Nangia-Makker et al. PLoS One
- Effect of Metformin on Cancer Risk and Treatment Outcome of Prostate Cancer: A Meta-Analysis of Epidemiological Observational Studies
- (2014) Hongliang Yu et al. PLoS One
- Differential expression of stem cell markers and ABCG2 in recurrent prostate cancer
- (2014) Esra Guzel et al. PROSTATE
- Antidiabetic Drug Metformin Prevents Progression of Pancreatic Cancer by Targeting in Part Cancer Stem Cells and mTOR Signaling
- (2014) Altaf Mohammed et al. Translational Oncology
- Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages
- (2014) Jia Wang et al. Nature Communications
- Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
- (2014) William W Wheaton et al. eLife
- Understanding and targeting cancer stem cells: therapeutic implications and challenges
- (2013) Ke Chen et al. ACTA PHARMACOLOGICA SINICA
- Therapeutic strategies targeting cancer stem cells
- (2013) Xiaoyan Ning et al. CANCER BIOLOGY & THERAPY
- The LKB1-AMPK Pathway—Friend or Foe in Cancer?
- (2013) D. Grahame Hardie CANCER CELL
- New insights into prostate cancer stem cells
- (2013) Xin Chen et al. CELL CYCLE
- SOX2 plays a critical role in EGFR-mediated self-renewal of human prostate cancer stem-like cells
- (2013) Adrian P. Rybak et al. CELLULAR SIGNALLING
- Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response
- (2013) V. E. Zannella et al. CLINICAL CANCER RESEARCH
- EAU Guidelines on Prostate Cancer. Part II: Treatment of Advanced, Relapsing, and Castration-Resistant Prostate Cancer
- (2013) Axel Heidenreich et al. EUROPEAN UROLOGY
- Potential applications for biguanides in oncology
- (2013) Michael Pollak JOURNAL OF CLINICAL INVESTIGATION
- Metformin Use and All-Cause and Prostate Cancer–Specific Mortality Among Men With Diabetes
- (2013) David Margel et al. JOURNAL OF CLINICAL ONCOLOGY
- Metformin Inhibits the Growth of Human Pancreatic Cancer Xenografts
- (2013) Krisztina Kisfalvi et al. PANCREAS
- Human Prostate Side Population Cells Demonstrate Stem Cell Properties in Recombination with Urogenital Sinus Mesenchyme
- (2013) Barbara A. Foster et al. PLoS One
- Identification and Characterization of Cells with Cancer Stem Cell Properties in Human Primary Lung Cancer Cell Lines
- (2013) Ping Wang et al. PLoS One
- Low Concentrations of Metformin Selectively Inhibit CD133+ Cell Proliferation in Pancreatic Cancer and Have Anticancer Action
- (2013) Shanmiao Gou et al. PLoS One
- Early Human Prostate Adenocarcinomas Harbor Androgen-Independent Cancer Cells
- (2013) Rita R. Fiñones et al. PLoS One
- Effects of Metformin on CD133+ Colorectal Cancer Cells in Diabetic Patients
- (2013) Yanfei Zhang et al. PLoS One
- Metformin Targets the Metabolic Achilles Heel of Human Pancreatic Cancer Stem Cells
- (2013) Enza Lonardo et al. PLoS One
- Enrichment of putative prostate cancer stem cells after androgen deprivation: Upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines
- (2013) Daniel Seiler et al. PROSTATE
- Increased expression of putative cancer stem cell markers in the bone marrow of prostate cancer patients is associated with bone metastasis progression
- (2013) Estelle Ricci et al. PROSTATE
- Searching for Prostate Cancer Stem Cells: Markers and Methods
- (2013) Benjamin Sharpe et al. Stem Cell Reviews and Reports
- Aldehyde dehydrogenase and ATP binding cassette transporter G2 (ABCG2) functional assays isolate different populations of prostate stem cells where ABCG2 function selects for cells with increased stem cell activity
- (2013) Kalyan J Gangavarapu et al. Stem Cell Research & Therapy
- Suppression of Acquired Docetaxel Resistance in Prostate Cancer through Depletion of Notch- and Hedgehog-Dependent Tumor-Initiating Cells
- (2012) Josep Domingo-Domenech et al. CANCER CELL
- Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
- (2012) Jeffrey A. Magee et al. CANCER CELL
- Metformin selectively affects human glioblastoma tumor-initiating cell viability
- (2012) Roberto Würth et al. CELL CYCLE
- Understanding cancer stem cell heterogeneity and plasticity
- (2012) Dean G Tang CELL RESEARCH
- The PSA−/lo Prostate Cancer Cell Population Harbors Self-Renewing Long-Term Tumor-Propagating Cells that Resist Castration
- (2012) Jichao Qin et al. Cell Stem Cell
- Cancer Stem Cells: Current Status and Evolving Complexities
- (2012) Jane E. Visvader et al. Cell Stem Cell
- HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells
- (2012) N. Duru et al. CLINICAL CANCER RESEARCH
- Tumorspheres derived from prostate cancer cells possess chemoresistant and cancer stem cell properties
- (2012) Linlin Zhang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Multipotent and unipotent progenitors contribute to prostate postnatal development
- (2012) Marielle Ousset et al. NATURE CELL BIOLOGY
- Adaptation or selection—mechanisms of castration-resistant prostate cancer
- (2012) Yang Zong et al. Nature Reviews Urology
- Identification of CD166 as a Surface Marker for Enriching Prostate Stem/Progenitor and Cancer Initiating Cells
- (2012) Jing Jiao et al. PLoS One
- Metformin enhances the antiproliferative and apoptotic effect of bicalutamide in prostate cancer
- (2012) A J Colquhoun et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Investigating Metformin for Cancer Prevention and Treatment: The End of the Beginning
- (2012) Michael N. Pollak Cancer Discovery
- Metformin Inhibits Cell Proliferation, Migration and Invasion by Attenuating CSC Function Mediated by Deregulating miRNAs in Pancreatic Cancer Cells
- (2011) B. Bao et al. Cancer Prevention Research
- Abstract 5162: MicroRNA regulation of epidermal lineage differentiation of NT2/D1 embryonal carcinoma cells
- (2011) Ritu Kushwaha et al. CANCER RESEARCH
- Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1
- (2011) I. Ben Sahra et al. CANCER RESEARCH
- Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
- (2011) D. Iliopoulos et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
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- Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro
- (2011) Irina N. Alimova et al. CELL CYCLE
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- (2011) Hangwen Li et al. JOURNAL OF SURGICAL ONCOLOGY
- Metformin and cancer: new applications for an old drug
- (2011) Taxiarchis V. Kourelis et al. MEDICAL ONCOLOGY
- Cells of origin in cancer
- (2011) Jane E. Visvader NATURE
- NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation
- (2011) C R Jeter et al. ONCOGENE
- Increased expression of putative cancer stem cell markers in primary prostate cancer is associated with progression of bone metastases
- (2011) Marc Colombel et al. PROSTATE
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- (2010) Mahvash Zakikhani et al. BREAST CANCER RESEARCH AND TREATMENT
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- (2010) M. M. Shen et al. GENES & DEVELOPMENT
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- (2009) H. A. Hirsch et al. CANCER RESEARCH
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- (2009) R. Rattan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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- Prostate Cancer Stem Cells: A New Target for Therapy
- (2008) Norman J. Maitland et al. JOURNAL OF CLINICAL ONCOLOGY
- Generation of a prostate from a single adult stem cell
- (2008) Kevin G. Leong et al. NATURE
- The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
- (2008) I Ben Sahra et al. ONCOGENE
- Cancer stem cell markers in common cancers – therapeutic implications
- (2008) Thomas Klonisch et al. TRENDS IN MOLECULAR MEDICINE
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