Adaptation or selection—mechanisms of castration-resistant prostate cancer
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Title
Adaptation or selection—mechanisms of castration-resistant prostate cancer
Authors
Keywords
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Journal
Nature Reviews Urology
Volume 10, Issue 2, Pages 90-98
Publisher
Springer Nature
Online
2012-12-18
DOI
10.1038/nrurol.2012.237
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Related references
Note: Only part of the references are listed.- Cancer statistics, 2012
- (2012) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cancer Stem Cells: Impact, Heterogeneity, and Uncertainty
- (2012) Jeffrey A. Magee et al. CANCER CELL
- Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation
- (2012) Nahyun Choi et al. CANCER CELL
- Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
- (2012) R. Hu et al. CANCER RESEARCH
- Converting Cancer Therapies into Cures: Lessons from Infectious Diseases
- (2012) Michael S. Glickman et al. CELL
- Management of Metastatic Castration-Resistant Prostate Cancer
- (2012) Deborah Mukherji et al. DRUGS
- Pathogenesis of prostatic small cell carcinoma involves the inactivation of the P53 pathway
- (2012) Hongbing Chen et al. ENDOCRINE-RELATED CANCER
- Androgen receptor (AR) aberrations in castration-resistant prostate cancer
- (2012) Kati K. Waltering et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- The mutational landscape of lethal castration-resistant prostate cancer
- (2012) Catherine S. Grasso et al. NATURE
- Stem-Like Cells with Luminal Progenitor Phenotype Survive Castration in Human Prostate Cancer
- (2012) Markus Germann et al. STEM CELLS
- Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
- (2011) Changmeng Cai et al. CANCER CELL
- Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung
- (2011) Kate D. Sutherland et al. CANCER CELL
- Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth
- (2011) David J. Mulholland et al. CANCER CELL
- Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
- (2011) Brett S. Carver et al. CANCER CELL
- Activation of the Androgen Receptor by Intratumoral Bioconversion of Androstanediol to Dihydrotestosterone in Prostate Cancer
- (2011) James L. Mohler et al. CANCER RESEARCH
- Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
- (2011) T. W. Friedlander et al. CANCER RESEARCH
- Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
- (2011) Y. Sun et al. CANCER RESEARCH
- Insulin Increases De Novo Steroidogenesis in Prostate Cancer Cells
- (2011) A. A. Lubik et al. CANCER RESEARCH
- Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors
- (2011) C. Cai et al. CANCER RESEARCH
- Androgen Receptor Rediscovered: The New Biology and Targeting the Androgen Receptor Therapeutically
- (2011) Charles J. Ryan et al. JOURNAL OF CLINICAL ONCOLOGY
- The cancer stem cell: premises, promises and challenges
- (2011) Hans Clevers NATURE MEDICINE
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- Advancing a clinically relevant perspective of the clonal nature of cancer
- (2011) C. Ruiz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
- (2011) K.-H. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal
- (2011) S. Memarzadeh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Compensatory Upregulation of Tyrosine Kinase Etk/BMX in Response to Androgen Deprivation Promotes Castration-Resistant Growth of Prostate Cancer Cells
- (2010) B. Dai et al. CANCER RESEARCH
- High Aldehyde Dehydrogenase Activity Identifies Tumor-Initiating and Metastasis-Initiating Cells in Human Prostate Cancer
- (2010) Christel van den Hoogen et al. CANCER RESEARCH
- Nuclear androgen receptor staining in bone metastases is related to a poor outcome in prostate cancer patients
- (2010) S Crnalic et al. ENDOCRINE-RELATED CANCER
- N-cadherin increases after androgen deprivation and is associated with metastasis in prostate cancer
- (2010) Karin Jennbacken et al. ENDOCRINE-RELATED CANCER
- The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
- (2010) Ankur Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- Duration of First Off-Treatment Interval Is Prognostic for Time to Castration Resistance and Death in Men With Biochemical Relapse of Prostate Cancer Treated on a Prospective Trial of Intermittent Androgen Deprivation
- (2010) Evan Y. Yu et al. JOURNAL OF CLINICAL ONCOLOGY
- Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study
- (2010) Howard I Scher et al. LANCET
- Primitive origins of prostate cancer: In vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells
- (2010) Andrew S. Goldstein et al. Molecular Oncology
- B-cell-derived lymphotoxin promotes castration-resistant prostate cancer
- (2010) Massimo Ammirante et al. NATURE
- Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
- (2010) Hiroshi Tanaka et al. NATURE MEDICINE
- Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
- (2010) P. A. Watson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Basal epithelial stem cells are efficient targets for prostate cancer initiation
- (2010) D. A. Lawson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Androgen receptors are differentially expressed in Gleason patterns of prostate cancer and down-regulated in matched lymph node metastases
- (2010) Achim Fleischmann et al. PROSTATE
- Identification of a Cell of Origin for Human Prostate Cancer
- (2010) A. S. Goldstein et al. SCIENCE
- Androgen receptor expression is associated with prostate cancer-specific survival in castrate patients with metastatic disease
- (2009) Michael J. Donovan et al. BJU INTERNATIONAL
- Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-Induced Ubiquitination
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- A luminal epithelial stem cell that is a cell of origin for prostate cancer
- (2009) Xi Wang et al. NATURE
- Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
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- In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue
- (2009) Natalia Guzmán-Ramírez et al. PROSTATE
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
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- (2008) S. M. Dehm et al. CANCER RESEARCH
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- (2008) R. Snoek et al. CLINICAL CANCER RESEARCH
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- (2008) Gerhardt Attard et al. JOURNAL OF CLINICAL ONCOLOGY
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