Iterative polyketide biosynthesis by modular polyketide synthases in bacteria
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Iterative polyketide biosynthesis by modular polyketide synthases in bacteria
Authors
Keywords
Biosynthesis, Natural products, Polyketides, Type I PKS, Iterative PKS
Journal
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
Volume 100, Issue 2, Pages 541-557
Publisher
Springer Nature
Online
2015-11-09
DOI
10.1007/s00253-015-7093-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Freedom and Constraint in Engineered Noncolinear Polyketide Assembly Lines
- (2015) Yuki Sugimoto et al. CHEMISTRY & BIOLOGY
- Bioactive Polycyclic Tetramate Macrolactams from Lysobacter enzymogenes and Their Absolute Configurations by Theoretical ECD Calculations
- (2015) Liangxiong Xu et al. JOURNAL OF NATURAL PRODUCTS
- Decoding and reprogramming complex polyketide assembly lines: prospects for synthetic biology
- (2015) Christian Hertweck TRENDS IN BIOCHEMICAL SCIENCES
- Bioinformatical Analysis of the Sequences, Structures and Functions of Fungal Polyketide Synthase Product Template Domains
- (2015) Lu Liu et al. Scientific Reports
- Heterologous Reconstitution of Ikarugamycin Biosynthesis inE. coli
- (2014) Janine Antosch et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mechanistic Insights into Polycycle Formation by Reductive Cyclization in Ikarugamycin Biosynthesis
- (2014) Guangtao Zhang et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Rational Design of Modular Polyketide Synthases: Morphing the Aureothin Pathway into a Luteoreticulin Assembly Line
- (2014) Yuki Sugimoto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Iterative Assembly of Two Separate Polyketide Chains by the Same Single-Module Bacterial Polyketide Synthase in the Biosynthesis of HSAF
- (2014) Yaoyao Li et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biosynthesis of Crocacin Involves an Unusual Hydrolytic Release Domain Showing Similarity to Condensation Domains
- (2014) Stefan Müller et al. CHEMISTRY & BIOLOGY
- A Close Look at a Ketosynthase from a Trans-Acyltransferase Modular Polyketide Synthase
- (2014) Darren C. Gay et al. STRUCTURE
- Polyunsaturated fatty acid biosynthesis in myxobacteria: different PUFA synthases and their product diversity
- (2014) Katja Gemperlein et al. Chemical Science
- Biosynthesis of Antimycins with a Reconstituted 3-Formamidosalicylate Pharmacophore in Escherichia coli
- (2014) Joyce Liu et al. ACS Synthetic Biology
- Multifactorial Control of Iteration Events in a Modular Polyketide Assembly Line
- (2013) Benjamin Busch et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- ATrans-Acting Ketoreductase in Biosynthesis of a Symmetric Polyketide Dimer SIA7248
- (2013) Yi Zou et al. CHEMBIOCHEM
- Engineering polyketide synthases and nonribosomal peptide synthetases
- (2013) Gavin J Williams CURRENT OPINION IN STRUCTURAL BIOLOGY
- Biochemical Determination of Enzyme-Bound Metabolites: Preferential Accumulation of a Programmed Octaketide on the Enediyne Polyketide Synthase CalE8
- (2013) Katherine Belecki et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Vinylogous chain branching catalysed by a dedicated polyketide synthase module
- (2013) Tom Bretschneider et al. NATURE
- Aromatic Polyketides Produced by Bacterial Iterative Type I Polyketide Synthases
- (2013) Qi Zhang et al. ACS Catalysis
- Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS
- (2013) Katja Maria Fisch RSC Advances
- Environmental Control of the Calicheamicin Polyketide Synthase Leads to Detection of a Programmed Octaketide and a Proposal for Enediyne Biosynthesis
- (2012) Katherine Belecki et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Structural analysis of protein–protein interactions in type I polyketide synthases
- (2012) Wei Xu et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Synthetic biological approaches to natural product biosynthesis
- (2012) Jaclyn M Winter et al. CURRENT OPINION IN BIOTECHNOLOGY
- Expanding nature's chemical repertoire through metabolic engineering and biocatalysis
- (2012) Ben Shen et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Identification of phoslactomycin biosynthetic gene clusters from Streptomyces platensis SAM-0654 and characterization of PnR1 and PnR2 as positive transcriptional regulators
- (2012) Yun-Liang Chen et al. GENE
- Interchenar Retrotransfer of Aureothin Intermediates in an Iterative Polyketide Synthase Module
- (2012) Benjamin Busch et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis of (R)-Mellein by a Partially Reducing Iterative Polyketide Synthase
- (2012) Huihua Sun et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Reprogramming a module of the 6-deoxyerythronolide B synthase for iterative chain elongation
- (2012) S. Kapur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Discrete acyltransferases involved in polyketide biosynthesis
- (2012) Ewa Maria Musiol et al. MedChemComm
- Unusual Activities of the Thioesterase Domain for the Biosynthesis of the Polycyclic Tetramate Macrolactam HSAF in Lysobacter enzymogenes C3
- (2011) Lili Lou et al. BIOCHEMISTRY
- Supramolecular Templating in Kirromycin Biosynthesis: The Acyltransferase KirCII Loads Ethylmalonyl-CoA Extender onto a Specific ACP of the trans-AT PKS
- (2011) Ewa M. Musiol et al. CHEMISTRY & BIOLOGY
- Protein engineering towards natural product synthesis and diversification
- (2011) Angelica O. Zabala et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation
- (2011) Shunji Takahashi et al. Nature Chemical Biology
- Genomics-inspired discovery of natural products
- (2010) Jaclyn M Winter et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Functional analysis of fungal polyketide biosynthesis genes
- (2010) Isao Fujii JOURNAL OF ANTIBIOTICS
- Biosynthesis of HSAF, a Tetramic Acid-Containing Macrolactam from Lysobacter enzymogenes
- (2010) Lili Lou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Characterization of Tiacumicin B Biosynthetic Gene Cluster Affording Diversified Tiacumicin Analogues and Revealing a Tailoring Dihalogenase
- (2010) Yi Xiao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B
- (2010) Wei Ding et al. Molecular BioSystems
- Biosynthesis of polyketides by trans-AT polyketide synthases
- (2010) Jörn Piel NATURAL PRODUCT REPORTS
- New insights into the formation of fungal aromatic polyketides
- (2010) Jason M. Crawford et al. NATURE REVIEWS MICROBIOLOGY
- Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria
- (2010) J. A. V. Blodgett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Biosynthetic Logic of Polyketide Diversity
- (2009) Christian Hertweck ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Organisation of the Biosynthetic Gene Cluster and Tailoring Enzymes in the Biosynthesis of the Tetracyclic Quinone Glycoside Antibiotic Polyketomycin
- (2009) Martina Daum et al. CHEMBIOCHEM
- Dissection of Two Acyl-Transfer Reactions Centered on Acyl-S-Carrier Protein Intermediates for Incorporating 5-Chloro-6-methyl-O-methylsalicyclic Acid into Chlorothricin
- (2009) Qing-Li He et al. CHEMBIOCHEM
- Deciphering Pactamycin Biosynthesis and Engineered Production of New Pactamycin Analogues
- (2009) Takuya Ito et al. CHEMBIOCHEM
- Revisiting the modularity of modular polyketide synthases
- (2009) Chaitan Khosla et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Production of Octaketide Polyenes by the Calicheamicin Polyketide Synthase CalE8: Implications for the Biosynthesis of Enediyne Core Structures
- (2009) Katherine Belecki et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Evolution of metabolic diversity in polyketide-derived pyrones: Using the non-colinear aureothin assembly line as a model system
- (2009) Benjamin Busch et al. PHYTOCHEMISTRY
- Exploring the Biosynthesis of Natural Products and Their Inherent Suitability for the Rational Design of Desirable Compounds through Genetic Engineering
- (2008) Kenji WATANABE BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Characterization of the Azinomycin B Biosynthetic Gene Cluster Revealing a Different Iterative Type I Polyketide Synthase for Naphthoate Biosynthesis
- (2008) Qunfei Zhao et al. CHEMISTRY & BIOLOGY
- Genome Mining for Novel Natural Product Discovery
- (2008) Gregory L. Challis JOURNAL OF MEDICINAL CHEMISTRY
- Stereochemical Determination and Complex Biosynthetic Assembly of Etnangien, a Highly Potent RNA Polymerase Inhibitor from the Myxobacterium Sorangium cellulosum
- (2008) Dirk Menche et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Role of Tandem Acyl Carrier Protein Domains in Polyunsaturated Fatty Acid Biosynthesis
- (2008) Hui Jiang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- cis-Δ2,3-Double Bond of Phoslactomycins Is Generated by a Post-PKS Tailoring Enzyme
- (2008) Nadaraj Palaniappan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Bacterial β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH): An Attractive Target for the Design of New Broad-Spectrum Antimicrobial Agents
- (2008) Miguel Perez et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Biosynthesis of polyketide synthase extender units
- (2008) Yolande A. Chan et al. NATURAL PRODUCT REPORTS
- Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism
- (2008) S. G. Van Lanen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel Intermolecular Iterative Mechanism for Biosynthesis of Mycoketide Catalyzed by a Bimodular Polyketide Synthase
- (2008) Tarun Chopra et al. PLOS BIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started