Mechanistic Insights into Polycycle Formation by Reductive Cyclization in Ikarugamycin Biosynthesis

Heterologous Reconstitution of Ikarugamycin Biosynthesis inE. coli

(2014) Janine Antosch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Streptomyces harbinensis sp. nov., an endophytic, ikarugamycin-producing actinomycete isolated from soybean root [Glycine max (L.) Merr.]

(2013) C. Liu et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Bioactive natural products from Lysobacter

(2012) Yunxuan Xie et al.   NATURAL PRODUCT REPORTS

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

(2012) Fernando Geu-Flores et al.   NATURE

3-Hydroxylation of the polycyclic tetramate macrolactam in the biosynthesis of antifungal HSAF from Lysobacter enzymogenes C3

(2012) Yaoyao Li et al.   MedChemComm

Unusual Activities of the Thioesterase Domain for the Biosynthesis of the Polycyclic Tetramate Macrolactam HSAF in Lysobacter enzymogenes C3

(2011) Lili Lou et al.   BIOCHEMISTRY

Engineered Thermoplasma acidophilum factor F3 mimics human aminopeptidase N (APN) as a target for anticancer drug development

(2011) Jing Su et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Ikarugamycin induces DNA damage, intracellular calcium increase, p38 MAP kinase activation and apoptosis in HL-60 human promyelocytic leukemia cells

(2011) Ruxandra Popescu et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A

(2011) Hak Joong Kim et al.   NATURE

Construction and co-expression of a polycistronic plasmid encoding carbonyl reductase and glucose dehydrogenase for production of ethyl (S)-4-chloro-3-hydroxybutanoate

(2010) Qi Ye et al.   BIORESOURCE TECHNOLOGY

Biosynthesis of HSAF, a Tetramic Acid-Containing Macrolactam from Lysobacter enzymogenes

(2010) Lili Lou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Discovery of Polycyclic Tetramate Macrolactams from an EnvironmentalStreptomycesStrain

(2010) Shugeng Cao et al.   ORGANIC LETTERS

Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria

(2010) J. A. V. Blodgett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tartrolon D, a Cytotoxic Macrodiolide from the Marine-Derived ActinomyceteStreptomycessp. MDG-04-17-069

(2009) Marta Pérez et al.   JOURNAL OF NATURAL PRODUCTS

Authentic Heterologous Expression of the Tenellin Iterative Polyketide Synthase Nonribosomal Peptide Synthetase Requires Coexpression with an Enoyl Reductase

(2008) Laura M. Halo et al.   CHEMBIOCHEM