PD-1–Mediated Attrition of Polyfunctional Memory CD8+ T Cells in Chronic Toxoplasma Infection

The CD8 T-cell road to immunotherapy of toxoplasmosis

(2011) Rajarshi Bhadra et al.   Immunotherapy

Cutting Edge: CD40-CD40 Ligand Pathway Plays a Critical CD8-Intrinsic and -Extrinsic Role during Rescue of Exhausted CD8 T Cells

(2011) R. Bhadra et al.   JOURNAL OF IMMUNOLOGY

Early Induction of Polyfunctional Simian Immunodeficiency Virus (SIV)-Specific T Lymphocytes and Rapid Disappearance of SIV from Lymph Nodes of Sooty Mangabeys during Primary Infection

(2011) M. Meythaler et al.   JOURNAL OF IMMUNOLOGY

Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade

(2011) R. Bhadra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Removal of Toxoplasma gondii Cysts from the Brain by Perforin-Mediated Activity of CD8+ T Cells

(2010) Yasuhiro Suzuki et al.   AMERICAN JOURNAL OF PATHOLOGY

Visualizing the Functional Diversification of CD8+ T Cell Responses in Lymph Nodes

(2010) Hélène Beuneu et al.   IMMUNITY

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice

(2010) Scott N. Mueller et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4 T-Cell Help Programs a Change in CD8 T-Cell Function Enabling Effective Long-Term Control of Murine Gammaherpesvirus 68: Role of PD-1-PD-L1 Interactions

(2010) P. Dias et al.   JOURNAL OF VIROLOGY

Expanded Polyfunctional T Cell Response to Mycobacterial Antigens in TB Disease and Contraction Post-Treatment

(2010) James M. Young et al.   PLoS One

Absence of Both IL-7 and IL-15 Severely Impairs the Development of CD8+ T Cell Response against Toxoplasma gondii

(2010) Rajarshi Bhadra et al.   PLoS One

Current status of toxoplasmosis vaccine development

(2009) Józef Kur et al.   Expert Review of Vaccines

Targeted Cleavage of Signaling Proteins by Caspase 3 Inhibits T Cell Receptor Signaling in Anergic T Cells

(2008) Irene Puga et al.   IMMUNITY

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY