Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

IFN-Inducible GTPases in Host Cell Defense

(2012) Bae-Hoon Kim et al.   Cell Host & Microbe

Foodborne Toxoplasmosis

(2012) J. L. Jones et al.   CLINICAL INFECTIOUS DISEASES

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

(2012) Masahiro Yamamoto et al.   IMMUNITY

The GTPase Activity of Murine Guanylate-binding Protein 2 (mGBP2) Controls the Intracellular Localization and Recruitment to the Parasitophorous Vacuole ofToxoplasma gondii

(2012) Elisabeth Kravets et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication

(2012) D. Degrandi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GBP5 Promotes NLRP3 Inflammasome Assembly and Immunity in Mammals

(2012) A. R. Shenoy et al.   SCIENCE

A Toxoplasma gondii Pseudokinase Inhibits Host IRG Resistance Proteins

(2012) Martin C. Fleckenstein et al.   PLOS BIOLOGY

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

(2012) Wendy Niedelman et al.   PLoS Pathogens

The Polymorphic Pseudokinase ROP5 Controls Virulence in Toxoplasma gondii by Regulating the Active Kinase ROP18

(2012) Michael S. Behnke et al.   PLoS Pathogens

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

(2011) Jonathan C Howard et al.   CURRENT OPINION IN MICROBIOLOGY

A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication

(2011) Alexandra Nordmann et al.   FASEB JOURNAL

Immunity-related GTPase M (IRGM) Proteins Influence the Localization of Guanylate-binding Protein 2 (GBP2) by Modulating Macroautophagy

(2011) Maria K. Traver et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens

(2011) Oliver Liesenfeld et al.   PLoS One

Determinants of GBP Recruitment to Toxoplasma gondii Vacuoles and the Parasitic Factors That Control It

(2011) Sebastian Virreira Winter et al.   PLoS One

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

(2011) M. L. Reese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

(2011) M. S. Behnke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection

(2011) B.-H. Kim et al.   SCIENCE

Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii-Secreted Kinase Promotes Macrophage Survival and Virulence

(2010) Sarah J. Fentress et al.   Cell Host & Microbe

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

(2010) Aliaksandr Khaminets et al.   CELLULAR MICROBIOLOGY

Phosphorylation of Mouse Immunity-Related GTPase (IRG) Resistance Proteins Is an Evasion Strategy for Virulent Toxoplasma gondii

(2010) Tobias Steinfeldt et al.   PLOS BIOLOGY

Forward Genetics inToxoplasma gondiiReveals a Family of Rhoptry Kinases That Mediates Pathogenesis

(2009) L. David Sibley et al.   EUKARYOTIC CELL

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

Antiviral effects of the interferon-induced protein guanylate binding protein 1 and its interaction with the hepatitis C virus NS5B protein

(2009) Yasuhiro Itsui et al.   HEPATOLOGY

Balance of Irgm protein activities determines IFN-γ-induced host defense

(2009) Stanley C. Henry et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Evolutionarily Dynamic IFN-Inducible GTPase Proteins Play Conserved Immune Functions in Vertebrates and Cephalochordates

(2009) G. Li et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human Guanylate Binding Proteins Potentiate the Anti-Chlamydia Effects of Interferon-γ

(2009) Illya Tietzel et al.   PLoS One

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

(2009) Yang O. Zhao et al.   PLoS Pathogens

Population Structure ofToxoplasma gondii: Clonal Expansion Driven by Infrequent Recombination and Selective Sweeps

(2008) L. David Sibley et al.   Annual Review of Microbiology

Analyses of murine GBP homology clusters based on in silico, in vitro and in vivo studies

(2008) Alexandra Kresse et al.   BMC GENOMICS

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

(2008) Julia P Hunn et al.   EMBO JOURNAL

The Toxoplasma gondii Dense Granule Protein GRA7 Is Phosphorylated upon Invasion and Forms an Unexpected Association with the Rhoptry Proteins ROP2 and ROP4

(2008) J. D. Dunn et al.   INFECTION AND IMMUNITY