The role of mononuclear phagocytes in Ebola virus infection

Human dendritic cell subsets: an update

(2018) Matthew Collin et al.   IMMUNOLOGY

The origins and homeostasis of monocytes and tissue-resident macrophages in physiological situation

(2018) Yang Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Macrophage plasticity, polarization, and function in health and disease

(2018) Abbas Shapouri-Moghaddam et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Interferon-β and Interferon-γ Are Weak Inhibitors of Ebola Virus in Cell-Based Assays

(2017) Julie Dyall et al.   JOURNAL OF INFECTIOUS DISEASES

Phenotypic and functional consequences of different isolation protocols on skin mononuclear phagocytes

(2017) Rachel A. Botting et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages

(2017) Judith Olejnik et al.   JOURNAL OF VIROLOGY

The role of monocytes in models of infection by protozoan parasites

(2017) Shanshan Hu et al.   MOLECULAR IMMUNOLOGY

Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease

(2017) John C. Kash et al.   Science Translational Medicine

The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge

(2017) Patrick Younan et al.   mBio

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm

(2017) Patrick Younan et al.   mBio

A Systems Approach Reveals MAVS Signaling in Myeloid Cells as Critical for Resistance to Ebola Virus in Murine Models of Infection

(2017) Mukta Dutta et al.   Cell Reports

Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection

(2017) Mathieu Iampietro et al.   PLoS Pathogens

Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4

(2017) Chih-Yun Lai et al.   Frontiers in Microbiology

Transcriptome Analysis of Circulating Immune Cell Subsets Highlight the Role of Monocytes in Zaire Ebola Virus Makona Pathogenesis

(2017) Andrea R. Menicucci et al.   Frontiers in Immunology

Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

(2017) Anja Lüdtke et al.   Scientific Reports

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

(2017) Krista Versteeg et al.   Scientific Reports

In vivo Ebola virus infection leads to a strong innate response in circulating immune cells

(2016) Ignacio S. Caballero et al.   BMC GENOMICS

Ebola Virus Disease Is Characterized by Poor Activation and Reduced Levels of Circulating CD16 + Monocytes

(2016) Anja Lüdtke et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of Human and Murine T-Cell Immunoglobulin Mucin Domain 4 (TIM-4) IgV Domain Residues Critical for Ebola Virus Entry

(2016) Bethany A. Rhein et al.   JOURNAL OF VIROLOGY

Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection

(2016) Benjamin C. Yen et al.   JOURNAL OF VIROLOGY

A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues

(2016) Yen-Rei A. Yu et al.   PLoS One

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

(2016) Megan R. Edwards et al.   Cell Reports

The Myeloid LSECtin Is a DAP12-Coupled Receptor That Is Crucial for Inflammatory Response Induced by Ebola Virus Glycoprotein

(2016) Dianyuan Zhao et al.   PLoS Pathogens

Molecular mechanisms of Ebola virus pathogenesis: focus on cell death

(2015) L Falasca et al.   CELL DEATH AND DIFFERENTIATION

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells

(2015) Julie Helft et al.   IMMUNITY

Analysis of Ebola Virus Entry Into Macrophages

(2015) Franziska Dahlmann et al.   JOURNAL OF INFECTIOUS DISEASES

Suppressor of Cytokine Signaling 3 Is an Inducible Host Factor That Regulates Virus Egress during Ebola Virus Infection

(2015) Atsushi Okumura et al.   JOURNAL OF VIROLOGY

Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells

(2015) Philipp A. Ilinykh et al.   JOURNAL OF VIROLOGY

Particle-to-PFU Ratio of Ebola Virus Influences Disease Course and Survival in Cynomolgus Macaques

(2015) Kendra J. Alfson et al.   JOURNAL OF VIROLOGY

Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus

(2015) Ilhem Messaoudi et al.   NATURE REVIEWS MICROBIOLOGY

Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment

(2015) Yasuteru Sakurai et al.   SCIENCE

Innate immune evasion by filoviruses

(2015) Christopher F. Basler   VIROLOGY

Ebola Virus Entry: A Curious and Complex Series of Events

(2015) Sven Moller-Tank et al.   PLoS Pathogens

Interferon-γ Inhibits Ebola Virus Infection

(2015) Bethany A. Rhein et al.   PLoS Pathogens

Human and Mouse Mononuclear Phagocyte Networks: A Tale of Two Species?

(2015) Gary Reynolds et al.   Frontiers in Immunology

Successful treatment of advanced Ebola virus infection with T-705 (favipiravir) in a small animal model

(2014) Lisa Oestereich et al.   ANTIVIRAL RESEARCH

Measles Virus Suppresses RIG-I-like Receptor Activation in Dendritic Cells via DC-SIGN-Mediated Inhibition of PP1 Phosphatases

(2014) Annelies W. Mesman et al.   Cell Host & Microbe

Human Dermal CD14 + Cells Are a Transient Population of Monocyte-Derived Macrophages

(2014) Naomi McGovern et al.   IMMUNITY

Understanding organ dysfunction in Ebola virus disease

(2014) Tom E. Fletcher et al.   INTENSIVE CARE MEDICINE

The C-Type Lectin Macrophage Galactose-Type Lectin Impedes Migration of Immature APCs

(2014) S. J. van Vliet et al.   JOURNAL OF IMMUNOLOGY

Macrophage Polarization in Bacterial Infections

(2014) M. Benoit et al.   JOURNAL OF IMMUNOLOGY

Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses

(2014) Roosecelis Brasil Martines et al.   JOURNAL OF PATHOLOGY

Molecular Basis for Ebolavirus VP35 Suppression of Human Dendritic Cell Maturation

(2014) B. Yen et al.   JOURNAL OF VIROLOGY

Tim4- and MerTK-Mediated Engulfment of Apoptotic Cells by Mouse Resident Peritoneal Macrophages

(2014) C. Nishi et al.   MOLECULAR AND CELLULAR BIOLOGY

The Role of Macrophage Polarization in Infectious and Inflammatory Diseases

(2014) Adam C. Labonte et al.   MOLECULES AND CELLS

Emergence of Zaire Ebola Virus Disease in Guinea

(2014) Sylvain Baize et al.   NEW ENGLAND JOURNAL OF MEDICINE

Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

(2014) Beatriz Escudero-Pérez et al.   PLoS Pathogens

Mutual Antagonism between the Ebola Virus VP35 Protein and the RIG-I Activator PACT Determines Infection Outcome

(2013) Priya Luthra et al.   Cell Host & Microbe

Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

(2013) Suchita Bhattacharyya et al.   Cell Host & Microbe

Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor-dependent manner

(2013) Nicola F. Fletcher et al.   HEPATOLOGY

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

(2013) O. Martinez et al.   JOURNAL OF VIROLOGY

Comparative Virus Replication and Host Innate Responses in Human Cells Infected with Three Prevalent Clades (2.3.4, 2.3.2, and 7) of Highly Pathogenic Avian Influenza H5N1 Viruses

(2013) H. Sun et al.   JOURNAL OF VIROLOGY

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

(2013) N. M. Lubaki et al.   JOURNAL OF VIROLOGY

Role of the Phosphatidylserine Receptor TIM-1 in Enveloped-Virus Entry

(2013) S. Moller-Tank et al.   JOURNAL OF VIROLOGY

M2-polarized tumor-associated macrophages promoted epithelial–mesenchymal transition in pancreatic cancer cells, partially through TLR4/IL-10 signaling pathway

(2013) Chao-Ying Liu et al.   LABORATORY INVESTIGATION

TIM-family Proteins Promote Infection of Multiple Enveloped Viruses through Virion-associated Phosphatidylserine

(2013) Stephanie Jemielity et al.   PLoS Pathogens

The role of antigen-presenting cells in filoviral hemorrhagic fever: Gaps in current knowledge

(2012) Osvaldo Martinez et al.   ANTIVIRAL RESEARCH

Distribution of macrophage polarization markers in human atherosclerosis

(2012) J. Lauran Stöger et al.   ATHEROSCLEROSIS

Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells

(2012) A. N. Harman et al.   JOURNAL OF IMMUNOLOGY

Induction of Alternatively Activated Macrophages Enhances Pathogenesis during Severe Acute Respiratory Syndrome Coronavirus Infection

(2012) C. Page et al.   JOURNAL OF VIROLOGY

Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1

(2012) J. E. Kanter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques

(2012) N. A. Twenhafel et al.   VETERINARY PATHOLOGY

Mouse LSECtin as a model for a human Ebola virus receptor

(2011) Z. Pipirou et al.   GLYCOBIOLOGY

Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza

(2011) Wilbur H. Chen et al.   IMMUNOLOGY LETTERS

Cathepsin Cleavage Potentiates the Ebola Virus Glycoprotein To Undergo a Subsequent Fusion-Relevant Conformational Change

(2011) M. Brecher et al.   JOURNAL OF VIROLOGY

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

Ebola virus entry requires the cholesterol transporter Niemann–Pick C1

(2011) Jan E. Carette et al.   NATURE

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

(2011) A. S. Kondratowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein

(2011) Melinda A. Brindley et al.   VIROLOGY

Ebola Virion Attachment and Entry into Human Macrophages Profoundly Effects Early Cellular Gene Expression

(2011) Victoria Wahl-Jensen et al.   PLoS Neglected Tropical Diseases

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

(2011) Mohammad F. Saeed et al.   PLoS Pathogens

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

(2010) Takashi Satoh et al.   NATURE IMMUNOLOGY

Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis

(2010) Nadia Wauquier et al.   PLoS Neglected Tropical Diseases

Marburg Virus Evades Interferon Responses by a Mechanism Distinct from Ebola Virus

(2010) Charalampos Valmas et al.   PLoS Pathogens

Ebolavirusglycoprotein structure and mechanism of entry

(2009) Jeffrey E Lee et al.   Future Virology

The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide

(2009) H. Jin et al.   JOURNAL OF GENERAL VIROLOGY

Macrophage polarization and HIV-1 infection

(2009) Edana Cassol et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Ebolavirus VP24 Binding to Karyopherins Is Required for Inhibition of Interferon Signaling

(2009) M. Mateo et al.   JOURNAL OF VIROLOGY

Interaction between Ebola Virus Glycoprotein and Host Toll-Like Receptor 4 Leads to Induction of Proinflammatory Cytokines and SOCS1

(2009) A. Okumura et al.   JOURNAL OF VIROLOGY

Interactions of LSECtin and DC-SIGN/DC-SIGNR with viral ligands: Differential pH dependence, internalization and virion binding

(2008) Thomas Gramberg et al.   VIROLOGY