Molecular Basis for Ebolavirus VP35 Suppression of Human Dendritic Cell Maturation

Mutual Antagonism between the Ebola Virus VP35 Protein and the RIG-I Activator PACT Determines Infection Outcome

(2013) Priya Luthra et al.   Cell Host & Microbe

Ebola Virus Exploits a Monocyte Differentiation Program To Promote Its Entry

(2013) O. Martinez et al.   JOURNAL OF VIROLOGY

The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

(2013) N. M. Lubaki et al.   JOURNAL OF VIROLOGY

Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

(2012) Shridhar Bale et al.   PLoS Pathogens

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells

(2011) Lawrence W Leung et al.   IMMUNOLOGY AND CELL BIOLOGY

A simple, versatile and efficient method to genetically modify human monocyte-derived dendritic cells with HIV-1–derived lentiviral vectors

(2011) Grégory Berger et al.   Nature Protocols

Provision of Continuous Maturation Signaling to Dendritic Cells by RIG-I-Stimulating Cytosolic RNA Synthesis of Sendai Virus

(2010) S. Okano et al.   JOURNAL OF IMMUNOLOGY

Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

(2010) K. C. Prins et al.   JOURNAL OF VIROLOGY

Ebola haemorrhagic fever

(2010) Heinz Feldmann et al.   LANCET

A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

(2010) Nicolas Manel et al.   NATURE

Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35

(2010) Daisy W Leung et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide

(2009) H. Jin et al.   JOURNAL OF GENERAL VIROLOGY

Evasion of Interferon Responses by Ebola and Marburg Viruses

(2009) Christopher F. Basler et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Ebola Virus VP35 Antagonizes PKR Activity through Its C-Terminal Interferon Inhibitory Domain

(2009) M. Schumann et al.   JOURNAL OF VIROLOGY

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKK  and TBK-1

(2009) K. C. Prins et al.   JOURNAL OF VIROLOGY

Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression

(2009) C. R. Kimberlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Ebola VP35 interferon inhibitory domain

(2009) D. W. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIG-I activation inhibits ebolavirus replication

(2009) Christina F. Spiropoulou et al.   VIROLOGY

Ebola Zaire Virus Blocks Type I Interferon Production by Exploiting the Host SUMO Modification Machinery

(2009) Tsung-Hsien Chang et al.   PLoS Pathogens

Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression

(2008) Toru Kubota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Whole-Genome Expression Profiling Reveals That Inhibition of Host Innate Immune Response Pathways by Ebola Virus Can Be Reversed by a Single Amino Acid Change in the VP35 Protein

(2008) A. L. Hartman et al.   JOURNAL OF VIROLOGY