Continuous-flow azide–alkyne cycloadditions with an effective bimetallic catalyst and a simple scavenger system

Fine-Tunable Tris(triazolyl)methane Ligands for Copper(I)- Catalyzed Azide-Alkyne Cycloaddition Reactions

(2014) Erhan Ozkal et al.   ADVANCED SYNTHESIS & CATALYSIS

Utilization of a Copper on Iron Catalyst for the Synthesis of Biaryl Systems and Benzoxazines via Oxidative Arylation of Anilide Derivatives

(2014) Zoltán Novák et al.   SYNTHESIS-STUTTGART

Advancements in the mechanistic understanding of the copper-catalyzed azide–alkyne cycloaddition

(2013) Regina Berg et al.   Beilstein Journal of Organic Chemistry

Efficient continuous-flow synthesis of novel 1,2,3-triazole-substituted β-aminocyclohexanecarboxylic acid derivatives with gram-scale production

(2013) Sándor B Ötvös et al.   Beilstein Journal of Organic Chemistry

Flash chemistry: flow chemistry that cannot be done in batch

(2013) Jun-ichi Yoshida et al.   CHEMICAL COMMUNICATIONS

Alkyne-Azide Cycloadditions with Copper Powder in a High-Pressure Continuous-Flow Reactor: High-Temperature Conditions versus the Role of Additives

(2013) Sándor B. Ötvös et al.   Chemistry-An Asian Journal

Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry

(2013) Volker Hessel et al.   ChemSusChem

The role of flow in green chemistry and engineering

(2013) Stephen G. Newman et al.   GREEN CHEMISTRY

Continuous process technology: a tool for sustainable production

(2013) Charlotte Wiles et al.   GREEN CHEMISTRY

Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis

(2013) D. Tyler McQuade et al.   JOURNAL OF ORGANIC CHEMISTRY

Flow Chemistry - A Key Enabling Technology for (Multistep) Organic Synthesis

(2012) Jens Wegner et al.   ADVANCED SYNTHESIS & CATALYSIS

On Being Green: Can Flow Chemistry Help?

(2012) Steven V. Ley   CHEMICAL RECORD

Copper(I)-Catalyzed Azide-Alkyne Cycloadditions in Microflow: Catalyst Activity, High-T Operation, and an Integrated Continuous Copper Scavenging Unit

(2012) Alvaro Carlos Varas et al.   ChemSusChem

Magnetic copper–iron nanoparticles as simple heterogeneous catalysts for the azide–alkyne click reaction in water

(2012) Reuben Hudson et al.   GREEN CHEMISTRY

Cascade Intermolecular Michael Addition–Intramolecular Azide/Internal Alkyne 1,3-Dipolar Cycloaddition Reaction in One Pot

(2012) Rajesh K. Arigela et al.   ORGANIC LETTERS

Copper on Iron: Catalyst and Scavenger for Azide–Alkyne Cycloaddition

(2012) Zoltán Novák et al.   SYNTHESIS-STUTTGART

Deciding Whether To Go with the Flow: Evaluating the Merits of Flow Reactors for Synthesis

(2011) Ryan L. Hartman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis

(2011) Poovan Shanmugavelan et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Ten key issues in modern flow chemistry

(2011) Jens Wegner et al.   CHEMICAL COMMUNICATIONS

“Clicking” on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures

(2011) Kristian Kempe et al.   CHEMICAL SOCIETY REVIEWS

10 Years of Click Chemistry: Synthesis and Applications of Ferrocene-Derived Triazoles

(2011) Venkataraman Ganesh et al.   Chemistry-An Asian Journal

Click to Join Peptides/Proteins Together

(2011) Xuechen Li   Chemistry-An Asian Journal

Click Chemistry: 1,2,3-Triazoles as Pharmacophores

(2011) Sandip G. Agalave et al.   Chemistry-An Asian Journal

1,2,3-Triazoles in Peptidomimetic Chemistry

(2011) Daniel Sejer Pedersen et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Continuous flow reactors: a perspective

(2011) Charlotte Wiles et al.   GREEN CHEMISTRY

Acid–Base Jointly Promoted Copper(I)-Catalyzed Azide–Alkyne Cycloaddition

(2011) Changwei Shao et al.   JOURNAL OF ORGANIC CHEMISTRY

Ultrasound-assisted click chemistry in continuous flow

(2011) Noah P. Tu et al.   MOLECULAR DIVERSITY

A fully automated, multistep flow synthesis of 5-amino-4-cyano-1,2,3-triazoles

(2011) Catherine J. Smith et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fusing Triazoles: Toward Extending Aromaticity

(2011) Michal Juríček et al.   ORGANIC LETTERS

Synthesis of 5-Iodo-1,2,3-triazole-Containing Macrocycles Using Copper Flow Reactor Technology

(2011) Andrew R. Bogdan et al.   ORGANIC LETTERS

Fast Scale-Up Using Microreactors: Pyrrole Synthesis from Micro to Production Scale

(2011) Pieter J. Nieuwland et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Covalently immobilized tris(triazolyl)methanol–Cu(i) complexes: highly active and recyclable catalysts for CuAAC reactions

(2011) Erhan Ozkal et al.   Catalysis Science & Technology

Copper(I) Acetate: A Structurally Simple but Highly Efficient Dinuclear Catalyst for Copper-Catalyzed Azide-Alkyne Cycloaddition

(2010) Changwei Shao et al.   ADVANCED SYNTHESIS & CATALYSIS

Mechanistic Insights into Copper(I)-Catalyzed Azide-Alkyne Cycloadditions using Continuous Flow Conditions

(2010) Michael Fuchs et al.   ADVANCED SYNTHESIS & CATALYSIS

Scale-up concept of single-channel microreactors from process development to industrial production

(2010) Norbert Kockmann et al.   CHEMICAL ENGINEERING JOURNAL

Click chemistry generates privileged CH hydrogen-bonding triazoles: the latest addition to anion supramolecular chemistry

(2010) Yuran Hua et al.   CHEMICAL SOCIETY REVIEWS

Efficient Access to New Chemical Space Through Flow-Construction of Druglike Macrocycles Through Copper-Surface-Catalyzed Azide-Alkyne Cycloaddition Reactions

(2010) Andrew R. Bogdan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Green and Sustainable Chemical Synthesis Using Flow Microreactors

(2010) Jun-ichi Yoshida et al.   ChemSusChem

A highly efficient copper(i) catalyst for the 1,3-dipolar cycloaddition of azides with terminal and 1-iodoalkynes in water: regioselective synthesis of 1,4-disubstituted and 1,4,5-trisubstituted 1,2,3-triazoles

(2010) Joaquín García-Álvarez et al.   GREEN CHEMISTRY

Carboxylic Acid-Promoted Copper(I)-Catalyzed Azide−Alkyne Cycloaddition

(2010) Changwei Shao et al.   JOURNAL OF ORGANIC CHEMISTRY

Oxidoreductive coupling of thiols with aryl halides catalyzed by copper on iron

(2010) Szabolcs Kovács et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Use of Copper Flow Reactor Technology for the Continuous Synthesis of 1,4-Disubstituted 1,2,3-Triazoles

(2009) Andrew R. Bogdan et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper(I)-Catalyzed Cycloaddition of Organic Azides and 1-Iodoalkynes

(2009) Jason E. Hein et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly active copper-catalysts for azide-alkynecycloaddition

(2009) Zsombor Gonda et al.   DALTON TRANSACTIONS

Cu-Catalyzed Azide−Alkyne Cycloaddition

(2008) Morten Meldal et al.   CHEMICAL REVIEWS

Click Chemistry and Medicinal Chemistry: A Case of “Cyclo-Addiction”

(2008) A. D. Moorhouse et al.   ChemMedChem