Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding

A family of DNA aptamers with varied duplex region length that forms complexes with thrombin and prothrombin

(2015) V.A. Spiridonova et al.   FEBS LETTERS

Duplex stem-loop-containing quadruplex motifs in the human genome: a combined genomic and structural study

(2015) K. W. Lim et al.   NUCLEIC ACIDS RESEARCH

Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides

(2015) Nan Zhang et al.   Chemical Science

Joining of Multiple Duplex Stems at a Single Quadruplex Loop

(2014) Kah Wai Lim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex

(2014) Irene Russo Krauss et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Duplex–quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer

(2013) Irene Russo Krauss et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis of DNA Quadruplex-Duplex Junction Formation

(2013) Kah Wai Lim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Thermal Stability of DNA Quadruplex–Duplex Hybrids

(2013) Kah Wai Lim et al.   BIOCHEMISTRY

Meeting report: Fourth international meeting on G-quadruplex Nucleic Acids (Singapore, July 1–4, 2013)

(2013) Jean-Louis Mergny   BIOCHIMIE

Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer

(2013) Andrea Pica et al.   FEBS Journal

G-Quadruplex Structures in the Human Genome as Novel Therapeutic Targets

(2013) Joanna Bidzinska et al.   MOLECULES

Coexistence of G-quadruplex and duplex domains within the secondary structure of 31-mer DNA thrombin-binding aptamer

(2012) N.G. Dolinnaya et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

NMR spectroscopy of G-quadruplexes

(2012) Michael Adrian et al.   METHODS

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity

(2012) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

COCOMAPS: a web application to analyze and visualize contacts at the interface of biomolecular complexes

(2011) A. Vangone et al.   BIOINFORMATICS

Characteristics of a New DNA Aptamer, Direct Inhibitor of Thrombin

(2011) A. V. Mazurov et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

(2011) Yan Xu   CHEMICAL SOCIETY REVIEWS

Thrombin–aptamer recognition: a revealed ambiguity

(2011) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystallization and preliminary X-ray analysis of the complex of human α-thrombin with a modified thrombin-binding aptamer

(2010) Irene Russo Krauss et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Consecutive Formation of G-Quadruplexes in Human Telomeric-Overhang DNA: A Protective Capping Structure for Telomere Ends

(2009) Yan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Chemical Biology of Aptamers

(2009) Günter Mayer   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleic Acid Aptamers Based on the G-Quadruplex Structure: Therapeutic and Diagnostic Potential

(2009) B. Gatto et al.   CURRENT MEDICINAL CHEMISTRY

Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer

(2009) Stephen Neidle   FEBS Journal

Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regions

(2008) Yong Qin et al.   BIOCHIMIE

3DNA: a versatile, integrated software system for the analysis, rebuilding and visualization of three-dimensional nucleic-acid structures

(2008) Xiang-Jun Lu et al.   Nature Protocols

The triple helix: 50 years later, the outcome

(2008) M. Duca et al.   NUCLEIC ACIDS RESEARCH

PSAIA - Protein Structure and Interaction Analyzer

(2008) Josip Mihel et al.   BMC STRUCTURAL BIOLOGY