High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity

Crystal structure of a c-kit promoter quadruplex reveals the structural role of metal ions and water molecules in maintaining loop conformation

(2012) D. Wei et al.   NUCLEIC ACIDS RESEARCH

Magnetic relaxation switch and colorimetric detection of thrombin using aptamer-functionalized gold-coated iron oxide nanoparticles

(2011) Guohai Liang et al.   ANALYTICA CHIMICA ACTA

Loop residues of thrombin-binding DNA aptamer impact G-quadruplex stability and thrombin binding

(2011) Satoru Nagatoishi et al.   BIOCHIMIE

Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process

(2011) Roman V. Reshetnikov et al.   NUCLEIC ACIDS RESEARCH

Thrombin–aptamer recognition: a revealed ambiguity

(2011) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

Crystallization and preliminary X-ray analysis of the complex of human α-thrombin with a modified thrombin-binding aptamer

(2010) Irene Russo Krauss et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

On-Chip Aptamer-Based Sandwich Assay for Thrombin Detection Employing Magnetic Beads and Quantum Dots

(2010) Yolanda H. Tennico et al.   ANALYTICAL CHEMISTRY

Structural Dynamics of Thrombin-Binding DNA Aptamer d(GGTTGGTGTGGTTGG) Quadruplex DNA Studied by Large-Scale Explicit Solvent Simulations

(2010) Roman Reshetnikov et al.   Journal of Chemical Theory and Computation

Mass spectrometric studies of alkali metal ion binding on thrombin-binding aptamer DNA

(2010) Eun Sun Hong et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer

(2010) Anna Pasternak et al.   NUCLEIC ACIDS RESEARCH

Nucleic acid aptamers as antithrombotic agents: Opportunities in extracellular therapeutics

(2010) Thomas Povsic et al.   THROMBOSIS AND HAEMOSTASIS

Aptamer evolution for array-based diagnostics

(2009) Mark Platt et al.   ANALYTICAL BIOCHEMISTRY

Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions

(2009) Marina Zaitseva et al.   BIOPHYSICAL CHEMISTRY

Differential Regulation of Protein Subdomain Activity with Caged Bivalent Ligands

(2009) Günter Mayer et al.   CHEMBIOCHEM

Nucleic Acid Aptamers Based on the G-Quadruplex Structure: Therapeutic and Diagnostic Potential

(2009) B. Gatto et al.   CURRENT MEDICINAL CHEMISTRY

Combinatorial Synthesis of Thrombin-Binding Aptamers Containing iso-Guanine

(2009) Subba Rao Nallagatla et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Conformationally rigid nucleoside probes help understand the role of sugar pucker and nucleobase orientation in the thrombin-binding aptamer

(2009) Hisao Saneyoshi et al.   NUCLEIC ACIDS RESEARCH

Cation localization and movement within DNA thrombin binding aptamer in solution

(2009) Marko Trajkovski et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Effect of Locked-Nucleic Acid on a Biologically Active G-Quadruplex. A Structure-Activity Relationship of the Thrombin Aptamer

(2008) Laura Bonifacio et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stability and kinetics of G-quadruplex structures

(2008) A. N. Lane et al.   NUCLEIC ACIDS RESEARCH

Stability and Binding Properties of a Modified Thrombin Binding Aptamer

(2007) Bruno Pagano et al.   BIOPHYSICAL JOURNAL