PNPLA3 variant M148 causes resistance to starvation-mediated lipid droplet autophagy in human hepatocytes

The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation

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Patatin-like phospholipase domain-containing protein 3 (PNPLA3): A potential role in the association between liver disease and bipolar disorder

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iLIR database: A web resource for LIR motif-containing proteins in eukaryotes

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iLIR

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Interactions between Autophagy Receptors and Ubiquitin-like Proteins Form the Molecular Basis for Selective Autophagy

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Cargo recognition and trafficking in selective autophagy

(2014) Alexandra Stolz et al.   NATURE CELL BIOLOGY

PNPLA3/adiponutrin functions in lipid droplet formation

(2013) Zeina Chamoun et al.   BIOLOGY OF THE CELL

Association of the I148M/PNPLA3 variant with elevated alanine transaminase levels in normal-weight and overweight/obese Mexican children

(2013) Elena Larrieta-Carrasco et al.   GENE

Adiponutrin Functions as a Nutritionally Regulated Lysophosphatidic Acid Acyltransferase

(2012) Manju Kumari et al.   Cell Metabolism

Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese

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Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

(2012) N. Jaber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease

(2011) Yongcheng Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Common polymorphism in the PNPLA3/adiponutrin gene confers higher risk of cirrhosis and liver damage in alcoholic liver disease

(2011) Eric Trépo et al.   JOURNAL OF HEPATOLOGY

Autophagic Degradation of Mitochondria in White Adipose Tissue Differentiation

(2010) Scott J. Goldman et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of PNPLA3 on Liver Fat and Metabolic Profile in Hispanic Children and Adolescents

(2010) M. I. Goran et al.   DIABETES

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

(2010) Yaron Rotman et al.   HEPATOLOGY

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

(2009) Viktor I. Korolchuk et al.   FEBS LETTERS

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS