iLIR database: A web resource for LIR motif-containing proteins in eukaryotes

Analysis of the native conformation of the LIR/AIM motif in the Atg8/LC3/GABARAP-binding proteins

(2015) Hana Popelka et al.   Autophagy

XIAP and cIAP1 amplifications induce Beclin 1-dependent autophagy through NFκB activation

(2015) Fang Lin et al.   HUMAN MOLECULAR GENETICS

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

(2014) Chinmoy Sarkar et al.   Autophagy

FLCN, a novel autophagy component, interacts with GABARAP and is regulated by ULK1 phosphorylation

(2014) Elaine A Dunlop et al.   Autophagy

iLIR

(2014) Ioanna Kalvari et al.   Autophagy

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes

(2014) Meng-meng Fu et al.   DEVELOPMENTAL CELL

Endorepellin Evokes Autophagy in Endothelial Cells

(2014) Chiara Poluzzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polycystin-1 Negatively Regulates Polycystin-2 Expression via the Aggresome/Autophagosome Pathway

(2014) Valeriu Cebotaru et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

iASPP is a novel autophagy inhibitor in keratinocytes

(2014) A. Chikh et al.   JOURNAL OF CELL SCIENCE

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Histone Deacetylase HDAC4 Promotes Gastric Cancer SGC-7901 Cells Progression via p21 Repression

(2014) Zhen-Hua Kang et al.   PLoS One

Potential function for the Huntingtin protein as a scaffold for selective autophagy

(2014) Joseph Ochaba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1 is degraded through the N-end rule pathway

(2013) Koji Yamano et al.   Autophagy

BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production

(2013) Yunha Kim et al.   Autophagy

Cellular Mechanotransduction Relies on Tension-Induced and Chaperone-Assisted Autophagy

(2013) Anna Ulbricht et al.   CURRENT BIOLOGY

The role of ‘eat-me’ signals and autophagy cargo receptors in innate immunity

(2013) Keith B. Boyle et al.   CURRENT OPINION IN MICROBIOLOGY

XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling

(2013) Xing Huang et al.   EMBO JOURNAL

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

(2013) Katy J Petherick et al.   EMBO JOURNAL

Reversible Acetylation Regulates Salt-inducible Kinase (SIK2) and Its Function in Autophagy

(2013) Fu-Chia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

The LC3 interactome at a glance

(2013) P. Wild et al.   JOURNAL OF CELL SCIENCE

Epigenetic Regulation of Autophagy by the Methyltransferase G9a

(2013) A. Artal-Martinez de Narvajas et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy promotes primary ciliogenesis by removing OFD1 from centriolar satellites

(2013) Zaiming Tang et al.   NATURE

FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade

(2013) Shafi Kuchay et al.   NATURE CELL BIOLOGY

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

(2013) Y. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy

(2013) T. Tasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Decorin causes autophagy in endothelial cells via Peg3

(2013) S. Buraschi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis and favors glioblastoma resistance to etoposide

(2013) D Biasoli et al.   Cell Death & Disease

Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy

(2012) Mireia Niso-Santano et al.   Autophagy

TLR2-dependent selective autophagy regulates NF-κB lysosomal degradation in hepatoma-derived M2 macrophage differentiation

(2012) C-P Chang et al.   CELL DEATH AND DIFFERENTIATION

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

(2012) Claudine Kraft et al.   EMBO JOURNAL

Selective Autophagy of the Adaptor Protein Bcl10 Modulates T Cell Receptor Activation of NF-κB

(2012) Suman Paul et al.   IMMUNITY

ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex

(2012) Endalkachew Ashenafi Alemu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Autophagy-related Protein Kinase Atg1 Interacts with the Ubiquitin-like Protein Atg8 via the Atg8 Family Interacting Motif to Facilitate Autophagosome Formation

(2012) Hitoshi Nakatogawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule-associated Protein/Microtubule Affinity-regulating Kinase 4 (MARK4) Is a Negative Regulator of the Mammalian Target of Rapamycin Complex 1 (mTORC1)

(2012) Li Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab GTPase-Activating Proteins in Autophagy: Regulation of Endocytic and Autophagy Pathways by Direct Binding to Human ATG8 Modifiers

(2012) D. Popovic et al.   MOLECULAR AND CELLULAR BIOLOGY

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Unknown

(2012) Yinzhong Zhang et al.   MOLECULAR MEDICINE

Autophagy

(2011) Jane Yu et al.   Autophagy

Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)

(2011) Peiyuan Li et al.   CANCER LETTERS

p65/RelA-Ser529 NF-κB Subunit Phosphorylation Induces Autophagic Astroglial Death (Clasmatodendrosis) Following Status Epilepticus

(2011) Hea Jin Ryu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

GABARAPL1 Negatively Regulates Wnt/β-catenin Signaling by Mediating Dvl2 Degradation through the Autophagy Pathway

(2011) Yanquan Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Autophagosomal IκBα Degradation Plays a Role in the Long Term Control of Tumor Necrosis Factor-α-induced Nuclear Factor-κB (NF-κB) Activity

(2011) Amy Colleran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microtubule-associated Protein 1S (MAP1S) Bridges Autophagic Components with Microtubules and Mitochondria to Affect Autophagosomal Biogenesis and Degradation

(2011) Rui Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals

(2011) Mikel Garcia-Marcos et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Atg8: an autophagy-related ubiquitin-like protein family

(2011) Tomer Shpilka et al.   GENOME BIOLOGY

The RB-E2F1 Pathway Regulates Autophagy

(2010) H. Jiang et al.   CANCER RESEARCH

BRCA1 negatively regulates formation of autophagic vacuoles in MCF-7 breast cancer cells

(2010) Juan M. Esteve et al.   EXPERIMENTAL CELL RESEARCH

Atg8-family interacting motif crucial for selective autophagy

(2010) Nobuo N. Noda et al.   FEBS LETTERS

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

(2010) C. Rothenberg et al.   HUMAN MOLECULAR GENETICS

Autophagy Facilitates IFN-γ-induced Jak2-STAT1 Activation and Cellular Inflammation

(2010) Yu-Ping Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy-related Protein 8 (Atg8) Family Interacting Motif in Atg3 Mediates the Atg3-Atg8 Interaction and Is Crucial for the Cytoplasm-to-Vacuole Targeting Pathway

(2010) Masaya Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport

(2010) Serhiy Pankiv et al.   JOURNAL OF CELL BIOLOGY

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation

(2010) Chan Gao et al.   NATURE CELL BIOLOGY

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy

(2009) Melanie Schwarten et al.   Autophagy

Low Concentrations of Diindolylmethane, a Metabolite of Indole-3-Carbinol, Protect against Oxidative Stress in a BRCA1-Dependent Manner

(2009) S. Fan et al.   CANCER RESEARCH

MYC Activity Mitigates Response to Rapamycin in Prostate Cancer through Eukaryotic Initiation Factor 4E-Binding Protein 1-Mediated Inhibition of Autophagy

(2009) B. S. Balakumaran et al.   CANCER RESEARCH

Lipophagy: Selective Catabolism Designed for Lipids

(2009) Hilla Weidberg et al.   DEVELOPMENTAL CELL

The structure of Atg4B–LC3 complex reveals the mechanism of LC3 processing and delipidation during autophagy

(2009) Kenji Satoo et al.   EMBO JOURNAL

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

(2009) Elsa-Noah N'Diaye et al.   EMBO REPORTS

Nix is a selective autophagy receptor for mitochondrial clearance

(2009) Ivana Novak et al.   EMBO REPORTS

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Progressive Purkinje Cell Degeneration in tambaleante Mutant Mice Is a Consequence of a Missense Mutation in HERC1 E3 Ubiquitin Ligase

(2009) Tomoji Mashimo et al.   PLoS Genetics

Structural Basis for Sorting Mechanism of p62 in Selective Autophagy

(2008) Yoshinobu Ichimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY