Pro-aggregant Tau impairs mossy fiber plasticity due to structural changes and Ca++ dysregulation

Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer’s disease model

(2013) Manuela Polydoro et al.   ACTA NEUROPATHOLOGICA

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

(2013) J. K. Holth et al.   JOURNAL OF NEUROSCIENCE

Antisense Reduction of Tau in Adult Mice Protects against Seizures

(2013) S. L. DeVos et al.   JOURNAL OF NEUROSCIENCE

Microtubule-associated protein tau is essential for long-term depression in the hippocampus

(2013) T. Kimura et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Deciphering Alzheimer Disease

(2013) D. Selkoe et al.   Cold Spring Harbor Perspectives in Medicine

Cognitive defects are reversible in inducible mice expressing pro-aggregant full-length human Tau

(2012) Ann Van der Jeugd et al.   ACTA NEUROPATHOLOGICA

NMDA receptor dysfunction contributes to impaired brain-derived neurotrophic factor-induced facilitation of hippocampal synaptic transmission in a Tau transgenic model

(2012) Sylvie Burnouf et al.   AGING CELL

Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing

(2012) Shanting Zhao et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Making the Brain Glow: In Vivo Bioluminescence Imaging to Study Neurodegeneration

(2012) Katja Hochgräfe et al.   MOLECULAR NEUROBIOLOGY

Cascade of tau toxicity in inducible hippocampal brain slices and prevention by aggregation inhibitors

(2012) Lars Messing et al.   NEUROBIOLOGY OF AGING

Human P301L-Mutant Tau Expression in Mouse Entorhinal-Hippocampal Network Causes Tau Aggregation and Presynaptic Pathology but No Cognitive Deficits

(2012) Julie A. Harris et al.   PLoS One

Neuropathological background of phenotypical variability in frontotemporal dementia

(2011) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

(2011) A. Sydow et al.   JOURNAL OF NEUROSCIENCE

Hippocampal mossy fiber long-term depression in Grm2/3 double knockout mice

(2011) Louisa Lyon et al.   SYNAPSE

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Properties of CA3 Dendritic Excrescences in Alzheimers Disease

(2010) K. Tsamis et al.   Current Alzheimer Research

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Hippocampal tauopathy in tau transgenic mice coincides with impaired hippocampus-dependent learning and memory, and attenuated late-phase long-term depression of synaptic transmission

(2010) Ann Van der Jeugd et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Tau protein and tau aggregation inhibitors

(2010) Bruno Bulic et al.   NEUROPHARMACOLOGY

Frequency Facilitation at Mossy Fiber-CA3 Synapses of Freely Behaving Rats Contributes to the Induction of Persistent LTD via an Adenosine-A1 Receptor-Regulated Mechanism

(2009) H. Hagena et al.   CEREBRAL CORTEX

Structural and functional changes in tau mutant mice neurons are not linked to the presence of NFTs

(2009) A.B. Rocher et al.   EXPERIMENTAL NEUROLOGY

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

(2009) Geraldine Butler et al.   NATURE

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

The Potential for -Structure in the Repeat Domain of Tau Protein Determines Aggregation, Synaptic Decay, Neuronal Loss, and Coassembly with Endogenous Tau in Inducible Mouse Models of Tauopathy

(2008) M.-M. Mocanu et al.   JOURNAL OF NEUROSCIENCE

Role of Glutamate Autoreceptors at Hippocampal Mossy Fiber Synapses

(2008) Hyung-Bae Kwon et al.   NEURON

Clinical and pathological features of an Alzheimer's disease patient with the MAPT ΔK280 mutation

(2007) Parastoo Momeni et al.   NEUROBIOLOGY OF AGING