Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits

Genetic Architecture of MicroRNA Expression: Implications for the Transcriptome and Complex Traits

(2012) Eric R. Gamazon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

miRNA arm selection and isomiR distribution in gastric cancer

(2012) Sung-Chou Li et al.   BMC GENOMICS

MicroRNA-204 increases sensitivity of neuroblastoma cells to cisplatin and is associated with a favourable clinical outcome

(2012) J Ryan et al.   BRITISH JOURNAL OF CANCER

MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo

(2012) R.-R. Cui et al.   CARDIOVASCULAR RESEARCH

MicroRNAs in Insulin Resistance and Obesity

(2012) Michael D. Williams et al.   Experimental Diabetes Research

MicroRNAs in adipose tissue: their role in adipogenesis and obesity

(2012) C Hilton et al.   INTERNATIONAL JOURNAL OF OBESITY

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Differential Expression of MicroRNAs in Adipose Tissue after Long-Term High-Fat Diet-Induced Obesity in Mice

(2012) Dionysios V. Chartoumpekis et al.   PLoS One

miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

(2012) S. Djuranovic et al.   SCIENCE

Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish

(2012) A. A. Bazzini et al.   SCIENCE

Extent, Causes, and Consequences of Small RNA Expression Variation in Human Adipose Tissue

(2012) Leopold Parts et al.   PLoS Genetics

Dissecting the regulatory architecture of gene expression QTLs

(2012) Daniel J Gaffney et al.   GENOME BIOLOGY

Sex differences in microRNA regulation of gene expression: no smoke, just miRs

(2012) Christopher P Morgan et al.   Biology of Sex Differences

Sirtuin 1 in lipid metabolism and obesity

(2011) Thaddeus T. Schug et al.   ANNALS OF MEDICINE

The Role of MicroRNAs in Cholesterol Efflux and Hepatic Lipid Metabolism

(2011) Kathryn J. Moore et al.   Annual Review of Nutrition

microRNAs in the Regulation of Adipogenesis and Obesity

(2011) R. A. McGregor et al.   CURRENT MOLECULAR MEDICINE

MicroRNA evolution by arm switching

(2011) Sam Griffiths-Jones et al.   EMBO REPORTS

Sirt1 and mir-9 expression is regulated during glucose-stimulated insulin secretion in pancreatic β-islets

(2011) Deepti Ramachandran et al.   FEBS Journal

Barcoding bias in high-throughput multiplex sequencing of miRNA

(2011) S. Alon et al.   GENOME RESEARCH

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers

(2011) H. M. Heneghan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Role for miR-204 in human pulmonary arterial hypertension

(2011) Audrey Courboulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-29a and miR-29b Contribute to Pancreatic  -Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1)

(2011) T. J. Pullen et al.   MOLECULAR AND CELLULAR BIOLOGY

Association of ACACB polymorphisms with obesity and diabetes

(2011) J.A. Riancho et al.   MOLECULAR GENETICS AND METABOLISM

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

TarBase 6.0: capturing the exponential growth of miRNA targets with experimental support

(2011) T. Vergoulis et al.   NUCLEIC ACIDS RESEARCH

The Effect of ACACB cis-Variants on Gene Expression and Metabolic Traits

(2011) Lijun Ma et al.   PLoS One

MicroRNA Expression in Abdominal and Gluteal Adipose Tissue Is Associated with mRNA Expression Levels and Partly Genetically Driven

(2011) Mattias Rantalainen et al.   PLoS One

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling

(2011) A. Davalos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-486-5p Induces Replicative Senescence of Human Adipose Tissue-Derived Mesenchymal Stem Cells and Its Expression Is Controlled by High Glucose

(2011) Yeon Jeong Kim et al.   STEM CELLS AND DEVELOPMENT

MicroRNAs and their isomiRs function cooperatively to target common biological pathways

(2011) Nicole Cloonan et al.   GENOME BIOLOGY

Small RNA sequencing reveals miR-642a-3p as a novel adipocyte-specific microRNA and miR-30 as a key regulator of human adipogenesis

(2011) Laure-Emmanuelle Zaragosi et al.   GENOME BIOLOGY

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

MicroRNA-223 regulates Glut4 expression and cardiomyocyte glucose metabolism

(2010) Han Lu et al.   CARDIOVASCULAR RESEARCH

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Identification of cis- and trans-regulatory variation modulating microRNA expression levels in human fibroblasts

(2010) C. Borel et al.   GENOME RESEARCH

RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression

(2010) E. Lalonde et al.   GENOME RESEARCH

ACC2gene polymorphisms, metabolic syndrome, and gene-nutrient interactions with dietary fat

(2010) Catherine M. Phillips et al.   JOURNAL OF LIPID RESEARCH

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

MicroRNA profiling: separating signal from noise

(2010) Monya Baker   NATURE METHODS

miRBase: integrating microRNA annotation and deep-sequencing data

(2010) A. Kozomara et al.   NUCLEIC ACIDS RESEARCH

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

(2009) Brandi N Davis et al.   Cell Communication and Signaling

Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men

(2009) A. Stancakova et al.   DIABETES

MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

(2009) H. Xie et al.   DIABETES

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

Limitations and possibilities of small RNA digital gene expression profiling

(2009) Sam E V Linsen et al.   NATURE METHODS

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data

(2009) Nuno L. Barbosa-Morais et al.   NUCLEIC ACIDS RESEARCH

Role of microRNAs in obesity and the metabolic syndrome

(2009) H. M. Heneghan et al.   Obesity Reviews

ACC2 Is Expressed at High Levels Human White Adipose and Has an Isoform with a Novel N-Terminus

(2009) John C. Castle et al.   PLoS One

Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet

(2008) Rieko Takanabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

(2008) R. D. Morin et al.   GENOME RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

miRecords: an integrated resource for microRNA-target interactions

(2008) F. Xiao et al.   NUCLEIC ACIDS RESEARCH

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA