Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

HLA*IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes

(2011) Alexander T. Dilthey et al.   BIOINFORMATICS

The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane

(2011) E. D. Elstak et al.   BLOOD

Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex

(2011) C. Vandiedonck et al.   GENOME RESEARCH

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes

(2011) Kerrin S Small et al.   NATURE GENETICS

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

(2011) David M Evans et al.   NATURE GENETICS

The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study

(2011) Alexandra C. Nica et al.   PLoS Genetics

Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA

(2011) Rudolf S. N. Fehrmann et al.   PLoS Genetics

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

Glycosylation regulates NK cell-mediated effector function through PI3K pathway

(2010) V. Benson et al.   INTERNATIONAL IMMUNOLOGY

The Role of the Transcription Factor CREB in Immune Function

(2010) A. Y. Wen et al.   JOURNAL OF IMMUNOLOGY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1

(2010) Amy Strange et al.   NATURE GENETICS

Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility

(2010) Tanja Zeller et al.   PLoS One

p53-mediated apoptosis requires inositol hexakisphosphate kinase-2

(2010) M. A. Koldobskiy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics

Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

(2010) Alexandra C. Nica et al.   PLoS Genetics

CARD9 Signaling in the Innate Immune Response

(2009) Jürgen Ruland   Annals of the New York Academy of Sciences

A regulatory SNP at position −899 in CDKN1A is associated with systemic lupus erythematosus and lupus nephritis

(2009) K Kim et al.   GENES AND IMMUNITY

Geographical genomics of human leukocyte gene expression variation in southern Morocco

(2009) Youssef Idaghdour et al.   NATURE GENETICS

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C

(2009) Rasmi Thomas et al.   NATURE GENETICS

Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways

(2009) Rajan P Nair et al.   NATURE GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis

(2009) J. E. Landers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

(2009) et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner

(2009) A. S. Dimas et al.   SCIENCE

Expression Quantitative Trait Loci Are Highly Sensitive to Cellular Differentiation State

(2009) Alice Gerrits et al.   PLoS Genetics

Tissue Effect on Genetic Control of Transcript Isoform Variation

(2009) Tony Kwan et al.   PLoS Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

A Statistical Method for Predicting Classical HLA Alleles from SNP Data

(2008) Stephen Leslie et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13

(2008) Vincent Plagnol et al.   BIOSTATISTICS

Critical but divergent roles for CD62L and CD44 in directing blood monocyte trafficking in vivo during inflammation

(2008) H. Xu et al.   BLOOD

A Novel Susceptibility Locus for Type 1 Diabetes on Chr12q13 Identified by a Genome-Wide Association Study

(2008) H. Hakonarson et al.   DIABETES

Genomewide Association Study of an AIDS‐Nonprogression Cohort Emphasizes the Role Played byHLAGenes (ANRS Genomewide Association Study 02)

(2008) Sophie Limou et al.   JOURNAL OF INFECTIOUS DISEASES

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

(2008) Ying Liu et al.   PLoS Genetics