Interaction of tumor cells and lymphatic vessels in cancer progression

Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Tumor-Induced Lymph Flow

(2015) Alanna Ruddell et al.   NEOPLASIA

Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor

(2011) W. Zheng et al.   BLOOD

Cancer statistics, 2011

(2011) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CCBE1 Is Essential for Mammalian Lymphatic Vascular Development and Enhances the Lymphangiogenic Effect of Vascular Endothelial Growth Factor-C In Vivo

(2011) Frank L. Bos et al.   CIRCULATION RESEARCH

Proteolytic processing of vascular endothelial growth factor-D is essential for its capacity to promote the growth and spread of cancer

(2011) Nicole C. Harris et al.   FASEB JOURNAL

Ets family members induce lymphangiogenesis through physical and functional interaction with Prox1

(2011) Y. Yoshimatsu et al.   JOURNAL OF CELL SCIENCE

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

(2011) Dontscho Kerjaschki et al.   JOURNAL OF CLINICAL INVESTIGATION

Prognostic impact and therapeutic implications of sentinel lymph node micro-metastases in early-stage breast cancer patients

(2011) Carsten T. Viehl et al.   JOURNAL OF SURGICAL ONCOLOGY

Unique patterns of metastases in common and rare types of malignancy

(2011) Stanley P.L. Leong et al.   JOURNAL OF SURGICAL ONCOLOGY

Impact of nodal status and tumor burden in sentinel lymph nodes on the clinical outcomes of cancer patients

(2011) Stanley P.L. Leong et al.   JOURNAL OF SURGICAL ONCOLOGY

Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer

(2011) Hanseul Yang et al.   Molecular Cancer

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

(2011) Tuomas Tammela et al.   NATURE CELL BIOLOGY

Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents Metastasis

(2011) T. Tammela et al.   Science Translational Medicine

Locoregional Spread of Cutaneous Melanoma: Sonography Findings

(2010) Orlando Catalano et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Platelets

(2010) Cara C. Bertozzi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin

(2010) L. N. Cueni et al.   BLOOD

Structural determinants of vascular endothelial growth factor-D receptor binding and specificity

(2010) V.-M. Leppanen et al.   BLOOD

An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells

(2010) J. Kang et al.   BLOOD

Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling

(2010) C. C. Bertozzi et al.   BLOOD

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

In vivo Imaging of Inflammation- and Tumor-Induced Lymph Node Lymphangiogenesis by Immuno-Positron Emission Tomography

(2010) V. Mumprecht et al.   CANCER RESEARCH

CXCR4 Signaling Regulates Metastasis of Chemoresistant Melanoma Cells by a Lymphatic Metastatic Niche

(2010) M. Kim et al.   CANCER RESEARCH

Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green

(2010) S. T. Proulx et al.   CANCER RESEARCH

VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis

(2010) Luqing Zhang et al.   CELL RESEARCH

Endothelial Cell Adhesion to the Extracellular Matrix Induces c-Src–Dependent VEGFR-3 Phosphorylation Without the Activation of the Receptor Intrinsic Kinase Activity

(2010) Federico Galvagni et al.   CIRCULATION RESEARCH

Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation

(2010) E. J. Gordon et al.   DEVELOPMENT

Dynamic, M2-Like Remodeling Phenotypes of CD11c+ Adipose Tissue Macrophages During High-Fat Diet-Induced Obesity in Mice

(2010) M. E. Shaul et al.   DIABETES

VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts

(2010) Ingrid Nilsson et al.   EMBO JOURNAL

Estimates of cancer incidence and mortality in Europe in 2008

(2010) J. Ferlay et al.   EUROPEAN JOURNAL OF CANCER

Tbx1 regulatesVegfr3and is required for lymphatic vessel development

(2010) Li Chen et al.   JOURNAL OF CELL BIOLOGY

Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3

(2010) Yunling Xu et al.   JOURNAL OF CELL BIOLOGY

The Human Cutaneous Squamous Cell Carcinoma Microenvironment Is Characterized by Increased Lymphatic Density and Enhanced Expression of Macrophage-Derived VEGF-C

(2010) Dariush Moussai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

A Role for All-Trans-Retinoic Acid in the Early Steps of Lymphatic Vasculature Development

(2010) Daniela Marino et al.   JOURNAL OF VASCULAR RESEARCH

Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial

(2010) David N Krag et al.   LANCET ONCOLOGY

Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre-Clinical Models

(2010) DAI FUKUMURA et al.   MICROCIRCULATION

Role of CD11b + Macrophages in Intraperitoneal Lipopolysaccharide-Induced Aberrant Lymphangiogenesis and Lymphatic Function in the Diaphragm

(2009) Kyung Eun Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

From tumor lymphangiogenesis to lymphvascular niche

(2009) Satoshi Hirakawa   CANCER SCIENCE

Activated Forms of VEGF-C and VEGF-D Provide Improved Vascular Function in Skeletal Muscle

(2009) Andrey Anisimov et al.   CIRCULATION RESEARCH

Immunological functions of hyaluronan and its receptors in the lymphatics

(2009) David G. Jackson   IMMUNOLOGICAL REVIEWS

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels

(2009) Holger Pflicke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

Lymphatic Precollectors Contain a Novel, Specialized Subpopulation of Podoplaninlow, CCL27-Expressing Lymphatic Endothelial Cells

(2008) Nikolaus Wick et al.   AMERICAN JOURNAL OF PATHOLOGY

Lymphatic Vasculature Development

(2008) Guillermo Oliver et al.   Annals of the New York Academy of Sciences

VEGFR1 Tyrosine Kinase Signaling Promotes Lymphangiogenesis as Well as Angiogenesis Indirectly via Macrophage Recruitment

(2008) Masato Murakami et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Blocking Neuropilin-2 Function Inhibits Tumor Cell Metastasis

(2008) Maresa Caunt et al.   CANCER CELL

Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis

(2008) J. B. Burton et al.   CANCER RESEARCH

Tumor lymphangiogenesis and melanoma metastasis

(2008) Matthias Rinderknecht et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Deletion of Vascular Endothelial Growth Factor C (VEGF-C) and VEGF-D Is Not Equivalent to VEGF Receptor 3 Deletion in Mouse Embryos

(2008) P. Haiko et al.   MOLECULAR AND CELLULAR BIOLOGY

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE