Non-canonical NF-κB signalling and ETS1/2 cooperatively drive C250T mutant TERT promoter activation

Quantitative assessment of telomerase components in cancer cell lines

(2015) Semih Can Akıncılar et al.   FEBS LETTERS

Structural Insights into the Autoregulation and Cooperativity of the Human Transcription Factor Ets-2

(2015) Joseph A Newman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Telomerase regulates MYC-driven oncogenesis independent of its reverse transcriptase activity

(2015) Cheryl M. Koh et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioma cell invasion through induction of NF-κB-inducing kinase (NIK) and noncanonical NF-κB signaling

(2015) Evan M Cherry et al.   Molecular Cancer

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

(2015) R. J. A. Bell et al.   SCIENCE

Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology

(2014) Louis Tong et al.   BIOSCIENCE REPORTS

TACO: a general-purpose tool for predicting cell-type-specific transcription factor dimers

(2014) Aleksander Jankowski et al.   BMC GENOMICS

Noncanonical Functions of Telomerase: Implications in Telomerase-Targeted Cancer Therapies

(2014) Yinghui Li et al.   CANCER RESEARCH

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

(2014) Eun Myoung Shin et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic Cells Require the NF- B2 Pathway for Cross-Presentation of Soluble Antigens

(2014) E. F. Lind et al.   JOURNAL OF IMMUNOLOGY

Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade

(2014) Sandra Sampl et al.   Translational Oncology

Telomerase reverse transcriptase promoter mutations in primary cutaneous melanoma

(2014) Barbara Heidenreich et al.   Nature Communications

The NF-κB Genomic Landscape in Lymphoblastoid B Cells

(2014) Bo Zhao et al.   Cell Reports

A NIK-IKKα Module Expands ErbB2-Induced Tumor-Initiating Cells by Stimulating Nuclear Export of p27/Kip1

(2013) Weizhou Zhang et al.   CANCER CELL

ETS Transcription Factor ESE1/ELF3 Orchestrates a Positive Feedback Loop That Constitutively Activates NF- B and Drives Prostate Cancer Progression

(2013) N. Longoni et al.   CANCER RESEARCH

The Role of Telomeres in Stem Cells and Cancer

(2013) Cagatay Günes et al.   CELL

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Molecular mechanisms of ETS transcription factor-mediated tumorigenesis

(2013) Adwitiya Kar et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Fibroblast Growth Factor Inducible (Fn14)-specific Antibodies Concomitantly Display Signaling Pathway-specific Agonistic and Antagonistic Activity

(2013) Steffen Salzmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uniform, optimal signal processing of mapped deep-sequencing data

(2013) Vibhor Kumar et al.   NATURE BIOTECHNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

TherMos: Estimating protein–DNA binding energies from in vivo binding profiles

(2013) Wenjie Sun et al.   NUCLEIC ACIDS RESEARCH

The NF-κB RelB Protein Is an Oncogenic Driver of Mesenchymal Glioma

(2013) Dong Whan Lee et al.   PLoS One

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

Highly Recurrent TERT Promoter Mutations in Human Melanoma

(2013) F. W. Huang et al.   SCIENCE

Telomerase: central regulator of all of the hallmarks of cancer

(2013) Kee Chung Low et al.   TRENDS IN BIOCHEMICAL SCIENCES

Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA

(2013) Daisuke Mashiko et al.   Scientific Reports

Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer

(2012) Albert S. Baldwin   IMMUNOLOGICAL REVIEWS

EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis

(2012) Weiwei Yang et al.   MOLECULAR CELL

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Telomerase directly regulates NF-κB-dependent transcription

(2012) Arkasubhra Ghosh et al.   NATURE CELL BIOLOGY

Wnt Regulates TERT--Putting the Horse Before the Cart

(2012) C. W. Greider   SCIENCE

Wnt/ -Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells

(2012) K. Hoffmeyer et al.   SCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

(2011) Bahram Razani et al.   IMMUNOLOGICAL REVIEWS

NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses

(2011) Janin Hofmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

(2011) Trevor Siggers et al.   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

NF-κB inducing kinase (NIK) modulates melanoma tumorigenesis by regulating expression of pro-survival factors through the β-catenin pathway

(2011) Y M Thu et al.   ONCOGENE

Hexamethylene Bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF-κB activity: Implications for cancer therapy

(2010) Anwesha Dey et al.   CELL CYCLE

Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA

(2010) Nigar D. Babayeva et al.   CELL CYCLE

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

Soluble and Transmembrane TNF-Like Weak Inducer of Apoptosis Differentially Activate the Classical and Noncanonical NF- B Pathway

(2010) C. Roos et al.   JOURNAL OF IMMUNOLOGY

Integrative model of genomic factors for determining binding site selection by estrogen receptor-α

(2010) Roy Joseph et al.   Molecular Systems Biology

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Stabilization of RelB Requires Multidomain Interactions with p100/p52

(2008) Amanda J. Fusco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY