Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology

Phosphorylation-mediated regulation of GEFs for RhoA

(2014) Maulik Patel et al.   Cell Adhesion & Migration

The Non-Canonical IκB Kinases IKKε and TBK1 as Potential Targets for the Development of Novel Therapeutic Drugs

(2013) E. Niederberger et al.   CURRENT MOLECULAR MEDICINE

Telomerase: central regulator of all of the hallmarks of cancer

(2013) Kee Chung Low et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chronic adipose tissue inflammation: all immune cells on the stage

(2013) Gökhan Cildir et al.   TRENDS IN MOLECULAR MEDICINE

Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo

(2012) P. Rajendran et al.   Cancer Prevention Research

Rho GTPase function in development: How in vivo models change our view

(2012) Esben Pedersen et al.   EXPERIMENTAL CELL RESEARCH

Integrin signalling and function in immune cells

(2012) Yanbo Zhang et al.   IMMUNOLOGY

Conformational epitopes at cadherin calcium-binding sites and p120-catenin phosphorylation regulate cell adhesion

(2012) Yuliya I. Petrova et al.   MOLECULAR BIOLOGY OF THE CELL

Telomerase directly regulates NF-κB-dependent transcription

(2012) Arkasubhra Ghosh et al.   NATURE CELL BIOLOGY

The Hematopoietic Cell-Specific Rho GTPase Inhibitor ARHGDIB/D4GDI Limits HIV Type 1 Replication

(2011) Tadashi Watanabe et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Pharmacogenetics of genes across the doxorubicin pathway

(2011) David Jamieson et al.   Expert Opinion on Drug Metabolism & Toxicology

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

(2011) Bahram Razani et al.   IMMUNOLOGICAL REVIEWS

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Thrombin Induces NF-κB Activation and IL-8/CXCL8 Expression in Lung Epithelial Cells by a Rac1-dependent PI3K/Akt Pathway

(2011) Chien-Huang Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interferon-γ-induced GTPase, mGBP-2, Inhibits Tumor Necrosis Factor α (TNF-α) Induction of Matrix Metalloproteinase-9 (MMP-9) by Inhibiting NF-κB and Rac Protein

(2011) Sujata Balasubramanian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Epidermal Growth Factor Receptor Mediates Tumor Necrosis Factor-α-induced Activation of the ERK/GEF-H1/RhoA Pathway in Tubular Epithelium

(2011) Eli Kakiashvili et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction

(2011) Jing Peng et al.   Journal of Neuroinflammation

An ABC of the RHO subfamily

(2011) Katrin Legg   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The 'invisible hand': regulation of RHO GTPases by RHOGDIs

(2011) Rafael Garcia-Mata et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

Direct modifications of Rho proteins: deconstructing GTPase regulation

(2010) Orane Visvikis et al.   BIOLOGY OF THE CELL

Hexamethylene Bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF-κB activity: Implications for cancer therapy

(2010) Anwesha Dey et al.   CELL CYCLE

A single NFκB system for both canonical and non-canonical signaling

(2010) Vincent Feng-Sheng Shih et al.   CELL RESEARCH

The role of ubiquitylation and degradation in RhoGTPase signalling

(2010) Micha Nethe et al.   JOURNAL OF CELL SCIENCE

p53 and NFκB: fresh breath in the cross talk

(2009) Vinay Tergaonkar   CELL RESEARCH

Roles of NF-κB in health and disease: mechanisms and therapeutic potential

(2009) Ee Tsin Wong et al.   CLINICAL SCIENCE

Comprehending the complex connection between PKCβ, TAK1, and IKK in BCR signaling

(2009) Hisaaki Shinohara et al.   IMMUNOLOGICAL REVIEWS

Lipid Rafts and Caveolin-1 Coordinate Interleukin-1β (IL-1β)-dependent Activation of NFκB by Controlling Endocytosis of Nox2 and IL-1β Receptor 1 from the Plasma Membrane

(2009) Fredrick D. Oakley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac1 Signaling Modulates BCL-6-Mediated Repression of Gene Transcription

(2009) P. Barros et al.   MOLECULAR AND CELLULAR BIOLOGY

Rac1 regulates peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway

(2009) Bing-Chang Chen et al.   MOLECULAR IMMUNOLOGY

Potential pharmacological control of the NF-κB pathway

(2009) Gautam Sethi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Critical involvement of Rho GTPase activity in the efficient transplantation of neural stem cells into the injured spinal cord

(2009) Fujiki Numano et al.   Molecular Brain

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

(2008) L. Verstrepen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Integrin-dependent phagocytosis - spreading from microadhesion to new concepts

(2008) A. G. Dupuy et al.   JOURNAL OF CELL SCIENCE

Rac mediates TNF-induced cytokine production via modulation of NF-κB

(2008) Lynn M. Williams et al.   MOLECULAR IMMUNOLOGY

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY