Cyclic di-AMP mediates biofilm formation

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

(2015) TuAnh Ngoc Huynh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DhhP, a Cyclic di-AMP Phosphodiesterase of Borrelia burgdorferi, Is Essential for Cell Growth and Virulence

(2014) Meiping Ye et al.   INFECTION AND IMMUNITY

Functional analysis of c-di-AMP phosphodiesterase, GdpP, in Streptococcus suis serotype 2

(2014) Bin Du et al.   MICROBIOLOGICAL RESEARCH

Deletion of the cyclic di-AMP phosphodiesterase gene (cnpB) inMycobacterium tuberculosisleads to reduced virulence in a mouse model of infection

(2014) Jun Yang et al.   MOLECULAR MICROBIOLOGY

The Mucosal Adjuvant Cyclic di-AMP Exerts Immune Stimulatory Effects on Dendritic Cells and Macrophages

(2014) Ivana Škrnjug et al.   PLoS One

Highly Active Modulators of Indole Signaling Alter Pathogenic Behaviors in Gram-Negative and Gram-Positive Bacteria

(2013) Marine J. Minvielle et al.   CHEMISTRY-A EUROPEAN JOURNAL

Core-Gene-Encoded Peptide Regulating Virulence-Associated Traits in Streptococcus mutans

(2013) J. N. Kim et al.   JOURNAL OF BACTERIOLOGY

Two DHH Subfamily 1 Proteins in Streptococcus pneumoniae Possess Cyclic Di-AMP Phosphodiesterase Activity and Affect Bacterial Growth and Virulence

(2013) Y. Bai et al.   JOURNAL OF BACTERIOLOGY

Cyclic Di-AMP Impairs Potassium Uptake Mediated by a Cyclic Di-AMP Binding Protein in Streptococcus pneumoniae

(2013) Y. Bai et al.   JOURNAL OF BACTERIOLOGY

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cyclic di-AMP: another second messenger enters the fray

(2013) Rebecca M. Corrigan et al.   NATURE REVIEWS MICROBIOLOGY

MstX and a Putative Potassium Channel Facilitate Biofilm Formation in Bacillus subtilis

(2013) Matthew E. Lundberg et al.   PLoS One

Mutation in the C-Di-AMP Cyclase dacA Affects Fitness and Resistance of Methicillin Resistant Staphylococcus aureus

(2013) Vanina Dengler et al.   PLoS One

Systematic identification of conserved bacterial c-di-AMP receptor proteins

(2013) R. M. Corrigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during Chlamydia trachomatis Infection

(2013) J. R. Barker et al.   mBio

Identification of essential genes of the periodontal pathogen Porphyromonas gingivalis

(2012) Brian A Klein et al.   BMC GENOMICS

Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis

(2012) Dimpy Kalia et al.   CHEMICAL SOCIETY REVIEWS

Listeria monocytogenes Strain-Specific Impairment of the TetR Regulator Underlies the Drastic Increase in Cyclic di-AMP Secretion and Beta Interferon-Inducing Ability

(2012) Takeshi Yamamoto et al.   INFECTION AND IMMUNITY

Regulation of Bacteriocin Production and Cell Death by the VicRK Signaling System in Streptococcus mutans

(2012) D. B. Senadheera et al.   JOURNAL OF BACTERIOLOGY

Cyclic Di-AMP Homeostasis inBacillus subtilis

(2012) Felix M. P. Mehne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DarR, a TetR-like Transcriptional Factor, Is a Cyclic Di-AMP-responsive Repressor inMycobacterium smegmatis

(2012) Lei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A  D-dependent antisense transcript modulates expression of the cyclic-di-AMP hydrolase GdpP in Bacillus subtilis

(2012) Y. Luo et al.   MICROBIOLOGY-SGM

Mycobacterium tuberculosis Rv3586 (DacA) Is a Diadenylate Cyclase That Converts ATP or ADP into c-di-AMP

(2012) Yinlan Bai et al.   PLoS One

The Exopolysaccharide Matrix Modulates the Interaction between 3D Architecture and Virulence of a Mixed-Species Oral Biofilm

(2012) Jin Xiao et al.   PLoS Pathogens

A New Small Molecule Specifically Inhibits the Cariogenic Bacterium Streptococcus mutans in Multispecies Biofilms

(2011) Chang Liu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cloning-Independent and Counterselectable Markerless Mutagenesis System in Streptococcus mutans

(2011) Zhoujie Xie et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis

(2011) Yaara Oppenheimer-Shaanan et al.   EMBO REPORTS

A Molecular Chaperone Mediates a Two-protein Enzyme Complex and Glycosylation of Serine-rich Streptococcal Adhesins

(2011) Ren Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gene Regulation in S. mutans

(2011) E.G. Smith et al.   JOURNAL OF DENTAL RESEARCH

Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions

(2011) K. G. Roelofs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila melanogaster as an Animal Model for the Study of Pseudomonas aeruginosa Biofilm Infections In Vivo

(2011) Heidi Mulcahy et al.   PLoS Pathogens

c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress

(2011) Rebecca M. Corrigan et al.   PLoS Pathogens

Exopolysaccharides Produced by Streptococcus mutans Glucosyltransferases Modulate the Establishment of Microcolonies within Multispecies Biofilms

(2010) H. Koo et al.   JOURNAL OF BACTERIOLOGY

Quorum sensing in bacterial virulence

(2010) L. C. M. Antunes et al.   MICROBIOLOGY-SGM

cAMP, c-di-GMP, c-di-AMP and now cGMP: bacteria use them all!

(2010) Mark Gomelsky   MOLECULAR MICROBIOLOGY

Dynamics of Streptococcus mutans Transcriptome in Response to Starch and Sucrose during Biofilm Development

(2010) Marlise I. Klein et al.   PLoS One

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

(2010) J. J. Woodward et al.   SCIENCE

Extracellular Polysaccharides Matrix — An Often Forgotten Virulence Factor in Oral Biofilm Research

(2010) Hyun Koo et al.   International Journal of Oral Science

Quantifying Western blots: Pitfalls of densitometry

(2009) Max Gassmann et al.   ELECTROPHORESIS

YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity

(2009) Feng Rao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Principles of c-di-GMP signalling in bacteria

(2009) Regine Hengge   NATURE REVIEWS MICROBIOLOGY

The utility of affinity-tags for detection of a streptococcal protein from a variety of streptococcal species

(2008) Meixian Zhou et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Structural Biochemistry of a Bacterial Checkpoint Protein Reveals Diadenylate Cyclase Activity Regulated by DNA Recombination Intermediates

(2008) Gregor Witte et al.   MOLECULAR CELL

Accurate step wedge calibration for densitometry of electrophoresis gels

(2008) Han Yen Tan et al.   OPTICS COMMUNICATIONS

Great Times for Small Molecules: c-di-AMP, a Second Messenger Candidate in Bacteria and Archaea

(2008) U. Romling   Science Signaling