Oral supplementations with l-glutamine or l-alanyl-l-glutamine do not change metabolic alterations induced by long-term high-fat diet in the B6.129F2/J mouse model of insulin resistance

The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes

(2015) Mauricio Krause et al.   CLINICAL SCIENCE

Heat shock proteins and heat therapy for type 2 diabetes

(2015) Mauricio Krause et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

L-glutamine Supplementations Enhance Liver Glutamine-Glutathione Axis and Heat Shock Factor-1 Expression in Endurance-Exercise Trained Rats

(2015) Éder Ricardo Petry et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Chia (Salvia hispanica L.) enhances HSP, PGC-1α expressions and improves glucose tolerance in diet-induced obese rats

(2015) Rafaela da Silva Marineli et al.   NUTRITION

Characterization and Regulation of the Amino Acid Transporter SNAT2 in the Small Intestine of Piglets

(2015) Guangran Li et al.   PLoS One

Disturbed intestinal nitrogen homeostasis in a mouse model of high-fat diet-induced obesity and glucose intolerance

(2014) Thi Thu Huong Do et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Comparison of the long-term effects of high-fat v. low-fat diet consumption on cardiometabolic risk factors in subjects with abnormal glucose metabolism: a systematic review and meta-analysis

(2014) Lukas Schwingshackl et al.   BRITISH JOURNAL OF NUTRITION

Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice

(2014) Jing Liu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

The fat cell senescence hypothesis

(2014) Philip Newsholme et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Activating HSP72 in Rodent Skeletal Muscle Increases Mitochondrial Number and Oxidative Capacity and Decreases Insulin Resistance

(2014) Darren C. Henstridge et al.   DIABETES

Alanyl-glutamine improves pancreatic β-cell function following ex vivo inflammatory challenge

(2014) Vinicius Fernandes Cruzat et al.   JOURNAL OF ENDOCRINOLOGY

The Impact of High-Fat Diet on Metabolism and Immune Defense in Small Intestine Mucosa

(2014) Jacek R. Wiśniewski et al.   JOURNAL OF PROTEOME RESEARCH

Obesity depresses the anti-inflammatory HSP70 pathway, contributing to NAFLD progression

(2014) Fábio Cangeri Di Naso et al.   Obesity

Both Dietary Supplementation with Monosodium L-Glutamate and Fat Modify Circulating and Tissue Amino Acid Pools in Growing Pigs, but with Little Interactive Effect

(2014) Zemeng Feng et al.   PLoS One

Chaperoning to the metabolic party: The emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes

(2014) Darren C. Henstridge et al.   Molecular Metabolism

Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistancein vivoand cause pancreatic β-cell dysfunction and deathin vitro

(2013) Mauricio Krause et al.   CLINICAL SCIENCE

Augmented hepatic Toll-like receptors by fatty acids trigger the pro-inflammatory state of non-alcoholic fatty liver disease in mice

(2013) Koji Sawada et al.   HEPATOLOGY RESEARCH

Innate sensors of pathogen and stress: Linking inflammation to obesity

(2013) Chengcheng Jin et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Metabolic Signature Shift in Type 2 Diabetes Mellitus Revealed by Mass Spectrometry-based Metabolomics

(2013) Fengguo Xu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effects of a Lactobacillus paracasei B21060 based synbiotic on steatosis, insulin signaling and toll-like receptor expression in rats fed a high-fat diet

(2013) Giuseppina Mattace Raso et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Oral supplementations with free and dipeptide forms of l-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins

(2013) Vinicius F. Cruzat et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: Involvement of heat shock protein pathways

(2013) Éder Ricardo Petry et al.   LIFE SCIENCES

Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia

(2013) Vinicius Fernandes Cruzat et al.   NUTRITION

High-fat diet action on adiposity, inflammation, and insulin sensitivity depends on the control low-fat diet

(2013) Bérengère Benoit et al.   NUTRITION RESEARCH

Isocaloric intake of a high-fat diet promotes insulin resistance and inflammation in Wistar rats

(2012) Patrícia Silva Jacob et al.   CELL BIOCHEMISTRY AND FUNCTION

Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?

(2012) Josianne Rodrigues-Krause et al.   CELL STRESS & CHAPERONES

Aging Does Not Reduce Heat Shock Protein 70 in the Absence of Chronic Insulin Resistance

(2012) K. Kavanagh et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Catabolism of amino acids in livers from cafeteria-fed rats

(2012) Cristiane Vizioli de Castro Ghizoni et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Restoring HSP70 deficiencies improves glucose tolerance in diabetic monkeys

(2011) Kylie Kavanagh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans

(2011) Olivier Bezy et al.   JOURNAL OF CLINICAL INVESTIGATION

Amino acids and diabetes: implications for endocrine, metabolic and immune function

(2010) Philip Newsholme   Frontiers in Bioscience-Landmark

Free fatty acids induce endothelial dysfunction and activate protein kinase C and nuclear factor-κB pathway in rat aorta

(2010) Hua Li et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The relationship between heat shock protein 72 expression in skeletal muscle and insulin sensitivity is dependent on adiposity

(2010) Darren C. Henstridge et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The death effector domain-containing DEDD forms a complex with Akt and Hsp90, and supports their stability

(2009) Nobuya Kurabe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Selective amino acid deficiency in patients with impaired glucose tolerance and type 2 diabetes

(2009) Bjoern A. Menge et al.   REGULATORY PEPTIDES

Atherosclerosis: A redox-sensitive lipid imbalance suppressible by cyclopentenone prostaglandins

(2008) Lucila Ludmila Paula Gutierrez et al.   BIOCHEMICAL PHARMACOLOGY

Dietary l-Arginine Supplementation Reduces White Fat Gain and Enhances Skeletal Muscle and Brown Fat Masses in Diet-Induced Obese Rats

(2008) Wenjuan Jobgen et al.   JOURNAL OF NUTRITION