Alanyl-glutamine improves pancreatic β-cell function following ex vivo inflammatory challenge

Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics

(2014) Wendy S. Hahn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Acute nutrient regulation of the mitochondrial glutathione redox state in pancreatic β-cells

(2014) Hilton K. Takahashi et al.   BIOCHEMICAL JOURNAL

The fat cell senescence hypothesis

(2014) Philip Newsholme et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6

(2014) Dominika Nackiewicz et al.   DIABETOLOGIA

Nutrient regulation of insulin secretion and action

(2014) Philip Newsholme et al.   JOURNAL OF ENDOCRINOLOGY

Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistancein vivoand cause pancreatic β-cell dysfunction and deathin vitro

(2013) Mauricio Krause et al.   CLINICAL SCIENCE

The loss of Sirt1 in mouse pancreatic beta cells impairs insulin secretion by disrupting glucose sensing

(2013) L. Luu et al.   DIABETOLOGIA

Oral supplementations with free and dipeptide forms of l-glutamine in endotoxemic mice: effects on muscle glutamine-glutathione axis and heat shock proteins

(2013) Vinicius F. Cruzat et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Alanyl-glutamine and glutamine plus alanine supplements improve skeletal redox status in trained rats: Involvement of heat shock protein pathways

(2013) Éder Ricardo Petry et al.   LIFE SCIENCES

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia

(2013) Vinicius Fernandes Cruzat et al.   NUTRITION

Sirtuin-1 is a nutrient-dependent modulator of inflammation

(2013) Maya E. Kotas et al.   Adipocyte

Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes

(2012) I. Marhfour et al.   DIABETOLOGIA

IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030

(2011) David R. Whiting et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

l-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

(2011) Mauricio S Krause et al.   JOURNAL OF ENDOCRINOLOGY

Effects of dietary glutamine on inflammatory mediator gene expressions in rats with streptozotocin-induced diabetes

(2011) Pei-Hsuan Tsai et al.   NUTRITION

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

(2010) E. Akude et al.   DIABETES

Hexosamines stimulate apoptosis by altering SIRT1 action and levels in rodent pancreatic  -cells

(2010) M. Lafontaine-Lacasse et al.   JOURNAL OF ENDOCRINOLOGY

Effects of supplementation with free glutamine and the dipeptide alanyl-glutamine on parameters of muscle damage and inflammation in rats submitted to prolonged exercise

(2009) Vinicius Fernandes Cruzat et al.   CELL BIOCHEMISTRY AND FUNCTION

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

(2009) P. Newsholme et al.   DIABETOLOGIA

Islet-associated macrophages in type 2 diabetes

(2009) S. J. Richardson et al.   DIABETOLOGIA

Selective amino acid deficiency in patients with impaired glucose tolerance and type 2 diabetes

(2009) Bjoern A. Menge et al.   REGULATORY PEPTIDES

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

(2008) Inki Kim et al.   NATURE REVIEWS DRUG DISCOVERY

Effects of oral supplementation with glutamine and alanyl-glutamine on glutamine, glutamate, and glutathione status in trained rats and subjected to long-duration exercise

(2008) Vinicius Fernandes Cruzat et al.   NUTRITION

Obesity, Metabolic Syndrome, and Type 2 Diabetes: Inflammatory Basis of Glucose Metabolic Disorders

(2008) Aruna Pradhan   NUTRITION REVIEWS

HSP72 protects against obesity-induced insulin resistance

(2008) J. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA