Apoptotic Death of Cancer Stem Cells for Cancer Therapy

Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells

(2016) Jia Guo et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells

(2013) Shaobin Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes

(2013) Xu Ma et al.   BIOMATERIALS

MicroRNA aberrances in head and neck cancer

(2013) Hsi-Feng Tu et al.   Current Opinion in Otolaryngology & Head and Neck Surgery

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma

(2013) TADASHI ASHIZAWA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Repression of mammary adipogenesis by genistein limits mammosphere formation of human MCF-7 cells

(2013) Maria Theresa E Montales et al.   JOURNAL OF ENDOCRINOLOGY

Morusin inhibits human cervical cancer stem cell growth and migration through attenuation of NF-κB activity and apoptosis induction

(2013) Li Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Evidence for Two Modes of Synergistic Induction of Apoptosis by Mapatumumab and Oxaliplatin in Combination with Hyperthermia in Human Colon Cancer Cells

(2013) Xinxin Song et al.   PLoS One

IMD-0354 Targets Breast Cancer Stem Cells: A Novel Approach for an Adjuvant to Chemotherapy to Prevent Multidrug Resistance in a Murine Model

(2013) Azucena Gomez-Cabrero et al.   PLoS One

Topoisomerase I Inhibitors, Shikonin and Topotecan, Inhibit Growth and Induce Apoptosis of Glioma Cells and Glioma Stem Cells

(2013) Feng-Lei Zhang et al.   PLoS One

Preferential eradication of acute myelogenous leukemia stem cells by fenretinide

(2013) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterogeneity and immunophenotypic plasticity of malignant cells in human liposarcomas

(2013) Yan Zhang et al.   Stem Cell Research

Synergistic Effect of the γ-Secretase Inhibitor PF-03084014 and Docetaxel in Breast Cancer Models

(2013) Cathy C. Zhang et al.   Stem Cells Translational Medicine

NVP-LDE-225 (Erismodegib) inhibits epithelial–mesenchymal transition and human prostate cancer stem cell growth in NOD/SCID IL2Rγ null mice by regulating Bmi-1 and microRNA-128

(2013) R Nanta et al.   Oncogenesis

Survivin is highly expressed in CD34+38- leukemic stem/progenitor cells and predicts poor clinical outcomes in AML

(2012) B. Z. Carter et al.   BLOOD

Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells

(2012) Maria Theresa E. Montales et al.   CARCINOGENESIS

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

miRNAs expressed differently in cancer stem cells and cancer cells of human gastric cancer cell line MKN-45

(2012) Azadeh Fahim Golestaneh et al.   CELL BIOCHEMISTRY AND FUNCTION

Targeting CSC-Related miRNAs for Cancer Therapy by Natural Agents

(2012) Bin Bao et al.   CURRENT DRUG TARGETS

The selective cytotoxic activity in breast cancer cells by an anthranilic alcohol-derived acyclic 5-fluorouracil O,N-acetal is mediated by endoplasmic reticulum stress-induced apoptosis

(2012) Octavio Caba et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Transforming Growth Factor β1 Signal is Crucial for Dedifferentiation of Cancer Cells to Cancer Stem Cells in Osteosarcoma

(2012) Haixia Zhang et al.   STEM CELLS

Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity

(2012) S Akunuru et al.   Cell Death & Disease

Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI

(2011) Yi-Ping Yang et al.   BIOMATERIALS

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

(2011) Nicolas Goardon et al.   CANCER CELL

Cisplatin Restores TRAIL Apoptotic Pathway in Glioblastoma-Derived Stem Cells through Up-regulation of DR5 and Down-regulation of c-FLIP

(2011) Lijuan Ding et al.   CANCER INVESTIGATION

Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells

(2011) Guan-Nan Zhang et al.   CANCER LETTERS

Targeting apoptosis pathways in cancer stem cells

(2011) Michele Signore et al.   CANCER LETTERS

CD24 enhances DNA damage-induced apoptosis by modulating NF-κB signaling in CD44-expressing breast cancer cells

(2011) Ji-hyun Ju et al.   CARCINOGENESIS

Distinct Types of Tumor-Initiating Cells Form Human Colon Cancer Tumors and Metastases

(2011) Sebastian M. Dieter et al.   Cell Stem Cell

Reduced miR-128 in Breast Tumor-Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5

(2011) Y. Zhu et al.   CLINICAL CANCER RESEARCH

Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine

(2011) Octavio Caba et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Overexpression of ZNF217 in glioblastoma contributes to the maintenance of glioma stem cells regulated by hypoxia-inducible factors

(2011) Xing-gang Mao et al.   LABORATORY INVESTIGATION

Targeting the Mitochondria Activates Two Independent Cell Death Pathways in Ovarian Cancer Stem Cells

(2011) A. B. Alvero et al.   MOLECULAR CANCER THERAPEUTICS

Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-  and integrin/focal adhesion kinase (FAK) signaling

(2011) M. Schober et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric cancer cell division regulated by AKT

(2011) I. Dey-Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells

(2011) J. M. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase

(2010) Puspa R. Pandey et al.   BREAST CANCER RESEARCH AND TREATMENT

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

CD44posCD49fhiCD133/2hi Defines Xenograft-Initiating Cells in Estrogen Receptor–Negative Breast Cancer

(2010) Matthew J. Meyer et al.   CANCER RESEARCH

Therapeutic Antibody Targeting of CD47 Eliminates Human Acute Lymphoblastic Leukemia

(2010) Mark P. Chao et al.   CANCER RESEARCH

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

(2010) Fadila Guessous et al.   CELL CYCLE

miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

(2010) Stephanie Ma et al.   Cell Stem Cell

The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth

(2010) C. O. Marian et al.   CLINICAL CANCER RESEARCH

MiR-222 Overexpression Confers Cell Migratory Advantages in Hepatocellular Carcinoma through Enhancing AKT Signaling

(2010) Q. W-L. Wong et al.   CLINICAL CANCER RESEARCH

Targeting Notch to Target Cancer Stem Cells

(2010) A. Pannuti et al.   CLINICAL CANCER RESEARCH

The therapeutic promise of the cancer stem cell concept

(2010) Natasha Y. Frank et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic variegation of clonal architecture and propagating cells in leukaemia

(2010) Kristina Anderson et al.   NATURE

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

miR-21as a key regulator of oncogenic processes

(2009) S. Duygu Selcuklu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Cancer cells with high expression of CD133 exert FLIP upregulation and resistance to TRAIL-induced apoptosis

(2009) Marina Stantic et al.   BIOFACTORS

Targeting breast stem cells with the cancer preventive compounds curcumin and piperine

(2009) Madhuri Kakarala et al.   BREAST CANCER RESEARCH AND TREATMENT

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Side population in oral squamous cell carcinoma possesses tumor stem cell phenotypes

(2009) Ping Zhang et al.   CANCER LETTERS

MicroRNAs: Novel regulators in the hallmarks of human cancer

(2009) Kai Ruan et al.   CANCER LETTERS

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

(2009) H. A. Hirsch et al.   CANCER RESEARCH

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Nanoparticle-mediated combination chemotherapy and photodynamic therapy overcomes tumor drug resistance

(2009) Ayman Khdair et al.   JOURNAL OF CONTROLLED RELEASE

Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

(2009) C Coulouarn et al.   ONCOGENE

MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

(2009) Qing Ji et al.   PLoS One

miR-221 overexpression contributes to liver tumorigenesis

(2009) P. Pineau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP

(2008) Renata Zobalova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Synergistic Proapoptotic Activity of Recombinant TRAIL Plus the Akt Inhibitor Perifosine in Acute Myelogenous Leukemia Cells

(2008) P. L. Tazzari et al.   CANCER RESEARCH

Targeting the extrinsic apoptosis pathway in cancer

(2008) Avi Ashkenazi   CYTOKINE & GROWTH FACTOR REVIEWS

MicroRNA-223 Is Commonly Repressed in Hepatocellular Carcinoma and Potentiates Expression of Stathmin1

(2008) Queenie W.–L. Wong et al.   GASTROENTEROLOGY

A potential target associated with both cancer and cancer stem cells: A combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes

(2008) Yang Liu et al.   JOURNAL OF CONTROLLED RELEASE

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

The genetics of the p53 pathway, apoptosis and cancer therapy

(2008) Alexei Vazquez et al.   NATURE REVIEWS DRUG DISCOVERY

Directing cancer cells to self-destruct with pro-apoptotic receptor agonists

(2008) Avi Ashkenazi   NATURE REVIEWS DRUG DISCOVERY

Comparison between cells and cancer stem-like cells isolated from glioblastoma and astrocytoma on expression of anti-apoptotic and multidrug resistance–associated protein genes

(2008) F. Jin et al.   NEUROSCIENCE

IAP-targeted therapies for cancer

(2008) E C LaCasse et al.   ONCOGENE

Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

(2008) K E Tagscherer et al.   ONCOGENE

Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions

(2008) Richard Birnie et al.   GENOME BIOLOGY

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY