Transforming Growth Factor β1 Signal is Crucial for Dedifferentiation of Cancer Cells to Cancer Stem Cells in Osteosarcoma

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition

(2011) Logan A Walsh et al.   Cell Communication and Signaling

Blocking HIF1α Activity Eliminates Hematological Cancer Stem Cells

(2011) Ben S. Lam et al.   Cell Stem Cell

Human primary bone sarcomas contain CD133+ cancer stem cells displaying high tumorigenicity in vivo

(2011) Virginia Tirino et al.   FASEB JOURNAL

Noncanonical TGF-β Signaling During Mammary Tumorigenesis

(2011) Jenny G. Parvani et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Enrichment of osteosarcoma stem cells by chemotherapy

(2011) Qing-Lian Tang et al.   Chinese Journal of Cancer

A Central Role for Hypoxic Signaling in Cartilage, Bone, and Hematopoiesis

(2011) Erinn B. Rankin et al.   Current Osteoporosis Reports

CD117 and Stro-1 Identify Osteosarcoma Tumor-Initiating Cells Associated with Metastasis and Drug Resistance

(2010) Amit S. Adhikari et al.   CANCER RESEARCH

Transcriptional crosstalk between TGFβ and stem cell pathways in tumor cell invasion: Role of EMT promoting Smad complexes

(2010) Jonas Fuxe et al.   CELL CYCLE

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

Induction of invasion in an organotypic oral cancer model by CoCl2, a hypoxia mimetic

(2010) Ingvild J. Brusevold et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

The Pathophysiology of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor-β in Normal and Malignant Mammary Epithelial Cells

(2010) Molly A. Taylor et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Vasculogenic mimicry–potential target for glioblastoma therapy: an in vitro and in vivo study

(2010) Yinsheng Chen et al.   MEDICAL ONCOLOGY

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

Notch1 regulates the functional contribution of RhoC to cervical carcinoma progression

(2009) S Srivastava et al.   BRITISH JOURNAL OF CANCER

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion

(2009) J Chen et al.   BRITISH JOURNAL OF CANCER

Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells Mediate Metastasis and Poor Clinical Outcome in Inflammatory Breast Cancer

(2009) E. Charafe-Jauffret et al.   CLINICAL CANCER RESEARCH

The TGF-β paradox in human cancer: an update

(2009) Maozhen Tian et al.   Future Oncology

International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons

(2009) Lisa Mirabello et al.   INTERNATIONAL JOURNAL OF CANCER

Hypoxia-inducible factors in stem cells and cancer

(2009) Jolly Mazumdar et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The hematopoietic stem cell niche: Low in oxygen but a nice place to be

(2009) Pernilla Eliasson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Radiation Resistance of Breast Cancer Stem Cells: Understanding the Clinical Framework

(2009) Bisrat G. Debeb et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss ofCdkn2

(2009) Alexander B Mohseny et al.   JOURNAL OF PATHOLOGY

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

TGFβ in Cancer

(2008) Joan Massagué   CELL

Hypoxia Markers in Human Osteosarcoma: An Exploratory Study

(2008) Hiroo Mizobuchi et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Wnt signaling controls the fate of mesenchymal stem cells

(2008) Ling Ling et al.   GENE

Epithelial injury induces an innate repair mechanism linked to cellular senescence and fibrosis involving IGF-binding protein-5

(2008) Gordon J Allan et al.   JOURNAL OF ENDOCRINOLOGY

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute

Expression and significance of hypoxemia-inducible factor-1α in osteosarcoma of the jaws

(2008) Wei-liang Chen et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Wnt signaling and skeletal development

(2007) Fei Liu et al.   CELLULAR SIGNALLING