Inflammation as a Keystone of Bone Marrow Stroma Alterations in Primary Myelofibrosis
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Title
Inflammation as a Keystone of Bone Marrow Stroma Alterations in Primary Myelofibrosis
Authors
Keywords
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Journal
MEDIATORS OF INFLAMMATION
Volume 2015, Issue -, Pages 1-16
Publisher
Hindawi Limited
Online
2015-11-13
DOI
10.1155/2015/415024
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Note: Only part of the references are listed.- TGF- signaling in the control of hematopoietic stem cells
- (2015) U. Blank et al. BLOOD
- Activation of non-canonical TGF-β1 signaling indicates an autoimmune mechanism for bone marrow fibrosis in primary myelofibrosis
- (2015) Fiorella Ciaffoni et al. BLOOD CELLS MOLECULES AND DISEASES
- Osteogenic Potential of Mesenchymal Stromal Cells Contributes to Primary Myelofibrosis
- (2015) C. Martinaud et al. CANCER RESEARCH
- Chronic Inflammation Induces a Novel Epigenetic Program That Is Conserved in Intestinal Adenomas and in Colorectal Cancer
- (2015) M. Abu-Remaileh et al. CANCER RESEARCH
- CD133 marks a stem cell population that drives human primary myelofibrosis
- (2015) I. Triviai et al. HAEMATOLOGICA
- PDGFB hypomethylation is a favourable prognostic biomarker in primary myelofibrosis
- (2015) Claudia Augello et al. LEUKEMIA RESEARCH
- Effect of Mutation Order on Myeloproliferative Neoplasms
- (2015) Christina A. Ortmann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tenascins in fibrotic disorders—from bench to bedside
- (2015) M Kasprzycka et al. Cell Adhesion & Migration
- CD133 marks a stem cell population that drives human primary myelofibrosis
- (2015) I. Triviai et al. HAEMATOLOGICA
- Sonic Hedgehog Produced by Bone Marrow-Derived Mesenchymal Stromal Cells Supports Cell Survival in Myelodysplastic Syndrome
- (2015) Jixue Zou et al. Stem Cells International
- Immune Derangements in Patients with Myelofibrosis: The Role of Treg, Th17, and sIL2Rα
- (2015) Jen C. Wang et al. PLoS One
- Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms
- (2014) P. Lundberg et al. BLOOD
- Epigenetic Targeting of Ovarian Cancer Stem Cells
- (2014) Yinu Wang et al. CANCER RESEARCH
- TGF-β1 Suppresses Plasmin and MMP Activity in Flexor Tendon Cells via PAI-1: Implications for Scarless Flexor Tendon Repair
- (2014) Youssef M. Farhat et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Targeting hedgehog signaling in myelofibrosis and other hematologic malignancies
- (2014) Raoul Tibes et al. Journal of Hematology & Oncology
- Age-Dependent Neonatal Intracerebral Hemorrhage in Plasminogen Activator Inhibitor 1 Knockout Mice
- (2014) Philippe Leroux et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons
- (2014) A Tefferi et al. LEUKEMIA
- Functional and genetic aberrations of in vitro-cultured marrow-derived mesenchymal stromal cells of patients with classical Philadelphia-negative myeloproliferative neoplasms
- (2014) M A Avanzini et al. LEUKEMIA
- Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms
- (2014) Lorena Arranz et al. NATURE
- The bone marrow niche for haematopoietic stem cells
- (2014) Sean J. Morrison et al. NATURE
- Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts
- (2014) Aruna Kode et al. NATURE
- Fibrosis—a lethal component of systemic sclerosis
- (2014) Yuen Yee Ho et al. Nature Reviews Rheumatology
- Transforming growth factor β—at the centre of systemic sclerosis
- (2014) Robert Lafyatis Nature Reviews Rheumatology
- Mpl Traffics to the Cell Surface Through Conventional and Unconventional Routes
- (2014) Cédric Cleyrat et al. TRAFFIC
- MicroRNAs linking inflamm-aging, cellular senescence and cancer
- (2013) Fabiola Olivieri et al. AGEING RESEARCH REVIEWS
- Primary myelofibrosis: 2013 update on diagnosis, risk-stratification, and management
- (2013) Ayalew Tefferi AMERICAN JOURNAL OF HEMATOLOGY
- Associations and prognostic interactions between circulating levels of hepcidin, ferritin and inflammatory cytokines in primary myelofibrosis
- (2013) Animesh Pardanani et al. AMERICAN JOURNAL OF HEMATOLOGY
- Ruxolitinib is a potent immunosuppressive compound: is it time for anti-infective prophylaxis?
- (2013) A. Heine et al. BLOOD
- The role of cytokines in the initiation and progression of myelofibrosis
- (2013) Hans C. Hasselbalch CYTOKINE & GROWTH FACTOR REVIEWS
- Array comparative genomic hybridization and sequencing of 23 genes in 80 patients with myelofibrosis at chronic or acute phase
- (2013) M. Brecqueville et al. HAEMATOLOGICA
- Resolution of bone marrow fibrosis in a patient receiving JAK1/JAK2 inhibitor treatment with ruxolitinib
- (2013) B. S. Wilkins et al. HAEMATOLOGICA
- HCV core-mediated activation of latent TGF-β via thrombospondin drives the crosstalk between hepatocytes and stromal environment
- (2013) Nassima Benzoubir et al. JOURNAL OF HEPATOLOGY
- Targeted cancer exome sequencing reveals recurrent mutations in myeloproliferative neoplasms
- (2013) E Tenedini et al. LEUKEMIA
- Rapid and long-lasting decrease of T-regulatory cells in patients with myelofibrosis treated with ruxolitinib
- (2013) M Massa et al. LEUKEMIA
- Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
- (2013) Lei Ding et al. NATURE
- Large conserved domains of low DNA methylation maintained by Dnmt3a
- (2013) Mira Jeong et al. NATURE GENETICS
- Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
- (2013) Neil C Henderson et al. NATURE MEDICINE
- Somatic CALR Mutations in Myeloproliferative Neoplasms with Nonmutated JAK2
- (2013) J. Nangalia et al. NEW ENGLAND JOURNAL OF MEDICINE
- Somatic Mutations of Calreticulin in Myeloproliferative Neoplasms
- (2013) Thorsten Klampfl et al. NEW ENGLAND JOURNAL OF MEDICINE
- Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities
- (2013) I. Tabas et al. SCIENCE
- Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β
- (2012) Robert Matthew Kottmann et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer?
- (2012) H. C. Hasselbalch BLOOD
- Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion
- (2012) C. Tripodo et al. BLOOD
- Alterations of polycomb gene BMI1 in human myeloproliferative neoplasms
- (2012) Mandy Brecqueville et al. CELL CYCLE
- Mutation analysis ofASXL1, CBL, DNMT3A, IDH1, IDH2, JAK2, MPL, NF1, SF3B1, SUZ12,andTET2in myeloproliferative neoplasms
- (2012) Mandy Brecqueville et al. GENES CHROMOSOMES & CANCER
- Chronic inflammation as a promotor of mutagenesis in essential thrombocythemia, polycythemia vera and myelofibrosis. A human inflammation model for cancer development?
- (2012) Hans Carl Hasselbalch LEUKEMIA RESEARCH
- One Thousand Patients With Primary Myelofibrosis: The Mayo Clinic Experience
- (2012) Ayalew Tefferi et al. MAYO CLINIC PROCEEDINGS
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inflammatory memories: Is epigenetics the missing link to persistent stromal cell activation in rheumatoid arthritis?
- (2011) Caroline Ospelt et al. AUTOIMMUNITY REVIEWS
- Recombinant interferon- may retard progression of early primary myelofibrosis: a preliminary report
- (2011) R. T. Silver et al. BLOOD
- Endothelial progenitor cells are clonal and exhibit the JAK2V617F mutation in a subset of thrombotic patients with Ph-negative myeloproliferative neoplasms
- (2011) L. Teofili et al. BLOOD
- Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands
- (2011) Heather M. O'Hagan et al. CANCER CELL
- Bone Marrow Stroma-Secreted Cytokines Protect JAK2V617F-Mutated Cells from the Effects of a JAK2 Inhibitor
- (2011) T. Manshouri et al. CANCER RESEARCH
- Identification of oncostatin M as a JAK2 V617F-dependent amplifier of cytokine production and bone marrow remodeling in myeloproliferative neoplasms
- (2011) Gregor Hoermann et al. FASEB JOURNAL
- Circulating Interleukin (IL)-8, IL-2R, IL-12, and IL-15 Levels Are Independently Prognostic in Primary Myelofibrosis: A Comprehensive Cytokine Profiling Study
- (2011) Ayalew Tefferi et al. JOURNAL OF CLINICAL ONCOLOGY
- Increased expression of vascular endothelial growth factor receptor 1 correlates with VEGF and microvessel density in Philadelphia chromosome-negative myeloproliferative neoplasms
- (2011) L. Boiocchi et al. JOURNAL OF CLINICAL PATHOLOGY
- Latent TGF-β structure and activation
- (2011) Minlong Shi et al. NATURE
- Progress and challenges in translating the biology of atherosclerosis
- (2011) Peter Libby et al. NATURE
- TGF-β Regulates DNA Methyltransferase Expression in Prostate Cancer, Correlates with Aggressive Capabilities, and Predicts Disease Recurrence
- (2011) Qiang Zhang et al. PLoS One
- Thrombospondin-1 (TSP-1) in primary myelofibrosis (PMF) — a megakaryocyte-derived biomarker which largely discriminates PMF from essential thrombocythemia
- (2010) Michaela Muth et al. ANNALS OF HEMATOLOGY
- Oncostatin M-enhanced vascular endothelial growth factor expression in human vascular smooth muscle cells involves PI3K-, p38 MAPK-, Erk1/2- and STAT1/STAT3-dependent pathways and is attenuated by interferon-γ
- (2010) Svitlana Demyanets et al. BASIC RESEARCH IN CARDIOLOGY
- Donor Cell Leukemia: A Review
- (2010) Daniel H. Wiseman BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Thrombospondin-1 is not the major activator of TGF- 1 in thrombopoietin-induced myelofibrosis
- (2010) S. Evrard et al. BLOOD
- Evaluation of the bioactive and total transforming growth factor β1 levels in primary myelofibrosis
- (2010) Rita Campanelli et al. CYTOKINE
- Epigenetic Histone Methylation Modulates Fibrotic Gene Expression
- (2010) G. Sun et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Cryopyrin-associated periodic syndromes: background and therapeutics
- (2010) Tetsuo Kubota et al. Modern Rheumatology
- Upregulation of DNA Methyltransferase-Mediated Gene Silencing, Anchorage-Independent Growth, and Migration of Colon Cancer Cells by Interleukin-6
- (2010) E. Foran et al. MOLECULAR CANCER RESEARCH
- Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
- (2010) Marc H. G. P. Raaijmakers et al. NATURE
- Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
- (2010) Simón Méndez-Ferrer et al. NATURE
- MicroRNA-target pairs in human renal epithelial cells treated with transforming growth factor β1: a novel role of miR-382
- (2010) Alison J. Kriegel et al. NUCLEIC ACIDS RESEARCH
- PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma
- (2010) Jennifer Freytag et al. Journal of Oncology
- Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation
- (2009) N. Kroger et al. BLOOD
- The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
- (2009) J. W. Vardiman et al. BLOOD
- High-resolution single-nucleotide polymorphism array-profiling in myeloproliferative neoplasms identifies novel genomic aberrations
- (2009) F. Stegelmann et al. HAEMATOLOGICA
- Epigenetic therapy in myeloproliferative neoplasms: evidence and perspectives
- (2009) Alessandro M. Vannucchi et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence
- (2008) J.-J. Lataillade et al. BLOOD
- New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment
- (2008) F. Cervantes et al. BLOOD
- Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
- (2008) Junping Wei et al. CANCER CELL
- Methylation of the suppressor of cytokine signaling 3 gene (SOCS3) in myeloproliferative disorders
- (2008) N. Fourouclas et al. HAEMATOLOGICA
- New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition
- (2008) R Chaligné et al. LEUKEMIA
- Interferon-α therapy in bcr-abl-negative myeloproliferative neoplasms
- (2008) J-J Kiladjian et al. LEUKEMIA
- Haematopoietic stem cell release is regulated by circadian oscillations
- (2008) Simón Méndez-Ferrer et al. NATURE
- Wound repair and regeneration
- (2008) Geoffrey C. Gurtner et al. NATURE
- Hypermethylation ofCXCR4Promoter in CD34+Cells from Patients with Primary Myelofibrosis
- (2008) Costanza Bogani et al. STEM CELLS
- Linking genes to literature: text mining, information extraction, and retrieval applications for biology
- (2008) Martin Krallinger et al. GENOME BIOLOGY
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