Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans

Osteopontin Modulates Inflammation, Mucin Production, and Gene Expression Signatures After Inhalation of Asbestos in a Murine Model of Fibrosis

(2011) Tara Sabo-Attwood et al.   AMERICAN JOURNAL OF PATHOLOGY

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells

(2011) Rodolphe Carpentier et al.   GASTROENTEROLOGY

Elevated Hedgehog/Gli signaling causes  -cell dedifferentiation in mice

(2011) L. Landsman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the role of SOX9 in acquired diseases: lessons from development

(2011) James Pritchett et al.   TRENDS IN MOLECULAR MEDICINE

Osteopontin Overproduction Is Associated with Progression of Glomerular Fibrosis in a Rat Model of Anti-Glomerular Basement Membrane Glomerulonephritis

(2010) Justin Merszei et al.   AMERICAN JOURNAL OF NEPHROLOGY

Matricellular proteins: from homeostasis to inflammation, cancer, and metastasis

(2010) Claudia Chiodoni et al.   CANCER AND METASTASIS REVIEWS

Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo

(2010) Jacqueline D. Peacock et al.   CIRCULATION RESEARCH

Plasma osteopontin concentration correlates with the severity of hepatic fibrosis and inflammation in HCV-infected subjects

(2010) Wenbao Huang et al.   CLINICA CHIMICA ACTA

Genetic Labeling Does Not Detect Epithelial-to-Mesenchymal Transition of Cholangiocytes in Liver Fibrosis in Mice

(2010) David Scholten et al.   GASTROENTEROLOGY

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme

(2010) Rannar Airik et al.   HUMAN MOLECULAR GENETICS

Hedgehog signaling in the liver

(2010) Alessia Omenetti et al.   JOURNAL OF HEPATOLOGY

Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

(2010) X. Wen et al.   MOLECULAR AND CELLULAR BIOLOGY

A Competitive Transcription Factor Binding Mechanism Determines the Timing of Late Cell Cycle-Dependent Gene Expression

(2010) Zoulfia Darieva et al.   MOLECULAR CELL

Osteopontin: A Biomarker to Predict the Outcome of Inflammatory Heart Disease

(2010) Karin Klingel et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

(2010) Monique T. Barakat et al.   TRENDS IN MOLECULAR MEDICINE

Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3

(2009) Manuela Wuelling et al.   DEVELOPMENTAL BIOLOGY

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

(2009) Aline Antoniou et al.   GASTROENTEROLOGY

The Hedgehog Pathway Transcription Factor GLI1 Promotes Malignant Behavior of Cancer Cells by Up-regulating Osteopontin

(2009) Shamik Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-range regulation at the SOX9 locus in development and disease

(2009) C T Gordon et al.   JOURNAL OF MEDICAL GENETICS

Scleraxis Is Required for Cell Lineage Differentiation and Extracellular Matrix Remodeling During Murine Heart Valve Formation In Vivo

(2008) Agata K. Levay et al.   CIRCULATION RESEARCH

Six2 functions redundantly immediately downstream of Hoxa2

(2008) E. Kutejova et al.   DEVELOPMENT

Role of osteopontin in cellular signaling and metastatic phenotype

(2008) Mohamed et al.   Frontiers in Bioscience-Landmark

Mechanisms of Hepatic Fibrogenesis

(2008) Scott L. Friedman   GASTROENTEROLOGY

Ectopic SOX9 Mediates Extracellular Matrix Deposition Characteristic of Organ Fibrosis

(2008) Karen Piper Hanley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

(2008) Ryoichi Mori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

(2007) Liu Yang et al.   JOURNAL OF HEPATOLOGY