Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

Plasma osteopontin concentration correlates with the severity of hepatic fibrosis and inflammation in HCV-infected subjects

(2010) Wenbao Huang et al.   CLINICA CHIMICA ACTA

Signals from dying hepatocytes trigger growth of liver progenitors

(2010) Y. Jung et al.   GUT

Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease

(2010) Wing-Kin Syn et al.   HEPATOLOGY

Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells

(2010) Steve S. Choi et al.   HEPATOLOGY

The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice

(2010) Peter Fickert et al.   LABORATORY INVESTIGATION

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

(2009) Steve S. Choi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Role of liver-infiltrating CD3+CD56+ natural killer T cells in the pathogenesis of nonalcoholic fatty liver disease

(2009) Kazuto Tajiri et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Role for hedgehog pathway in regulating growth and function of invariant NKT cells

(2009) Wing-Kin Syn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Hedgehog-Mediated Epithelial-to-Mesenchymal Transition and Fibrogenic Repair in Nonalcoholic Fatty Liver Disease

(2009) Wing–Kin Syn et al.   GASTROENTEROLOGY

The Hedgehog Pathway Transcription Factor GLI1 Promotes Malignant Behavior of Cancer Cells by Up-regulating Osteopontin

(2009) Shamik Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Similarities and Differences in the Pathogenesis of Alcoholic and Nonalcoholic Steatohepatitis

(2009) Wing-Kin Syn et al.   SEMINARS IN LIVER DISEASE

The Adventures of Sonic Hedgehog in Development and Repair. II. Sonic hedgehog and liver development, inflammation, and cancer

(2008) Alessia Omenetti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Liver Cell–Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

(2008) Rafal P. Witek et al.   GASTROENTEROLOGY

Osteopontin as two-sided mediator of intestinal inflammation

(2008) Katja Heilmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

(2008) Ryoichi Mori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Animal models of NASH: Getting both pathology and metabolic context right

(2008) Claire Z Larter et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY