标题
New concepts in opioid analgesia
作者
关键词
-
出版物
EXPERT OPINION ON INVESTIGATIONAL DRUGS
Volume -, Issue -, Pages 1-11
出版商
Informa UK Limited
发表日期
2018-08-28
DOI
10.1080/13543784.2018.1516204
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The novel μ-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception
- (2018) Rob Hill et al. BRITISH JOURNAL OF PHARMACOLOGY
- Pharmacogenomics of GPCR Drug Targets
- (2018) Alexander S. Hauser et al. CELL
- Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression
- (2018) Mohammad Zafar Imam et al. NEUROPHARMACOLOGY
- Analgesic Effects of A Novel Ph-Dependent μ-Opioid Receptor Agonist in Models of Neuropathic and Abdominal Pain
- (2018) Antonio Rodriguez-Gaztelumendi et al. PAIN
- Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist
- (2018) Viola Spahn et al. Scientific Reports
- Preclinical efficacy studies in investigator brochures: Do they enable risk–benefit assessment?
- (2018) Susanne Wieschowski et al. PLOS BIOLOGY
- Targeting delta opioid receptors for pain treatment: drugs in phase I and II clinical development
- (2017) Viola Spahn et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- New Data on Opioid Use and Prescribing in the United States
- (2017) Anne Schuchat et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Effects of acute and repeated treatment with the biased mu opioid receptor agonist TRV130 (oliceridine) on measures of antinociception, gastrointestinal function, and abuse liability in rodents
- (2017) Ahmad A Altarifi et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia
- (2017) Gregory Corder et al. NATURE MEDICINE
- Breaking barriers to novel analgesic drug development
- (2017) Ajay S. Yekkirala et al. NATURE REVIEWS DRUG DISCOVERY
- Opioid misuse in gastroenterology and non-opioid management of abdominal pain
- (2017) Eva Szigethy et al. Nature Reviews Gastroenterology & Hepatology
- Brain imaging tests for chronic pain: medical, legal and ethical issues and recommendations
- (2017) Karen D. Davis et al. Nature Reviews Neurology
- Drug Companies’ Liability for the Opioid Epidemic
- (2017) Rebecca L. Haffajee et al. NEW ENGLAND JOURNAL OF MEDICINE
- Addressing the Opioid Epidemic — Opportunities in the Postmarketing Setting
- (2017) Bruce M. Psaty et al. NEW ENGLAND JOURNAL OF MEDICINE
- Abuse-Deterrent Opioid Formulations — Putting the Potential Benefits into Perspective
- (2017) William C. Becker et al. NEW ENGLAND JOURNAL OF MEDICINE
- A nontoxic pain killer designed by modeling of pathological receptor conformations
- (2017) V. Spahn et al. SCIENCE
- Designing Safer Analgesics via μ-Opioid Receptor Pathways
- (2017) H.C. Stephen Chan et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Polyglycerol-opioid conjugate produces analgesia devoid of side effects
- (2017) Sara González-Rodríguez et al. eLife
- Species differences in the effects of the κ-opioid receptor antagonist zyklophin
- (2016) Sunil Sirohi et al. ALCOHOL
- G-protein–gated Inwardly Rectifying Potassium Channels Modulate Respiratory Depression by Opioids
- (2016) Gaspard Montandon et al. ANESTHESIOLOGY
- Opioid Receptors
- (2016) Christoph Stein Annual Review of Medicine
- Leukocyte opioid receptors mediate analgesia via Ca 2+ -regulated release of opioid peptides
- (2016) Melih Ö. Celik et al. BRAIN BEHAVIOR AND IMMUNITY
- Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia † †This Article is accompanied by Editorial Aew050.
- (2016) M Comelon et al. BRITISH JOURNAL OF ANAESTHESIA
- CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
- (2016) Deborah Dowell et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Will peripherally restricted kappa-opioid receptor agonists (pKORAs) relieve pain with less opioid adverse effects and abuse potential?
- (2016) A. Albert-Vartanian et al. JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
- Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council
- (2016) Roger Chou et al. JOURNAL OF PAIN
- Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators
- (2016) Andrew C. Kruegel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A randomized, phase 2 study investigating TRV130, a biased ligand of the μ-opioid receptor, for the intravenous treatment of acute pain
- (2016) Eugene R. Viscusi et al. PAIN
- Postoperative Opioid-induced Respiratory Depression
- (2015) Lorri A. Lee et al. ANESTHESIOLOGY
- Single Amino Acid Variation Underlies Species-Specific Sensitivity to Amphibian Skin-Derived Opioid-like Peptides
- (2015) Eyal Vardy et al. CHEMISTRY & BIOLOGY
- Intestinal inflammation and pain management
- (2015) Lilian Basso et al. CURRENT OPINION IN PHARMACOLOGY
- Intraoperative Use of Remifentanil for TIVA: Postoperative Pain, Acute Tolerance, and Opioid-Induced Hyperalgesia
- (2015) Martin S. Angst JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA
- Reproducibility: Standardize antibodies used in research
- (2015) Andrew Bradbury et al. NATURE
- Rates of opioid misuse, abuse, and addiction in chronic pain
- (2015) Kevin E. Vowles et al. PAIN
- Opioid-induced hyperalgesia in patients after surgery: a systematic review and a meta-analysis
- (2014) D. Fletcher et al. BRITISH JOURNAL OF ANAESTHESIA
- Analgesic efficacy of opioids in chronic pain: recent meta-analyses
- (2014) H Reinecke et al. BRITISH JOURNAL OF PHARMACOLOGY
- Identifying ligand-specific signalling within biased responses: focus on δ opioid receptor ligands
- (2014) I Charfi et al. BRITISH JOURNAL OF PHARMACOLOGY
- β-Arrestin-2-Biased Agonism of Delta Opioid Receptors Sensitizes Transient Receptor Potential Vanilloid Type 1 (TRPV1) in Primary Sensory Neurons
- (2014) Matthew P Rowan et al. Molecular Pain
- Peripheral gating of pain signals by endogenous lipid mediators
- (2014) Daniele Piomelli et al. NATURE NEUROSCIENCE
- Peripheral opioid receptor blockade increases postoperative morphine demands—A randomized, double-blind, placebo-controlled trial
- (2014) Christina Jagla et al. PAIN
- Peripheral input and its importance for central sensitization
- (2013) Ralf Baron et al. ANNALS OF NEUROLOGY
- Single-Dose Intra-Articular Morphine After Arthroscopic Knee Surgery: A Meta-Analysis of Randomized Placebo-Controlled Studies
- (2013) Chao Zeng et al. ARTHROSCOPY-THE JOURNAL OF ARTHROSCOPIC AND RELATED SURGERY
- Targeting novel peripheral mediators for the treatment of chronic pain
- (2013) N Richards et al. BRITISH JOURNAL OF ANAESTHESIA
- The K+channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia
- (2013) Dinah Nockemann et al. EMBO Molecular Medicine
- Opioids, sensory systems and chronic pain
- (2013) Christoph Stein EUROPEAN JOURNAL OF PHARMACOLOGY
- Sequestered naltrexone in sustained release morphine or oxycodone – a way to inhibit illicit use?
- (2013) Robert B Raffa et al. Expert Opinion On Drug Safety
- First Clinical Experience With TRV130: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers
- (2013) David G. Soergel et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Classification and definition of misuse, abuse, and related events in clinical trials: ACTTION systematic review and recommendations
- (2013) Shannon M. Smith et al. PAIN
- Opioid withdrawal increases transient receptor potential vanilloid 1 activity in a protein kinase A-dependent manner
- (2013) Viola Spahn et al. PAIN
- How are topical opioids used to manage painful cutaneous lesions in palliative care? A critical review
- (2013) Tanya Graham et al. PAIN
- µ-opioid receptor gene variantOPRM1118 A>G: a summary of its molecular and clinical consequences for pain
- (2013) Carmen Walter et al. PHARMACOGENOMICS
- Functional Characteristics of the Naked Mole Rat μ-Opioid Receptor
- (2013) Melanie Busch-Dienstfertig et al. PLoS One
- Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities
- (2013) I. Tabas et al. SCIENCE
- Opioid receptors: toward separation of analgesic from undesirable effects
- (2013) Ping-Yee Law et al. TRENDS IN BIOCHEMICAL SCIENCES
- Targeting inflammation and wound healing by opioids
- (2013) Christoph Stein et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?
- (2013) Elisa Mura et al. Journal of Pain Research
- Regulation of CaV2 calcium channels by G protein coupled receptors
- (2012) Gerald W. Zamponi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Pain inhibition by blocking leukocytic and neuronal opioid peptidases in peripheral inflamed tissue
- (2012) Anja Schreiter et al. FASEB JOURNAL
- Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain
- (2012) Bernard P. Roques et al. NATURE REVIEWS DRUG DISCOVERY
- Modulating Pain in the Periphery
- (2012) Srinivasa N. Raja REGIONAL ANESTHESIA AND PAIN MEDICINE
- Dual Peripheral Actions of Immune Cells in Neuropathic Pain
- (2011) Halina Machelska ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Predictive validity of behavioural animal models for chronic pain
- (2011) Odd-Geir Berge BRITISH JOURNAL OF PHARMACOLOGY
- Modulation of Peripheral Sensory Neurons by the Immune System: Implications for Pain Therapy
- (2011) C. Stein et al. PHARMACOLOGICAL REVIEWS
- Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease
- (2010) Christian Lüscher et al. NATURE REVIEWS NEUROSCIENCE
- The necessity of animal models in pain research
- (2010) Jeffrey S. Mogil et al. PAIN
- Coexpression of - and -opioid receptors in nociceptive sensory neurons
- (2010) H.-B. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cellular and Molecular Mechanisms of Pain
- (2009) Allan I. Basbaum et al. CELL
- Peripheral Non-Viral MIDGE Vector-Driven Delivery of β-Endorphin in Inflammatory Pain
- (2009) Halina Machelska et al. Molecular Pain
- Do Opioids Induce Hyperalgesia in Humans? An Evidence-Based Structured Review
- (2009) David A. Fishbain et al. PAIN MEDICINE
- Pain and the immune system
- (2008) H.L. Rittner et al. BRITISH JOURNAL OF ANAESTHESIA
- Opioids and the control of respiration
- (2008) K.T.S. Pattinson BRITISH JOURNAL OF ANAESTHESIA
- -Opioid Receptor-Mediated Depression of the Hypothalamic Hypocretin/Orexin Arousal System
- (2008) Y. Li et al. JOURNAL OF NEUROSCIENCE
- Morphine-6-glucuronide (M6G) for postoperative pain relief
- (2007) Albert Dahan et al. EUROPEAN JOURNAL OF PAIN
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started