The K+channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia

Loss of Neuronal Potassium/Chloride Cotransporter 3 (KCC3) Is Responsible for the Degenerative Phenotype in a Conditional Mouse Model of Hereditary Motor and Sensory Neuropathy Associated with Agenesis of the Corpus Callosum

(2012) M. Shekarabi et al.   JOURNAL OF NEUROSCIENCE

Gene therapy for the treatment of chronic peripheral nervous system pain

(2012) William F. Goins et al.   NEUROBIOLOGY OF DISEASE

Nav1.8 expression is not restricted to nociceptors in mouse peripheral nervous system

(2012) Shannon D. Shields et al.   PAIN

Immune cell–derived opioids protect against neuropathic pain in mice

(2011) Dominika Labuz et al.   JOURNAL OF CLINICAL INVESTIGATION

Mouse genomic variation and its effect on phenotypes and gene regulation

(2011) Thomas M. Keane et al.   NATURE

Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia

(2011) Claire Gaveriaux-Ruff et al.   PAIN

Immune conditions associated with CD4+ T effector-induced opioid release and analgesia

(2011) Jérôme Boué et al.   PAIN

Modulation of Peripheral Sensory Neurons by the Immune System: Implications for Pain Therapy

(2011) C. Stein et al.   PHARMACOLOGICAL REVIEWS

Nonenzymatic Rapid Control of GIRK Channel Function by a G Protein-Coupled Receptor Kinase

(2010) Adi Raveh et al.   CELL

Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease

(2010) Christian Lüscher et al.   NATURE REVIEWS NEUROSCIENCE

Coexpression of  - and  -opioid receptors in nociceptive sensory neurons

(2010) H.-B. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphine peripheral analgesia depends on activation of the PI3K /AKT/nNOS/NO/KATP signaling pathway

(2010) T. M. Cunha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissociation of the Opioid Receptor Mechanisms that Control Mechanical and Heat Pain

(2009) Grégory Scherrer et al.   CELL

Animal models of pain: progress and challenges

(2009) Jeffrey S. Mogil   NATURE REVIEWS NEUROSCIENCE

Involvement of Gi/o proteins and GIRK channels in the potentiation of morphine-induced spinal analgesia in acutely inflamed mice

(2009) Sara González-Rodríguez et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain

(2009) Ilona Obara et al.   PAIN

The Contribution of TRPM8 and TRPA1 Channels to Cold Allodynia and Neuropathic Pain

(2009) Ombretta Caspani et al.   PLoS One

Neuronal activity regulates phosphorylation-dependent surface delivery of G protein-activated inwardly rectifying potassium channels

(2009) H. J. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli

(2009) D. J. Cavanaugh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tolerance to the antinociceptive effects of peripherally administered opioids

(2008) Laura Hernández et al.   BRAIN RESEARCH

Distinct inhibition of voltage-activated Ca2+ channels by δ-opioid agonists in dorsal root ganglion neurons devoid of functional T-type Ca2+ currents

(2008) Z.-Z. Wu et al.   NEUROSCIENCE

Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes

(2008) Shad B. Smith et al.   Pharmacogenetics and Genomics