The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events
出版年份 2014 全文链接
标题
The use of mode of action information in risk assessment: Quantitative key events/dose-response framework for modeling the dose-response for key events
作者
关键词
-
出版物
CRITICAL REVIEWS IN TOXICOLOGY
Volume 44, Issue sup3, Pages 17-43
出版商
Informa UK Limited
发表日期
2014-07-29
DOI
10.3109/10408444.2014.931925
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A mechanistic redefinition of adverse effects – a key step in the toxicity testing paradigm shift
- (2016) Kim Boekelheide ALTEX-Alternatives to Animal Experimentation
- Courage for simplification and imperfection in the 21st century assessment of “Endocrine disruption”
- (2016) Daniel Dietrich ALTEX-Alternatives to Animal Experimentation
- In Vitroand Modelling Approaches to Risk Assessment from the U.S. Environmental Protection Agency ToxCast Programme
- (2014) Richard Judson et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Mode of action human relevance (species concordance) framework: Evolution of the Bradford Hill considerations and comparative analysis of weight of evidence
- (2014) M. E. Bette Meek et al. JOURNAL OF APPLIED TOXICOLOGY
- On mapping the human toxome
- (2014) Thomas Hartung ALTEX-Alternatives to Animal Experimentation
- Dose–response approaches for nuclear receptor-mediated modes of action for liver carcinogenicity: Results of a workshop
- (2013) Melvin E. Andersen et al. CRITICAL REVIEWS IN TOXICOLOGY
- Shape and steepness of toxicological dose–response relationships of continuous endpoints
- (2013) Wout Slob et al. CRITICAL REVIEWS IN TOXICOLOGY
- Mode of action and dose–response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study
- (2013) R. A. Budinsky et al. CRITICAL REVIEWS IN TOXICOLOGY
- Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study
- (2013) J. Christopher Corton et al. CRITICAL REVIEWS IN TOXICOLOGY
- Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator
- (2013) Clifford R. Elcombe et al. CRITICAL REVIEWS IN TOXICOLOGY
- A chronic oral reference dose for hexavalent chromium-induced intestinal cancer
- (2013) Chad M. Thompson et al. JOURNAL OF APPLIED TOXICOLOGY
- New developments in the evolution and application of the WHO/IPCS framework on mode of action/species concordance analysis
- (2013) M. E. Meek et al. JOURNAL OF APPLIED TOXICOLOGY
- Urinary Free Bisphenol A and Bisphenol A-Glucuronide Concentrations in Newborns
- (2013) Rebecca M. Nachman et al. JOURNAL OF PEDIATRICS
- 11β-Hydroxysteroid Dehydrogenases: Intracellular Gate-Keepers of Tissue Glucocorticoid Action
- (2013) Karen Chapman et al. PHYSIOLOGICAL REVIEWS
- Genomic responses in mouse models poorly mimic human inflammatory diseases
- (2013) Junhee Seok et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Use and validation of HT/HC assays to support 21st century toxicity evaluations
- (2013) Grace Patlewicz et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices
- (2013) J. Craig Rowlands et al. TOXICOLOGICAL SCIENCES
- Incorporating New Technologies Into Toxicity Testing and Risk Assessment: Moving From 21st Century Vision to a Data-Driven Framework
- (2013) Russell S. Thomas et al. TOXICOLOGICAL SCIENCES
- The adverse outcome pathway concept: A pragmatic tool in toxicology
- (2013) Mathieu Vinken TOXICOLOGY
- Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium
- (2012) C.R. Kirman et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Ontogeny of Hepatic Glucuronidation; Methods and Results
- (2012) Elke H.J. Krekels et al. CURRENT DRUG METABOLISM
- Relationship of Creatinine and Nutrition with Arsenic Metabolism
- (2012) Mary V. Gamble et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Concentrations of Bisphenol A and Seven Other Phenols in Pooled Sera from 3–11 Year Old Children: 2001–2002 National Health and Nutrition Examination Survey
- (2012) Xiaoyun Ye et al. ENVIRONMENTAL SCIENCE & TECHNOLOGY
- Critical review of dose–response options for F344 rat mammary tumors for acrylamide – Additional insights based on mode of action
- (2012) Andrew Maier et al. FOOD AND CHEMICAL TOXICOLOGY
- A review of dietary and non-dietary exposure to bisphenol-A
- (2012) Tinne Geens et al. FOOD AND CHEMICAL TOXICOLOGY
- Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project
- (2012) Katharine Briggs et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Identification of Location and Kinetically Defined Mechanism of Cofactors and Reporter Genes in the Cascade of Steroid-regulated Transactivation
- (2012) John A. Blackford et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- PA1 Protein, a New Competitive Decelerator Acting at More than One Step to Impede Glucocorticoid Receptor-mediated Transactivation
- (2012) Zhenhuan Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mode of Action: Moving toward a More Relevant and Efficient Assessment Paradigm
- (2012) Vicki Dellarco et al. JOURNAL OF NUTRITION
- Deducing the Temporal Order of Cofactor Function in Ligand-Regulated Gene Transcription: Theory and Experimental Verification
- (2012) Edward J. Dougherty et al. PLoS One
- Acetylcholinesterase inhibition dose–response modeling for chlorpyrifos and chlorpyrifos-oxon
- (2012) Richard Reiss et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Preliminary evaluation of the human relevance of respiratory tumors observed in rodents exposed to naphthalene
- (2012) Vincent J. Piccirillo et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Regulatory Forum Opinion Piece
- (2012) Gio Batta Gori TOXICOLOGIC PATHOLOGY
- A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening
- (2012) Russell S. Thomas et al. TOXICOLOGICAL SCIENCES
- Paused RNA Polymerase II as a Developmental Checkpoint
- (2011) Michael Levine CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A
- (2011) J. G. Hengstler et al. CRITICAL REVIEWS IN TOXICOLOGY
- Historical perspective on the use of animal bioassays to predict carcinogenicity: Evolution in design and recognition of utility
- (2011) L. A. Beyer et al. CRITICAL REVIEWS IN TOXICOLOGY
- In Vitro Age-Dependent Enzymatic Metabolism of Chlorpyrifos and Chlorpyrifos-Oxon in Human Hepatic Microsomes and Chlorpyrifos-Oxon in Plasma
- (2011) J. N. Smith et al. DRUG METABOLISM AND DISPOSITION
- The Development of UDP-Glucuronosyltransferases 1A1 and 1A6 in the Pediatric Liver
- (2011) S. J. Miyagi et al. DRUG METABOLISM AND DISPOSITION
- UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables
- (2011) S. L. Navarro et al. DRUG METABOLISM AND DISPOSITION
- The road less traveled: New views of steroid receptor action from the path of dose–response curves
- (2011) S. Stoney Simons et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
- (2011) Sam John et al. NATURE GENETICS
- Application of a source-to-outcome model for the assessment of health impacts from dietary exposures to insecticide residues
- (2011) Paul S. Price et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Development of a source-to-outcome model for dietary exposures to insecticide residues: An example using chlorpyrifos
- (2011) Paul M. Hinderliter et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- The human relevant potency threshold: Reducing uncertainty by human calibration of cumulative risk assessments
- (2011) C.J. Borgert et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Toxicology and Epidemiology: Improving the Science with a Framework for Combining Toxicological and Epidemiological Evidence to Establish Causal Inference
- (2011) Hans-Olov Adami et al. TOXICOLOGICAL SCIENCES
- Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans
- (2011) Jeffrey W. Fisher et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: The hunt goes on
- (2010) Lucio G. Costa et al. BIOCHEMICAL PHARMACOLOGY
- Hypothesis-based weight of evidence: A tool for evaluating and communicating uncertainties and inconsistencies in the large body of evidence in proposing a carcinogenic mode of action—naphthalene as an example
- (2010) Lorenz R. Rhomberg et al. CRITICAL REVIEWS IN TOXICOLOGY
- Glucocorticoid receptor cofactors as therapeutic targets
- (2010) S Stoney Simons Jr CURRENT OPINION IN PHARMACOLOGY
- Differences between Human and Rat Intestinal and Hepatic Bisphenol A Glucuronidation and the Influence of Alamethicin on In Vitro Kinetic Measurements
- (2010) C. S. Mazur et al. DRUG METABOLISM AND DISPOSITION
- Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
- (2010) Gerald T. Ankley et al. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
- Mechanisms of Progesterone Receptor Inhibition of Inflammatory Responses in Cellular Models of Breast Cancer
- (2010) Sakiko Kobayashi et al. MOLECULAR ENDOCRINOLOGY
- A theoretical framework for gene induction and experimental comparisons
- (2010) K. M. Ong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Uterine epithelial estrogen receptor is dispensable for proliferation but essential for complete biological and biochemical responses
- (2010) W. Winuthayanon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Use of read-across and tiered exposure assessment in risk assessment under REACH – A case study on a phase-in substance
- (2010) S.R. Vink et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Human and Rat Primary Hepatocyte CYP1A1 and 1A2 Induction with 2,3,7,8-Tetrachlorodibenzo-p-dioxin, 2,3,7,8-Tetrachlorodibenzofuran, and 2,3,4,7,8-Pentachlorodibenzofuran
- (2010) Robert A. Budinsky et al. TOXICOLOGICAL SCIENCES
- Chemical Carcinogenesis
- (2010) S. M. Cohen et al. TOXICOLOGICAL SCIENCES
- Longitudinal changes in PON1 enzymatic activities in Mexican–American mothers and children with different genotypes and haplotypes
- (2010) Karen Huen et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Relationship between estrogen receptor α location and gene induction reveals the importance of downstream sites and cofactors
- (2009) Fabio Parisi et al. BMC GENOMICS
- Cruciferous Vegetable Feeding Alters UGT1A1 Activity: Diet- and Genotype-Dependent Changes in Serum Bilirubin in a Controlled Feeding Trial
- (2009) S. L. Navarro et al. Cancer Prevention Research
- Application of Key Events Analysis to Chemical Carcinogens and Noncarcinogens
- (2009) Alan R. Boobis et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- Application of a Key Events Dose-Response Analysis to Nutrients: A Case Study with Vitamin A (Retinol)
- (2009) A. Catharine Ross et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- The Key Events Dose-Response Framework: A Foundation for Examining Variability in Elicitation Thresholds for Food Allergens
- (2009) Steve L. Taylor et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- The Key Events Dose-Response Framework: Its Potential for Application to Foodborne Pathogenic Microorganisms
- (2009) Robert L. Buchanan † et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- The Key Events Dose-Response Framework: A Cross-Disciplinary Mode-of-Action Based Approach to Examining Dose-Response and Thresholds
- (2009) Elizabeth Julien* et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- UGT genomic diversity: beyond gene duplication
- (2009) Chantal Guillemette et al. DRUG METABOLISM REVIEWS
- Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system
- (2009) Michael H. Court DRUG METABOLISM REVIEWS
- Paraoxonase status and plasma butyrylcholinesterase activity in chlorpyrifos manufacturing workers
- (2009) James W Albers et al. Journal of Exposure Science and Environmental Epidemiology
- Citrus Fruit Intake Is Associated with Lower Serum Bilirubin Concentration among Women with the UGT1A1*28 Polymorphism
- (2009) Misty R. Saracino et al. JOURNAL OF NUTRITION
- Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose–response relationships, exemplified for mutagenicity data
- (2009) Werner K. Lutz et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Importance of steroid receptor coactivators in the modulation of steroid action on brain and behavior
- (2009) Thierry D. Charlier PSYCHONEUROENDOCRINOLOGY
- In Vivo Glucuronidation Activity of Drugs in Neonates: Extensive Interindividual Variability Despite Their Young Age
- (2009) Karel Allegaert et al. THERAPEUTIC DRUG MONITORING
- Toxicity Testing in the 21st Century: Using the New Toxicity Testing Paradigm to Create a Taxonomy of Adverse Effects
- (2009) Kim Boekelheide et al. TOXICOLOGICAL SCIENCES
- Estimates of Cancer Potency of 2,3,7,8-Tetrachlorodibenzo(p)dioxin Using Linear and Nonlinear Dose-Response Modeling and Toxicokinetics
- (2009) Ted Simon et al. TOXICOLOGICAL SCIENCES
- Bisphenol A levels in blood depend on age and exposure
- (2009) Hans Mielke et al. TOXICOLOGY LETTERS
- What goes on behind closed doors: physiological versus pharmacological steroid hormone actions
- (2008) S. Stoney Simons BIOESSAYS
- IPCS Framework for Analyzing the Relevance of a Noncancer Mode of Action for Humans
- (2008) Alan R. Boobis et al. CRITICAL REVIEWS IN TOXICOLOGY
- Recent developments in frameworks to consider human relevance of hypothesized modes of action for tumours in animals
- (2008) M.E. Bette Meek ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Exposure to Bisphenol A and Other Phenols in Neonatal Intensive Care Unit Premature Infants
- (2008) Antonia M. Calafat et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Predicting Plasma Concentrations of Bisphenol A in Children Younger Than 2 Years of Age after Typical Feeding Schedules, using a Physiologically Based Toxicokinetic Model
- (2008) Andrea N. Edginton et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- The Hill equation: a review of its capabilities in pharmacological modelling
- (2008) Sylvain Goutelle et al. FUNDAMENTAL & CLINICAL PHARMACOLOGY
- Consumption of Wonderful Variety Pomegranate Juice and Extract by Diabetic Patients Increases Paraoxonase 1 Association with High-Density Lipoprotein and Stimulates Its Catalytic Activities
- (2008) Wasseem Rock et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Cholinesterase inhibition in chlorpyrifos workers: Characterization of biomarkers of exposure and response in relation to urinary TCPy
- (2008) David H Garabrant et al. Journal of Exposure Science and Environmental Epidemiology
- Derivation of a Bisphenol a Oral Reference Dose (RfD) and Drinking-Water Equivalent Concentration∗
- (2008) Calvin C. Willhite et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- Modulation of transcription parameters in glucocorticoid receptor-mediated repression
- (2008) Yunguang Sun et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- A Physiologically based Pharmacokinetic Model for Intravenous and Ingested Dimethylarsinic Acid in Mice
- (2008) Marina V. Evans et al. TOXICOLOGICAL SCIENCES
- Thermodynamic basis for expressing dose logarithmically
- (2008) W WADDELL TOXICOLOGY AND APPLIED PHARMACOLOGY
- Paraoxonase 1 (PON1) status and substrate hydrolysis
- (2008) Rebecca J. Richter et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started