FutureTox: Building the Road for 21st Century Toxicology and Risk Assessment Practices

A toxicology ontology roadmap

(2014) Barry Hardy   ALTEX-Alternatives to Animal Experimentation

The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans

(2014) Bas Blaauboer   ALTEX-Alternatives to Animal Experimentation

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing

(2014) David Basketter   ALTEX-Alternatives to Animal Experimentation

Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology

(2012) A Rostami-Hodjegan   CLINICAL PHARMACOLOGY & THERAPEUTICS

Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System

(2012) Richard S. Judson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cross-species Comparisons of Transcriptomic Alterations in Human and Rat Primary Hepatocytes Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

(2012) Michael B. Black et al.   TOXICOLOGICAL SCIENCES

Quantitative High-Throughput Screening for Chemical Toxicity in a Population-Based In Vitro Model

(2012) Eric F. Lock et al.   TOXICOLOGICAL SCIENCES

A Comprehensive Statistical Analysis of Predicting In Vivo Hazard Using High-Throughput In Vitro Screening

(2012) Russell S. Thomas et al.   TOXICOLOGICAL SCIENCES

Alternatives to animal testing: current status and future perspectives

(2011) Manfred Liebsch et al.   ARCHIVES OF TOXICOLOGY

Estimating Toxicity-Related Biological Pathway Altering Doses for High-Throughput Chemical Risk Assessment

(2011) Richard S. Judson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment

(2011) Barbara A. Wetmore et al.   TOXICOLOGICAL SCIENCES

Multimedia modeling of human exposure to chemical substances: The roles of food web biomagnification and biotransformation

(2010) Jon A. Arnot et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Incorporating Human Dosimetry and Exposure into High-Throughput In Vitro Toxicity Screening

(2010) Daniel M. Rotroff et al.   TOXICOLOGICAL SCIENCES

In Vitro Screening for Population Variability in Chemical Toxicity

(2010) Shannon H. O'Shea et al.   TOXICOLOGICAL SCIENCES

A Framework for Assessing Inter-individual Variability in Pharmacokinetics Using Virtual Human Populations and Integrating General Knowledge of Physical Chemistry, Biology, Anatomy, Physiology and Genetics: A Tale of ‘Bottom-Up’ vs ‘Top-Down’ Recognition of Covariates

(2009) Masoud Jamei et al.   Drug Metabolism and Pharmacokinetics

Physicochemical drug properties associated within vivotoxicological outcomes: a review

(2009) David A Price et al.   Expert Opinion on Drug Metabolism & Toxicology

Variability of urinary concentrations of polycyclic aromatic hydrocarbon metabolite in general population and comparison of spot, first-morning and 24-h void sampling

(2009) Zheng Li et al.   Journal of Exposure Science and Environmental Epidemiology

Building a Model Based on Scientific Consensus for Life Cycle Impact Assessment of Chemicals: The Search for Harmony and Parsimony

(2008) Michael Z. Hauschild et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

(2008) Elissa J. Chesler et al.   MAMMALIAN GENOME