Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project

Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

(2011) Yen Low et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A Multiscale Simulation System for the Prediction of Drug-Induced Cardiotoxicity

(2011) Cristian Obiol-Pardo et al.   Journal of Chemical Information and Modeling

Use of Genotoxicity Information in the Development of Integrated Testing Strategies (ITS) for Skin Sensitization

(2010) Ovanes Mekenyan et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Developing Structure−Activity Relationships for the Prediction of Hepatotoxicity

(2010) Nigel Greene et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Probabilistic Risk Analysis: Improving Early Drug Development Decision Making

(2010) P N Mudd et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The computational prediction of genotoxicity

(2010) Russell T Naven et al.   Expert Opinion on Drug Metabolism & Toxicology

Hepatotoxicity and hepatic metabolism of available drugs: current problems and possible solutions in preclinical stages

(2010) Shibashish Giri et al.   Expert Opinion on Drug Metabolism & Toxicology

Anticipating drug side effects by comparative pharmacology

(2010) Ricard Garcia-Serna et al.   Expert Opinion on Drug Metabolism & Toxicology

Oral LD50 toxicity modeling and prediction of per- and polyfluorinated chemicals on rat and mouse

(2010) Barun Bhhatarai et al.   MOLECULAR DIVERSITY

Using In Silico Tools in a Weight of Evidence Approach to Aid Toxicological Assessment

(2010) Claire M. Ellison et al.   Molecular Informatics

Nuclear receptors as drug targets in cholestasis and drug-induced hepatotoxicity

(2010) Gernot Zollner et al.   PHARMACOLOGY & THERAPEUTICS

Collaborative development of predictive toxicology applications

(2010) Barry Hardy et al.   Journal of Cheminformatics

Quantitative Structure−Activity Relationship Modeling of Rat Acute Toxicity by Oral Exposure

(2009) Hao Zhu et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Handing over the baton: Connecting medicinal chemistry with process R&D

(2009) H.-J. Federsel   DRUG NEWS & PERSPECTIVES

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME–Tox)

(2008) Gergely Szakács et al.   DRUG DISCOVERY TODAY

The role of hepatic transporters in drug elimination

(2008) Christoph Funk   Expert Opinion on Drug Metabolism & Toxicology

The hERG potassium channel and hERG screening for drug-induced torsades de pointes

(2008) Jules C. Hancox et al.   PHARMACOLOGY & THERAPEUTICS

Toxicity Data Informatics: Supporting a New Paradigm for Toxicity Prediction

(2008) Ann M. Richard et al.   TOXICOLOGY MECHANISMS AND METHODS

Development of a Phospholipidosis Database and Predictive Quantitative Structure-Activity Relationship (QSAR) Models

(2008) Naomi L. Kruhlak et al.   TOXICOLOGY MECHANISMS AND METHODS

In Silico Tools for Sharing Data and Knowledge on Toxicity and Metabolism: Derek for Windows, Meteor, and Vitic

(2008) Carol A. Marchant et al.   TOXICOLOGY MECHANISMS AND METHODS