Interindividual variability in hepatic drug glucuronidation: studies into the role of age, sex, enzyme inducers, and genetic polymorphism using the human liver bank as a model system

Pharmacokinetics and drug metabolism in the elderly

(2009) Ulrich Klotz   DRUG METABOLISM REVIEWS

Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV-Coinfected Ghanaian Patients:UGT2B7*1c Is Associated With Faster Zidovudine Clearance and Glucuronidation

(2009) Awewura Kwara et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Single nucleotide polymorphism discovery and functional assessment of variation in the UDP-glucuronosyltransferase 2B7 gene

(2009) Federico Innocenti et al.   Pharmacogenetics and Genomics

Effect of Genetic Polymorphisms in UDP-Glucuronosyltransferase 1A6 (UGT1A6) on Acetylsalicylic Acid Metabolism in Healthy Female Volunteers

(2009) Martijn G.H. van Oijen et al.   PHARMACOLOGY

The Relationship Between the Response of Clinical Symptoms and Plasma Olanzapine Concentration, Based on Pharmacogenetics

(2009) Motohiro Nozawa et al.   THERAPEUTIC DRUG MONITORING

UGT1A6 genotype-related pharmacokinetics of deferiprone (L1) in healthy volunteers

(2008) Lie Michael George Limenta et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

(2008) S. Ohno et al.   DRUG METABOLISM AND DISPOSITION

Expression of UGT1A and UGT2B mRNA in Human Normal Tissues and Various Cell Lines

(2008) A. Nakamura et al.   DRUG METABOLISM AND DISPOSITION

Effect of Aging on Glucuronidation of Valproic Acid in Human Liver Microsomes and the Role of UDP-Glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10

(2008) U. A. Argikar et al.   DRUG METABOLISM AND DISPOSITION

Gender Has a Small but Statistically Significant Effect on Clearance of CYP3A Substrate Drugs

(2008) David J. Greenblatt et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Novel Polymorphic Human UDP-glucuronosyltransferase 2A3: Cloning, Functional Characterization of Enzyme Variants, Comparative Tissue Expression, and Gene Induction

(2008) M. H. Court et al.   MOLECULAR PHARMACOLOGY

Identification of a prevalent functional missense polymorphism in the UGT2B10 gene and its association with UGT2B10 inactivation against tobacco-specific nitrosamines

(2008) Gang Chen et al.   Pharmacogenetics and Genomics

Pharmacokinetics of mycophenolate mofetil and its glucuronide metabolites in healthy volunteers

(2008) Eric Lévesque et al.   PHARMACOGENOMICS

The ontogeny of drug metabolism enzymes and implications for adverse drug events

(2008) Ronald N. Hines   PHARMACOLOGY & THERAPEUTICS