mTOR dysregulation and tuberous sclerosis-related epilepsy

Increased expression of (immuno)proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway

(2017) Diede W. M. Broekaart et al.   EPILEPSIA

Neuroinflammatory targets and treatments for epilepsy validated in experimental models

(2017) Eleonora Aronica et al.   EPILEPSIA

Long-term outcomes of epilepsy surgery in tuberous sclerosis complex

(2017) Shuli Liang et al.   JOURNAL OF NEUROLOGY

Impact of clinical exomes in neurodevelopmental and neurometabolic disorders

(2017) Christina Evers et al.   MOLECULAR GENETICS AND METABOLISM

Molecular neurobiology of mTOR

(2017) Katarzyna Switon et al.   NEUROSCIENCE

Early Detection of Tuberous Sclerosis Complex: An Opportunity for Improved Neurodevelopmental Outcome

(2017) Clara W.T. Chung et al.   PEDIATRIC NEUROLOGY

The genomic landscape of tuberous sclerosis complex

(2017) Katie R. Martin et al.   Nature Communications

Subependymal giant cell astrocytomas in Tuberous Sclerosis Complex have consistent TSC1/TSC2 biallelic inactivation, and no BRAF mutations

(2017) Anika Bongaarts et al.   Oncotarget

Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

(2017) James D. Mills et al.   Scientific Reports

Systematic review and meta-analysis of differentially expressed miRNAs in experimental and human temporal lobe epilepsy

(2017) A. Korotkov et al.   Scientific Reports

Whole exome sequencing identifies the firstSTRADApoint mutation in a patient with polyhydramnios, megalencephaly, and symptomatic epilepsy syndrome (PMSE)

(2016) Weimin Bi et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Malformations of cortical development

(2016) Rahul S. Desikan et al.   ANNALS OF NEUROLOGY

Centre of epileptogenic tubers generate and propagate seizures in tuberous sclerosis

(2016) Lakshminarayanan Kannan et al.   BRAIN

Effects of rapamycin and curcumin treatment on the development of epilepsy after electrically induced status epilepticus in rats

(2016) Cato M. Drion et al.   EPILEPSIA

Resection of ictal high frequency oscillations is associated with favorable surgical outcome in pediatric drug resistant epilepsy secondary to tuberous sclerosis complex

(2016) Hisako Fujiwara et al.   EPILEPSY RESEARCH

Early onset epileptic encephalopathy or genetically determined encephalopathy with early onset epilepsy? Lessons learned from TSC

(2016) Paolo Curatolo et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Tuberous sclerosis complex as a model disease for developing new therapeutics for epilepsy

(2016) Anna Jeong et al.   Expert Review of Neurotherapeutics

Promoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC)

(2016) A. Fuso et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis complex (TSC): evidence from layer-specific marker expression

(2016) Angelika Mühlebner et al.   Journal of Neurodevelopmental Disorders

Dysregulation of the (immuno)proteasome pathway in malformations of cortical development

(2016) J. van Scheppingen et al.   Journal of Neuroinflammation

Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study

(2016) Jacqueline A French et al.   LANCET

Low-grade epilepsy-associated neuroepithelial tumours — the 2016 WHO classification

(2016) Ingmar Blümcke et al.   Nature Reviews Neurology

The mTOR signalling cascade: paving new roads to cure neurological disease

(2016) Peter B. Crino   Nature Reviews Neurology

Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions

(2016) Gabriele Ruffolo et al.   NEUROBIOLOGY OF DISEASE

Sirolimus for epilepsy in children with tuberous sclerosis complex

(2016) Iris E. Overwater et al.   NEUROLOGY

Long-term treatment of epilepsy with everolimus in tuberous sclerosis

(2016) Darcy A. Krueger et al.   NEUROLOGY

Crucial role of astrocytes in temporal lobe epilepsy

(2016) C. Steinhäuser et al.   NEUROSCIENCE

Efficacy and safety of Everolimus in children with TSC - associated epilepsy – Pilot data from an open single-center prospective study

(2016) Sharon Samueli et al.   Orphanet Journal of Rare Diseases

Challenges in the clinical development of new antiepileptic drugs

(2016) Valentina Franco et al.   PHARMACOLOGICAL RESEARCH

The role of mTOR signalling in neurogenesis, insights from tuberous sclerosis complex

(2016) Andrew R. Tee et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mammalian Target of Rapamycin: Its Role in Early Neural Development and in Adult and Aged Brain Function

(2016) Carla Garza-Lombó et al.   Frontiers in Cellular Neuroscience

Common Mechanisms Underlying Epileptogenesis and the Comorbidities of Epilepsy

(2016) Andrey Mazarati et al.   Cold Spring Harbor Perspectives in Medicine

Tuberous sclerosis complex as a model disease for developing new therapeutics for epilepsy

(2016) Anna Jeong et al.   Expert Review of Neurotherapeutics

Association ofMTORMutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism

(2016) Ghayda M. Mirzaa et al.   JAMA Neurology

Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex

(2016) Angelika Mühlebner et al.   PLoS One

Familial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulatorNPRL3

(2015) Joe C. Sim et al.   ANNALS OF NEUROLOGY

Somatic Mutations in theMTORgene cause focal cortical dysplasia type IIb

(2015) Mitsuko Nakashima et al.   ANNALS OF NEUROLOGY

Familial focal epilepsy with focal cortical dysplasia due toDEPDC5mutations

(2015) Stéphanie Baulac et al.   ANNALS OF NEUROLOGY

Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia

(2015) Alissa M. D'Gama et al.   ANNALS OF NEUROLOGY

Targeted Next Generation Sequencing reveals previously unidentified TSC1 and TSC2 mutations

(2015) Mark Nellist et al.   BMC Medical Genetics

The enlarging spectrum of focal cortical dysplasias: Figure 1

(2015) Peter B. Crino   BRAIN

PI3K/AKT pathway mutations cause a spectrum of brain malformations from megalencephaly to focal cortical dysplasia

(2015) Laura A. Jansen et al.   BRAIN

Blood-brain barrier leakage after status epilepticus in rapamycin-treated rats I: Magnetic resonance imaging

(2015) Erwin A. van Vliet et al.   EPILEPSIA

Neurological and neuropsychiatric aspects of tuberous sclerosis complex

(2015) Paolo Curatolo et al.   LANCET NEUROLOGY

Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy

(2015) Jae Seok Lim et al.   NATURE MEDICINE

Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex

(2015) Bo Zhang et al.   NEUROBIOLOGY OF DISEASE

Comorbidities in Neurology: Is adenosine the common link?

(2015) Detlev Boison et al.   NEUROPHARMACOLOGY

Resective Epilepsy Surgery for Tuberous Sclerosis in Children

(2015) Aria Fallah et al.   NEUROSURGERY

Hemispherectomy for Hemimegalencephaly Due to Tuberous Sclerosis and a Review of the Literature

(2015) Vishnu Anand Cuddapah et al.   PEDIATRIC NEUROLOGY

Mechanistic Target of Rapamycin (mTOR) in Tuberous Sclerosis Complex-Associated Epilepsy

(2015) Paolo Curatolo   PEDIATRIC NEUROLOGY

Timing in Neural Maturation: Arrest, Delay, Precociousness, and Temporal Determination of Malformations

(2015) Harvey B. Sarnat et al.   PEDIATRIC NEUROLOGY

mTOR in Brain Physiology and Pathologies

(2015) Joël Bockaert et al.   PHYSIOLOGICAL REVIEWS

Malformations of Cortical Development and Epilepsy

(2015) A. J. Barkovich et al.   Cold Spring Harbor Perspectives in Medicine

Role of Astrocytes in Epilepsy

(2015) D. A. Coulter et al.   Cold Spring Harbor Perspectives in Medicine

mTOR Signaling in Epilepsy: Insights from Malformations of Cortical Development

(2015) P. B. Crino   Cold Spring Harbor Perspectives in Medicine

Epileptogenesis

(2015) Asla Pitkänen et al.   Cold Spring Harbor Perspectives in Medicine

Epileptogenic but MRI-normal perituberal tissue in Tuberous Sclerosis Complex contains tuber-specific abnormalities

(2015) Alexander A Sosunov et al.   Acta Neuropathologica Communications

Roles of mTOR Signaling in Brain Development

(2015) Da Yong Lee   Experimental Neurobiology

Megalencephaly and hemimegalencephaly: Breakthroughs in molecular etiology

(2014) Ghayda M. Mirzaa et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Untangling the pathomechanisms of temporal lobe epilepsy—The promise of epileptic biomarkers and novel therapeutic approaches

(2014) Tibor Szilágyi et al.   BRAIN RESEARCH BULLETIN

Focal dysplasia of the cerebral cortex and infantile spasms associated with somatic 1q21.1-q44 duplication including theAKT3gene

(2014) V. Conti et al.   CLINICAL GENETICS

Basic Mechanisms of Epileptogenesis in Pediatric Cortical Dysplasia

(2014) Sara Abdijadid et al.   CNS Neuroscience & Therapeutics

Interictal high frequency oscillations correlating with seizure outcome in patients with widespread epileptic networks in tuberous sclerosis complex

(2014) Tohru Okanishi et al.   EPILEPSIA

The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations

(2014) Filippo Sean Giorgi et al.   JOURNAL OF NEURAL TRANSMISSION

Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination

(2014) K. K. Bercury et al.   JOURNAL OF NEUROSCIENCE

Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination

(2014) F. Lebrun-Julien et al.   JOURNAL OF NEUROSCIENCE

Mammalian Target of Rapamycin Inhibitors for Intractable Epilepsy and Subependymal Giant Cell Astrocytomas in Tuberous Sclerosis Complex

(2014) Michael Cardamone et al.   JOURNAL OF PEDIATRICS

The Neurology of mTOR

(2014) Jonathan O. Lipton et al.   NEURON

Epilepsy Related to Developmental Tumors and Malformations of Cortical Development

(2014) Eleonora Aronica et al.   Neurotherapeutics

Past and Present Definitions of Epileptogenesis and Its Biomarkers

(2014) Asla Pitkänen et al.   Neurotherapeutics

Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model

(2014) N. Lozovaya et al.   Nature Communications

mTOR signaling and its roles in normal and abnormal brain development

(2014) Nobuyuki Takei et al.   Frontiers in Molecular Neuroscience

Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies

(2014) Joan Liu et al.   Acta Neuropathologica Communications

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

(2013) Christian Koelsche et al.   ACTA NEUROPATHOLOGICA

BRAFV600E mutation is a negative prognosticator in pediatric ganglioglioma

(2013) Sonika Dahiya et al.   ACTA NEUROPATHOLOGICA

Evolving neurobiology of tuberous sclerosis complex

(2013) Peter B. Crino   ACTA NEUROPATHOLOGICA

TORC1-dependent epilepsy caused by acute biallelicTsc1deletion in adult mice

(2013) Elisabeth Abs et al.   ANNALS OF NEUROLOGY

Everolimus treatment of refractory epilepsy in tuberous sclerosis complex

(2013) Darcy A. Krueger et al.   ANNALS OF NEUROLOGY

mTOR: A Link from the Extracellular Milieu to Transcriptional Regulation of Oligodendrocyte Development

(2013) Teresa L. Wood et al.   ASN Neuro

Epilepsy surgery for hemispheric syndromes in infants: Hemimegalencepahly and hemispheric cortical dysplasia

(2013) Christine Bulteau et al.   BRAIN & DEVELOPMENT

Dysembryoplastic Neuroepithelial Tumors Share with Pleomorphic Xanthoastrocytomas and Gangliogliomas BRAFV600EMutation and Expression

(2013) Céline Chappé et al.   BRAIN PATHOLOGY

BRAF V600E Mutation Is Associated with mTOR Signaling Activation in Glioneuronal Tumors

(2013) Avanita S. Prabowo et al.   BRAIN PATHOLOGY

Current management and surgical outcomes of medically intractable epilepsy

(2013) Wyatt L. Ramey et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Hemimegalencephaly, a paradigm for somatic postzygotic neurodevelopmental disorders

(2013) Seung Tae Baek et al.   CURRENT OPINION IN NEUROLOGY

Everolimus in tuberous sclerosis patients with intractable epilepsy: A treatment option?

(2013) Gert Wiegand et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

A critical review of mTOR inhibitors and epilepsy: from basic science to clinical trials

(2013) Michael Wong   Expert Review of Neurotherapeutics

Original article Hemimegalencephaly: foetal tauopathy with mTOR hyperactivation and neuronal lipidosis

(2013) Harvey Sarnat et al.   FOLIA NEUROPATHOLOGICA

A recollection of mTOR signaling in learning and memory

(2013) T. E. Graber et al.   LEARNING & MEMORY

Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis

(2013) Helen S. Bateup et al.   NEURON

Vigabatrin Inhibits Seizures and mTOR Pathway Activation in a Mouse Model of Tuberous Sclerosis Complex

(2013) Bo Zhang et al.   PLoS One

Rapamycin Prevents Seizures After Depletion of STRADA in a Rare Neurodevelopmental Disorder

(2013) W. E. Parker et al.   Science Translational Medicine

Cytoarchitectural alterations are widespread in cerebral cortex in tuberous sclerosis complex

(2012) Leah Marcotte et al.   ACTA NEUROPATHOLOGICA

A developmental and genetic classification for malformations of cortical development: update 2012

(2012) A. James Barkovich et al.   BRAIN

Malformations of Cortical Development

(2012) Eleonora Aronica et al.   BRAIN PATHOLOGY

Fetal Brain Lesions in Tuberous Sclerosis Complex: TORC1 Activation and Inflammation

(2012) Avanita S. Prabowo et al.   BRAIN PATHOLOGY

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Fetal Brain mTOR Signaling Activation in Tuberous Sclerosis Complex

(2012) Victoria Tsai et al.   CEREBRAL CORTEX

Finding a better drug for epilepsy: The mTOR pathway as an antiepileptogenic target

(2012) Aristea S. Galanopoulou et al.   EPILEPSIA

Management of epilepsy associated with tuberous sclerosis complex (TSC): Clinical recommendations

(2012) Paolo Curatolo et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Tuberous sclerosis and epilepsy: Role of astrocytes

(2012) Michael Wong et al.   GLIA

Astrocyte immune responses in epilepsy

(2012) Eleonora Aronica et al.   GLIA

The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex

(2012) Sharon W. Way et al.   HUMAN MOLECULAR GENETICS

mTOR Pathway Overactivation in BRAF Mutated Papillary Thyroid Carcinoma

(2012) Alexandra Faustino et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis

(2012) J. McMahon et al.   JOURNAL OF NEUROSCIENCE

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes

(2012) Jean-Baptiste Rivière et al.   NATURE GENETICS

De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly

(2012) Jeong Ho Lee et al.   NATURE GENETICS

Somatic Activation of AKT3 Causes Hemispheric Developmental Brain Malformations

(2012) Annapurna Poduri et al.   NEURON

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

(2011) Genevieve Schindler et al.   ACTA NEUROPATHOLOGICA

Cerebral expression of drug transporters in epilepsy

(2011) Eleonora Aronica et al.   ADVANCED DRUG DELIVERY REVIEWS

Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia

(2011) Delia M. Talos et al.   ANNALS OF NEUROLOGY

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway

(2011) Sharon S. McDaniel et al.   EPILEPSIA

Inflammation in epilepsy: Clinical observations

(2011) Eleonora Aronica et al.   EPILEPSIA

Long-term neurological outcome in children with early-onset epilepsy associated with tuberous sclerosis

(2011) Raffaella Cusmai et al.   EPILEPSY & BEHAVIOR

The use of MR imaging and spectroscopy of the brain in children investigated for developmental delay: What is the most appropriate imaging strategy?

(2011) Paul D. Griffiths et al.   EUROPEAN RADIOLOGY

Loss of Tsc1 In Vivo Impairs Hippocampal mGluR-LTD and Increases Excitatory Synaptic Function

(2011) H. S. Bateup et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

Enhanced GABAergic network and receptor function in pediatric cortical dysplasia Type IIB compared with Tuberous Sclerosis Complex

(2011) Carlos Cepeda et al.   NEUROBIOLOGY OF DISEASE

Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin

(2011) Robert P. Carson et al.   NEUROBIOLOGY OF DISEASE

mTOR: A pathogenic signaling pathway in developmental brain malformations

(2011) Peter B. Crino   TRENDS IN MOLECULAR MEDICINE

mTOR Signaling

(2011) M. Laplante et al.   Cold Spring Harbor Perspectives in Biology

Hemimegalencephaly: a fetal case with neuropathological confirmation and review of the literature

(2010) Branavan Manoranjan et al.   ACTA NEUROPATHOLOGICA

Tuberous sclerosis: A primary pathology of astrocytes?

(2010) Alexander A. Sosunov et al.   EPILEPSIA

Do tubers contain function? Resection of epileptogenic foci in perirolandic cortex in children with tuberous sclerosis complex

(2010) Yaron A. Moshel et al.   EPILEPSIA

Therapeutic approaches to epileptogenesis-Hope on the horizon

(2010) Asla Pitkänen   EPILEPSIA

Caveat mTOR: aberrant signaling disrupts corticogenesis

(2010) Lucy R. Osborne   JOURNAL OF CLINICAL INVESTIGATION

STRADα deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice

(2010) Ksenia A. Orlova et al.   JOURNAL OF CLINICAL INVESTIGATION

An international consensus classification for focal cortical dysplasias

(2010) Ingmar Blümcke et al.   LANCET NEUROLOGY

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas

(2010) Margaret J. Dougherty et al.   NEURO-ONCOLOGY

Modulation of astrocyte glutamate transporters decreases seizures in a mouse model of Tuberous Sclerosis Complex

(2010) Ling-Hui Zeng et al.   NEUROBIOLOGY OF DISEASE

Vagus Nerve Stimulation for Refractory Epilepsy in Tuberous Sclerosis

(2010) Nelia Zamponi et al.   PEDIATRIC NEUROLOGY

New Drugs for Pediatric Epilepsy

(2010) Catherine J. Chu-Shore et al.   Seminars in Pediatric Neurology

The tuberous sclerosis complex

(2009) Ksenia A. Orlova et al.   Annals of the New York Academy of Sciences

Gene Expression Analysis of Tuberous Sclerosis Complex Cortical Tubers Reveals Increased Expression of Adhesion and Inflammatory Factors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Pi3K-mTOR Signaling and AMOG Expression in Epilepsy-associated Glioneuronal Tumors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Progressive multifocal cystlike cortical tubers in tuberous sclerosis complex: Clinical and neuropathologic findings

(2009) Catherine J. Chu-Shore et al.   EPILEPSIA

Doublecortin-like (DCL) expression in focal cortical dysplasia and cortical tubers

(2009) Karin Boer et al.   EPILEPSIA

Animal models of focal cortical dysplasia and tuberous sclerosis complex: Recent progress toward clinical applications

(2009) Michael Wong   EPILEPSIA

Focal brain malformations: Seizures, signaling, sequencing

(2009) Peter B. Crino   EPILEPSIA

Early control of seizures improves long-term outcome in children with tuberous sclerosis complex

(2009) Roberta Bombardieri et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

(2009) Bin Zheng et al.   MOLECULAR CELL

Epileptogenesis in the immature brain: emerging mechanisms

(2009) Sanjay N. Rakhade et al.   Nature Reviews Neurology

Cyst-like tubers are associated with TSC2 and epilepsy in tuberous sclerosis complex

(2009) C. J. Chu-Shore et al.   NEUROLOGY

Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E

(2009) Rosaura Esteve-Puig et al.   PLoS One

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

Rapamycin and tuberous sclerosis complex: From Easter Island to epilepsy

(2008) Peter B. Crino   ANNALS OF NEUROLOGY

Cell-specific alterations of glutamate receptor expression in tuberous sclerosis complex cortical tubers

(2008) Delia M. Talos et al.   ANNALS OF NEUROLOGY

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex

(2008) Ling-Hui Zeng et al.   ANNALS OF NEUROLOGY

Molecular and cellular basis of epileptogenesis in symptomatic epilepsy

(2008) Asla Pitkänen et al.   EPILEPSY & BEHAVIOR

Response of a Neuronal Model of Tuberous Sclerosis to Mammalian Target of Rapamycin (mTOR) Inhibitors: Effects on mTORC1 and Akt Signaling Lead to Improved Survival and Function

(2008) L. Meikle et al.   JOURNAL OF NEUROSCIENCE

Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2008) K. Boer et al.   NEUROSCIENCE

Epilepsy surgery and tuberous sclerosis complex: special considerations

(2008) Robert J. Bollo et al.   Neurosurgical Focus

Mechanisms of Epileptogenesis in Tuberous Sclerosis Complex and Related Malformations of Cortical Development with Abnormal Glioneuronal Proliferation

(2007) Michael Wong   EPILEPSIA

Defining the spectrum of international practice in pediatric epilepsy surgery patients

(2007) A. Simon Harvey et al.   EPILEPSIA

Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2007) K. Boer et al.   EPILEPSY RESEARCH

Prenatal diagnosis of cerebral lesions in Tuberous sclerosis complex (TSC). Case report and review of the literature

(2007) S.B. Wortmann et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY