Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment

Searching for convergent pathways in autism spectrum disorders: insights from human brain transcriptome studies

(2016) Akira Gokoolparsadh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Role of mTOR Inhibitors in the Treatment of Patients with Tuberous Sclerosis Complex: Evidence-based and Expert Opinions

(2016) Paolo Curatolo et al.   DRUGS

MicroRNA‐34/449 controls mitotic spindle orientation during mammalian cortex development

(2016) Juan Pablo Fededa et al.   EMBO JOURNAL

Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures

(2016) J. van Scheppingen et al.   GLIA

Adjunctive everolimus therapy for treatment-resistant focal-onset seizures associated with tuberous sclerosis (EXIST-3): a phase 3, randomised, double-blind, placebo-controlled study

(2016) Jacqueline A French et al.   LANCET

Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference

(2016) Mustafa Sahin et al.   PEDIATRIC NEUROLOGY

Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing

(2016) Marina Falaleeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Principles of miRNA–mRNA interactions: beyond sequence complementarity

(2015) Fabian Afonso-Grunz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Validated MicroRNA Target Databases: An Evaluation

(2015) Yun Ji Diana Lee et al.   DRUG DEVELOPMENT RESEARCH

Differential expression and clinical significance of three inflammation-related microRNAs in gangliogliomas

(2015) A. S. Prabowo et al.   Journal of Neuroinflammation

Neurological and neuropsychiatric aspects of tuberous sclerosis complex

(2015) Paolo Curatolo et al.   LANCET NEUROLOGY

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(2015) Brendon Scicluna et al.   MOLECULAR MEDICINE

Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders

(2015) Neelroop N. Parikshak et al.   NATURE REVIEWS GENETICS

Inflammatory mechanisms contribute to the neurological manifestations of tuberous sclerosis complex

(2015) Bo Zhang et al.   NEUROBIOLOGY OF DISEASE

A survey of human brain transcriptome diversity at the single cell level

(2015) Spyros Darmanis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intersection of mTOR and STAT signaling in immunity

(2015) Diana Saleiro et al.   TRENDS IN IMMUNOLOGY

Immunity and Inflammation in Epilepsy

(2015) Annamaria Vezzani et al.   Cold Spring Harbor Perspectives in Medicine

Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders

(2015) Bradley P. Ander et al.   Molecular Autism

miR-34: from bench to bedside

(2015) Massimiliano Agostini et al.   Oncotarget

Functions and Dysfunctions of Adult Hippocampal Neurogenesis

(2014) Kimberly M. Christian et al.   Annual Review of Neuroscience

The many faces of small nucleolar RNAs

(2014) Tomaž Bratkovič et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Cortical Tubers: Windows into Dysregulation of Epilepsy Risk and Synaptic Signaling Genes by MicroRNAs

(2014) Alan A. Dombkowski et al.   CEREBRAL CORTEX

MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins

(2014) Ana L. Morgado et al.   MOLECULAR NEUROBIOLOGY

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation

(2014) Lior Mayo et al.   NATURE MEDICINE

Unique Behavioral Characteristics and microRNA Signatures in a Drug Resistant Epilepsy Model

(2014) Jangsup Moon et al.   PLoS One

Differential regulation of non-protein coding RNAs from Prader-Willi Syndrome locus

(2014) Chenna R. Galiveti et al.   Scientific Reports

Triggering receptor expressed on myeloid cells-1 (TREM-1): a new player in antiviral immunity?

(2014) Kelsey Roe et al.   Frontiers in Microbiology

Bioinformatics analysis of protein interaction networks: Statistics, topologies, and meeting the standards of experimental biologists

(2013) V. P. Bulgakov et al.   BIOCHEMISTRY-MOSCOW

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

RCytoscape: tools for exploratory network analysis

(2013) Paul T Shannon et al.   BMC BIOINFORMATICS

Supervised, semi-supervised and unsupervised inference of gene regulatory networks

(2013) S. R. Maetschke et al.   BRIEFINGS IN BIOINFORMATICS

Beyond microRNA – Novel RNAs derived from small non-coding RNA and their implication in cancer

(2013) Elena S. Martens-Uzunova et al.   CANCER LETTERS

Small nucleolar RNAs and RNA-guided post-transcriptional modification

(2013) Lauren Lui et al.   Essays in Biochemistry

Emerging roles for triggering receptor expressed on myeloid cells receptor family signaling in inflammatory diseases

(2013) Christopher J Pelham et al.   Expert Review of Clinical Immunology

High-throughput sequencing for biology and medicine

(2013) W. W. Soon et al.   Molecular Systems Biology

MicroRNA-34a regulates cardiac ageing and function

(2013) Reinier A. Boon et al.   NATURE

Tuberous Sclerosis Complex Diagnostic Criteria Update: Recommendations of the 2012 International Tuberous Sclerosis Complex Consensus Conference

(2013) Hope Northrup et al.   PEDIATRIC NEUROLOGY

Novel small Cajal-body-specific RNAs identified in Drosophila: probing guide RNA function

(2013) S. Deryusheva et al.   RNA

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Comparison of co-expression measures: mutual information, correlation, and model based indices

(2012) Lin Song et al.   BMC BIOINFORMATICS

Fetal Brain Lesions in Tuberous Sclerosis Complex: TORC1 Activation and Inflammation

(2012) Avanita S. Prabowo et al.   BRAIN PATHOLOGY

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Astrocyte immune responses in epilepsy

(2012) Eleonora Aronica et al.   GLIA

Microglia and neurodegeneration: The role of systemic inflammation

(2012) Colm Cunningham   GLIA

miRNA-34c regulates Notch signaling during bone development

(2012) Yangjin Bae et al.   HUMAN MOLECULAR GENETICS

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

The role of inflammation in epileptogenesis

(2012) Annamaria Vezzani et al.   NEUROPHARMACOLOGY

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depression and Hippocampal Neurogenesis: A Road to Remission?

(2012) A. J. Eisch et al.   SCIENCE

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

TOR in the immune system

(2011) Koichi Araki et al.   CURRENT OPINION IN CELL BIOLOGY

Epilepsy and brain inflammation

(2011) Annamaria Vezzani et al.   EXPERIMENTAL NEUROLOGY

The central role of RNA in human development and cognition

(2011) John S. Mattick   FEBS LETTERS

Functional assessment of variants in the TSC1 and TSC2 genes identified in individuals with Tuberous Sclerosis Complex

(2011) Marianne Hoogeveen-Westerveld et al.   HUMAN MUTATION

microRNA-34 family and treatment of cancers with mutant or wild-type p53 (Review)

(2011) Yang   INTERNATIONAL JOURNAL OF ONCOLOGY

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

miR-34a Regulates Mouse Neural Stem Cell Differentiation

(2011) Márcia M. Aranha et al.   PLoS One

MiR-34a Targeting of Notch Ligand Delta-Like 1 Impairs CD15+/CD133+ Tumor-Propagating Cells and Supports Neural Differentiation in Medulloblastoma

(2011) Pasqualino de Antonellis et al.   PLoS One

Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets

(2011) M. Agostini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-34a regulates neurite outgrowth, spinal morphology, and function

(2011) M. Agostini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p53 and MicroRNA-34 Are Suppressors of Canonical Wnt Signaling

(2011) N. H. Kim et al.   Science Signaling

MicroRNA-Driven Developmental Remodeling in the Brain Distinguishes Humans from Other Primates

(2011) Mehmet Somel et al.   PLOS BIOLOGY

Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation

(2010) Márcia M Aranha et al.   BMC GENOMICS

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

(2010) Carolina Tarantino et al.   FASEB JOURNAL

Weighted Gene Coexpression Network Analysis: State of the Art

(2010) Wei Zhao et al.   Journal of Biopharmaceutical Statistics

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Gene Expression Analysis of Tuberous Sclerosis Complex Cortical Tubers Reveals Increased Expression of Adhesion and Inflammatory Factors

(2009) Karin Boer et al.   BRAIN PATHOLOGY

Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data

(2009) J. M. Ruijter et al.   NUCLEIC ACIDS RESEARCH

Tuberous sclerosis

(2008) Paolo Curatolo et al.   LANCET

Epilepsy surgery and tuberous sclerosis complex: special considerations

(2008) Robert J. Bollo et al.   Neurosurgical Focus

Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex

(2007) K. Boer et al.   EPILEPSY RESEARCH

Gene expression profile analysis of epilepsy-associated gangliogliomas

(2007) E. Aronica et al.   NEUROSCIENCE