标题
The Oxytocin Receptor: From Intracellular Signaling to Behavior
作者
关键词
-
出版物
PHYSIOLOGICAL REVIEWS
Volume 98, Issue 3, Pages 1805-1908
出版商
American Physiological Society
发表日期
2018-06-14
DOI
10.1152/physrev.00031.2017
参考文献
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- Oxytocin stimulates adult neurogenesis even under conditions of stress and elevated glucocorticoids
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- Oxytocin in the medial preoptic area facilitates male sexual behavior in the rat
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- Somatic genital reflexes in rats with a nod to humans: Anatomy, physiology, and the role of the social neuropeptides
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- CD38 and its role in oxytocin secretion and social behavior
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- The role of oxytocin in mating and pregnancy
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- Both oxytocin and vasopressin are mediators of maternal care and aggression in rodents: From central release to sites of action
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- Breaking the loop: Oxytocin as a potential treatment for drug addiction
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- Somatodendritic Dopamine Release Requires Synaptotagmin 4 and 7 and the Participation of Voltage-gated Calcium Channels
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- Mitogen-activated Protein Kinase Kinase 1 (MEK1) Stabilizes MyoD through Direct Phosphorylation at Tyrosine 156 During Myogenic Differentiation
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- Functional Selective Oxytocin-derived Agonists Discriminate between Individual G Protein Family Subtypes
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- Oxytocin suppresses basal glutamatergic transmission but facilitates activity-dependent synaptic potentiation in the medial prefrontal cortex
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- Changes in the Intensity of Maternal Aggression and Central Oxytocin and Vasopressin V1a Receptors Across the Peripartum Period in the Rat
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- Oxytocin Revisited: Its Role in Cardiovascular Regulation
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- Modulation of anxiety behavior in the elevated plus maze using peptidic oxytocin and vasopressin receptor ligands in the rat
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- Anxiolytic-like effect of oxytocin in the simulated public speaking test
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- Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
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- SIK2 Is a Key Regulator for Neuronal Survival after Ischemia via TORC1-CREB
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- The Neuropeptide Oxytocin Facilitates Pro-Social Behavior and Prevents Social Avoidance in Rats and Mice
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- Early life stress disrupts peripubertal development of aggression in male mice
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- Effects of chronic social defeat on behavioral and neural correlates of sociality: Vasopressin, oxytocin and the vasopressinergic V1b receptor
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- Oxytocin, vasopressin and estrogen receptor gene expression in relation to social recognition in female mice
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- Mechanisms of the Anti-Obesity Effects of Oxytocin in Diet-Induced Obese Rats
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- Yes, I Am Ready Now: Differential Effects of Paced versus Unpaced Mating on Anxiety and Central Oxytocin Release in Female Rats
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- The Involvement of Voltage-Operated Calcium Channels in Somato-Dendritic Oxytocin Release
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- Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans
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- Dendritic SNAREs add a new twist to the old neuron theory
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- Thin-slicing study of the oxytocin receptor (OXTR) gene and the evaluation and expression of the prosocial disposition
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- Oxytocin modulates selection of allies in intergroup conflict
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- The influence of depressive symptomatology and perceived stress on plasma and salivary oxytocin before, during and after a support enhancement intervention
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- Neuroanatomical evidence for reciprocal regulation of the corticotrophin-releasing factor and oxytocin systems in the hypothalamus and the bed nucleus of the stria terminalis of the rat: Implications for balancing stress and affect
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- Oxytocin buffers cortisol responses to stress in individuals with impaired emotion regulation abilities
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- Low CSF oxytocin reflects high intent in suicide attempters
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- Effects of intranasal oxytocin on social anxiety in males with fragile X syndrome
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- Evaluation of Enzyme Immunoassay and Radioimmunoassay Methods for the Measurement of Plasma Oxytocin
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- Functional Implications of Glutamatergic Projections to the Ventral Tegmental Area
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- Oxytocin Selectively Gates Fear Responses Through Distinct Outputs from the Central Amygdala
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- Working Without Kinase Activity: Phosphotransfer-Independent Functions of Extracellular Signal-Regulated Kinases
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- Neural correlates of long-term intense romantic love
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- β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration
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- Serotonin impairs copulation and attenuates ejaculation-induced glutamate activity in the medial preoptic area.
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- Adjunctive Intranasal Oxytocin Reduces Symptoms in Schizophrenia Patients
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- Oxytocin and the Development of Parenting in Humans
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- Labor and Inflammation Increase the Expression of Oxytocin Receptor in Human Amnion1
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- Subchronic treatment of rats with oxytocin results in improved adipocyte differentiation and increased gene expression of factors involved in adipogenesis
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- Arrestins differentially regulate histamine- and oxytocin-evoked phospholipase C and mitogen-activated protein kinase signalling in myometrial cells
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- REVIEW: Oxytocin: Crossing the Bridge between Basic Science and Pharmacotherapy
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- Dopamine and Oxytocin Interactions Underlying Behaviors: Potential Contributions to Behavioral Disorders
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- Strong and Consistent Social Bonds Enhance the Longevity of Female Baboons
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- Social Bonds Enhance Reproductive Success in Male Macaques
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- An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments
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- Epidermal Growth Factor Receptor Is an Obligatory Intermediate for Oxytocin-Induced Cyclooxygenase 2 Expression and Prostaglandin F2αProduction in Bovine Endometrial Epithelial Cells
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- Involvement of Transducer of Regulated cAMP Response Element-Binding Protein Activity on Corticotropin Releasing Hormone Transcription
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- Oxytocin-Dopamine Interactions Mediate Variations in Maternal Behavior in the Rat
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- Vasopressin released within the central amygdala promotes maternal aggression
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- Regulation of the hypothalamic Thyrotropin Releasing Hormone (TRH) neuron by neuronal and peripheral inputs
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- Sex differences in hormonal responses to social conflict in the monogamous California mouse
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- Distinct correlations of vasopressin release within the lateral septum and the bed nucleus of the stria terminalis with the display of intermale aggression
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- Regulation of Dendritic Development by BDNF Requires Activation of CRTC1 by Glutamate
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- Ovarian hormone-induced reorganization of oxytocin-labeled dendrites and synapses lateral to the hypothalamic ventromedial nucleus in female rats
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- A novel MEK2/PI3Kδ pathway controls the expression of IL-1 receptor antagonist in IFN-β-activated human monocytes
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- Bridging the Gap between GPCR Activation and Behaviour: Oxytocin and Prolactin Signalling in the Hypothalamus
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- Effects of Cholecystokinin in the Supraoptic Nucleus and Paraventricular Nucleus are Negatively Modulated by Leptin in 24-h Fasted Lean Male Rats
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- Maternal Behaviour is Associated with Vasopressin Release in the Medial Preoptic Area and Bed Nucleus of the Stria Terminalis in the Rat
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- Stress Induces Parallel Changes in Corticotrophin-Releasing Hormone (CRH) Transcription and Nuclear Translocation of Transducer of Regulated cAMP Response Element-Binding Activity 2 in Hypothalamic CRH Neurones
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- Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans
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- Erasing Fear Memories with Extinction Training
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- The Fat-Induced Satiety Factor Oleoylethanolamide Suppresses Feeding through Central Release of Oxytocin
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- Oxytocin Induces the Migration of Prostate Cancer Cells: Involvement of the Gi-Coupled Signaling Pathway
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- Optogenetics
- (2010) Karl Deisseroth NATURE METHODS
- Combined administration of secretin and oxytocin inhibits chronic colitis and associated activation of forebrain neurons
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- Oxytocin Attenuates Amygdala Reactivity to Fear in Generalized Social Anxiety Disorder
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- Oxytocin receptor (OXTR) does not play a major role in the aetiology of autism: Genetic and molecular studies
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- Oxytocin Signaling in Mouse Taste Buds
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- Viewing Pictures of a Romantic Partner Reduces Experimental Pain: Involvement of Neural Reward Systems
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- Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking
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- miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor
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- A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function
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- Experimental peripheral administration of oxytocin elevates a suite of cooperative behaviours in a wild social mammal
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- Oxytocin receptor gene polymorphism (rs2254298) interacts with familial risk for psychopathology to predict symptoms of depression and anxiety in adolescent girls
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- Assessing the antidepressant-like effects of carbetocin, an oxytocin agonist, using a modification of the forced swimming test
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- Angiotensin IV elevates oxytocin levels in the rat amygdala and produces anxiolytic-like activity through subsequent oxytocin receptor activation
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- Oxytocin improves specific recognition of positive facial expressions
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- The Neuropeptide Oxytocin Regulates Parochial Altruism in Intergroup Conflict Among Humans
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- Maternal cortisol in late pregnancy and hypothalamic–pituitary–adrenal reactivity to psychosocial stress postpartum in women
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- Aggression and anxiety: social context and neurobiological links
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- The effect of barusiban, a selective oxytocin antagonist, in threatened preterm labor at late gestational age: a randomized, double-blind, placebo-controlled trial
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- Intracellular trafficking of the human oxytocin receptor: evidence of receptor recycling via a Rab4/Rab5 “short cycle”
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- Defensive Behavioral Strategies and Enhanced State Anxiety during Chronic Subordinate Colony Housing Are Accompanied by Reduced Hypothalamic Vasopressin, But Not Oxytocin, Expression
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- Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors
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- Deletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities
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- Leptin modulates noradrenaline release in the paraventricular nucleus and plasma oxytocin levels in female rats: A microdialysis study
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- Reduction in TRPC4 expression specifically attenuates G-protein coupled receptor-stimulated increases in intracellular calcium in human myometrial cells
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- Heterotrimeric G proteins demonstrate differential sensitivity to β-arrestin dependent desensitization
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- Mothers' concentrations of oxytocin following close, physical interactions with biological and nonbiological children
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- Regulatory Mechanisms Underlying Corticotropin-Releasing Factor Gene Expression in the Hypothalam
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- Attenuation of Canonical Transient Receptor Potential-Like Channel 6 Expression Specifically Reduces the Diacylglycerol-Mediated Increase in Intracellular Calcium in Human Myometrial Cells
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- Oxytocin Increases Glucose Uptake in Neonatal Rat Cardiomyocytes
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- Dopamineâoxytocin interactions in penile erection
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- Oxytocin injected into the ventral subiculum or the posteromedial cortical nucleus of the amygdala induces penile erection and increases extracellular dopamine levels in the nucleus accumbens of male rats
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- Plasma Levels of Oxytocin and Vasopressin before, during and after Parturition in Cows
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- Plasma Oxytocin Concentrations in Man after Different Routes of Administration of Synthetic Oxytocin
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- The advantage of social living: Brain neuropeptides mediate the beneficial consequences of sex and motherhood
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- Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior
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- Attenuation of the neuronal stress responsiveness and corticotrophin releasing hormone synthesis after sexual activity in male rats
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- Manipulation of the oxytocin system alters social behavior and attraction in pair-bonding primates, Callithrix penicillata
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- Central vasopressin and oxytocin receptor distributions in two species of singing mice
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- Central and Peripheral Effects of Thyroid Hormone Signalling in the Control of Energy Metabolism
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- Immune allergic response in Asperger syndrome
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- Oxytocin Makes a Face in Memory Familiar
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- Evidence That Oxytocin Exerts Anxiolytic Effects via Oxytocin Receptor Expressed in Serotonergic Neurons in Mice
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- Variation in Oxytocin Receptor Density in the Nucleus Accumbens Has Differential Effects on Affiliative Behaviors in Monogamous and Polygamous Voles
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- Intranasal delivery to the central nervous system: Mechanisms and experimental considerations
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- REVIEWS: Pathways of Sexual Desire
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- Antinociceptive Action of Oxytocin Involves Inhibition of Potassium Channel Currents in Lamina Ii Neurons of the Rat Spinal Cord
- (2009) Jean Didier Breton et al. Molecular Pain
- Synaptotagmin IV: a multifunctional regulator of peptidergic nerve terminals
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- Effects of Chronic Intracerebral Prolactin on the Oxytocinergic and Vasopressinergic System of Virgin Ovariectomized Rats
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- Effects of oxytocin on methamphetamine-induced conditioned place preference and the possible role of glutamatergic neurotransmission in the medial prefrontal cortex of mice in reinstatement
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- Chronic icv oxytocin attenuates the pathological high anxiety state of selectively bred Wistar rats
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- Oxytocin-induced elevation of ADP-ribosyl cyclase activity, cyclic ADP-riboseor Ca2+ concentrations is involved in autoregulation of oxytocin secretionin the hypothalamus and posterior pituitary in male mice
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- Oxytocin enhances the inhibitory effects of diazepam in the rat central medial amygdala
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- Maternal separation interferes with developmental changes in brain vasopressin and oxytocin receptor binding in male rats
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- Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats
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- Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
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- Characterization of the oxytocin system regulating affiliative behavior in female prairie voles
- (2009) H.E. Ross et al. NEUROSCIENCE
- Oxytocin response to an experimental psychosocial challenge in adults exposed to traumatic experiences during childhood or adolescence
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- Regulation of somatodendritic dopamine release by corticotropin-releasing factor via the inhibition of voltage-operated Ca2+ channels
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- Distribution of vasopressin and oxytocin binding sites in the brain and upper spinal cord of the common marmoset
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- The Oxytocin Receptor (OXTR) Contributes to Prosocial Fund Allocations in the Dictator Game and the Social Value Orientations Task
- (2009) Salomon Israel et al. PLoS One
- Social bonds between unrelated females increase reproductive success in feral horses
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- Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans
- (2009) Sarina M. Rodrigues et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Serum oxytocin levels in patients with depression and the effects of gender and antidepressant treatment
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- Oxytocin receptor polymorphisms and adult attachment style in patients with depression
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- Cerebrospinal fluid oxytocin, life history of aggression, and personality disorder
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- A randomized controlled trial of intranasal oxytocin as an adjunct to exposure therapy for social anxiety disorder
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- Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation
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- Effects of intranasal oxytocin on emotional face processing in women
- (2009) Gregor Domes et al. PSYCHONEUROENDOCRINOLOGY
- Oxytocin, vasopressin, prostaglandin F2α, luteinizing hormone, testosterone, estrone sulfate, and cortisol plasma concentrations after sexual stimulation in stallions
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- Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System
- (2008) Steven W. Flavell et al. Annual Review of Neuroscience
- Intranasal Oxytocin Increases Positive Communication and Reduces Cortisol Levels During Couple Conflict
- (2008) Beate Ditzen et al. BIOLOGICAL PSYCHIATRY
- Multiple Signals Regulate Phospholipase CBeta3 in Human Myometrial Cells1
- (2008) Miao Zhong et al. BIOLOGY OF REPRODUCTION
- Brain oxytocin receptors mediate ejaculation elicited by 7-hydroxy-2-(di-N-propylamino) tetralin (7-OH-DPAT) in anaesthetized rats
- (2008) P Clément et al. BRITISH JOURNAL OF PHARMACOLOGY
- From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long-term adverse consequences of drug use?
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- A Conditional Knockout Mouse Line of the Oxytocin Receptor
- (2008) Heon-Jin Lee et al. ENDOCRINOLOGY
- Acute changes in endocrine and fluid balance markers during high-intensity, steady-state, and prolonged endurance running: unexpected increases in oxytocin and brain natriuretic peptide during exercise
- (2008) Tamara Hew-Butler et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Oxytocin reduces anxiety via ERK1/2 activation: local effect within the rat hypothalamic paraventricular nucleus
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- The vasopressin system — From antidiuresis to psychopathology
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- Involvement of septal Cdk5 in the emergence of excessive anxiety induced by stress
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- The paraventricular nucleus of the hypothalamus – a potential target for integrative treatment of autonomic dysfunction
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- Sexual behavior modulates contextual fear memory through dopamine D1/D5 receptors
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- Dog's gaze at its owner increases owner's urinary oxytocin during social interaction
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- Oxytocin Attenuates Affective Evaluations of Conditioned Faces and Amygdala Activity
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- Neurotransmitters and peptides: whispered secrets and public announcements
- (2008) Gareth Leng et al. JOURNAL OF PHYSIOLOGY-LONDON
- Oxytocin enhances processing of positive versus negative emotional information in healthy male volunteers
- (2008) M Di Simplicio et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Oxytocin Deficiency Mediates Hyperphagic Obesity ofSim1Haploinsufficient Mice
- (2008) Bassil M. Kublaoui et al. MOLECULAR ENDOCRINOLOGY
- Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances
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- Control of the establishment of aversive memory by calcineurin and Zif268
- (2008) Karsten Baumgärtel et al. NATURE NEUROSCIENCE
- Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection
- (2008) Steven W. Flavell et al. NEURON
- The CRF System Mediates Increased Passive Stress-Coping Behavior Following the Loss of a Bonded Partner in a Monogamous Rodent
- (2008) Oliver J Bosch et al. NEUROPSYCHOPHARMACOLOGY
- Oxytocin receptor-deficient mice developed late-onset obesity
- (2008) Yuki Takayanagi et al. NEUROREPORT
- Neuroendocrine control of food intake
- (2008) Elena Valassi et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- Brain vasopressin is an important regulator of maternal behavior independent of dams' trait anxiety
- (2008) O. J. Bosch et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Post-learning intranasal oxytocin modulates human memory for facial identity
- (2008) Egemen Savaskan et al. PSYCHONEUROENDOCRINOLOGY
- The acute effects of intranasal oxytocin administration on endocrine and sexual function in males
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- Does oxytocin influence the early detection of angry and happy faces?
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