Nucleic acids: function and potential for abiogenesis

High-Throughput Mutational Analysis of a Twister Ribozyme

(2016) Shungo Kobori et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Group II Intron Self-Splicing

(2016) Anna Marie Pyle   Annual Review of Biophysics

DNA Oligonucleotide 3′-Phosphorylation by a DNA Enzyme

(2016) Alison J. Camden et al.   BIOCHEMISTRY

Two Active Site Divalent Ions in the Crystal Structure of the Hammerhead Ribozyme Bound to a Transition State Analogue

(2016) Aamir Mir et al.   BIOCHEMISTRY

Passive Noise Filtering by Cellular Compartmentalization

(2016) Thomas Stoeger et al.   CELL

Nanostructures from Synthetic Genetic Polymers

(2016) Alexander I. Taylor et al.   CHEMBIOCHEM

Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying

(2016) Noam Prywes et al.   CHEMICAL COMMUNICATIONS

CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast

(2016) Thi Hoang Duong Nguyen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Whither Ribosome Structure and Dynamics Research? (A Perspective)

(2016) Joachim Frank   JOURNAL OF MOLECULAR BIOLOGY

The Novel Chemical Mechanism of the Twister Ribozyme

(2016) Timothy J. Wilson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribozyme Catalysis with a Twist: Active State of the Twister Ribozyme in Solution Predicted from Molecular Simulation

(2016) Colin S. Gaines et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Catalyzed Amide Hydrolysis

(2016) Cong Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Highly Reactive Imidazolium-Bridged Dinucleotide Intermediate in Nonenzymatic RNA Primer Extension

(2016) Travis Walton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of a DNA catalyst

(2016) Almudena Ponce-Salvatierra et al.   NATURE

Oligoarginine peptides slow strand annealing and assist non-enzymatic RNA replication

(2016) Tony Z. Jia et al.   Nature Chemistry

The effect of leaving groups on binding and reactivity in enzyme-free copying of DNA and RNA

(2016) Eric Kervio et al.   NUCLEIC ACIDS RESEARCH

Amplification of RNA by an RNA polymerase ribozyme

(2016) David P. Horning et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A high-yielding, strictly regioselective prebiotic purine nucleoside formation pathway

(2016) S. Becker et al.   SCIENCE

From the RNA world to the clinic

(2016) B. A. Sullenger et al.   SCIENCE

Beyond prebiotic chemistry

(2016) Leroy Cronin et al.   SCIENCE

The 3.8 A structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis

(2016) R. Wan et al.   SCIENCE

Catalytic DNA: Scope, Applications, and Biochemistry of Deoxyribozymes

(2016) Scott K. Silverman   TRENDS IN BIOCHEMICAL SCIENCES

Spontaneous formation and base pairing of plausible prebiotic nucleotides in water

(2016) Brian J. Cafferty et al.   Nature Communications

Ribozymes and the mechanisms that underlie RNA catalysis

(2016) Timothy J. Wilson et al.   Frontiers of Chemical Science and Engineering

Pursuing DNA Catalysts for Protein Modification

(2015) Scott K. Silverman   ACCOUNTS OF CHEMICAL RESEARCH

Spontaneous Formation of RNA Strands, Peptidyl RNA, and Cofactors

(2015) Mario Jauker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrostatic Localization of RNA to Protocell Membranes by Cationic Hydrophobic Peptides

(2015) Neha P. Kamat et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class

(2015) Marija Košutić et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Origin of Life-Out of the Blue

(2015) John D. Sutherland   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′-5′ Linkages

(2015) Christopher Cozens et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Engineering of ribozymes with useful activities in the ancient RNA world

(2015) Sabine Müller   Annals of the New York Academy of Sciences

Lanthanide-dependent RNA-cleaving DNAzymes as metal biosensors

(2015) Juewen Liu   CANADIAN JOURNAL OF CHEMISTRY

The RNA World as a Model System to Study the Origin of Life

(2015) Abe Pressman et al.   CURRENT BIOLOGY

Minimal Hammerhead Ribozymes with Uncompromised Catalytic Activity

(2015) Sara M. O'Rourke et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of the Same Na+-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions

(2015) Seyed-Fakhreddin Torabi et al.   JOURNAL OF MOLECULAR EVOLUTION

Structural Basis for a Six Nucleotide Genetic Alphabet

(2015) Millie M. Georgiadis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Replacing Uridine with 2-Thiouridine Enhances the Rate and Fidelity of Nonenzymatic RNA Primer Extension

(2015) Benjamin D. Heuberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity

(2015) Eva Nogales et al.   MOLECULAR CELL

DNA Catalysis: The Chemical Repertoire of DNAzymes

(2015) Marcel Hollenstein   MOLECULES

The architecture of the spliceosomal U4/U6.U5 tri-snRNP

(2015) Thi Hoang Duong Nguyen et al.   NATURE

Crystal structure of the Varkud satellite ribozyme

(2015) Nikolai B Suslov et al.   Nature Chemical Biology

New classes of self-cleaving ribozymes revealed by comparative genomics analysis

(2015) Zasha Weinberg et al.   Nature Chemical Biology

How do metal ions direct ribozyme folding?

(2015) Natalia A. Denesyuk et al.   Nature Chemistry

Freeze–thaw cycles as drivers of complex ribozyme assembly

(2015) Hannes Mutschler et al.   Nature Chemistry

Heat flux across an open pore enables the continuous replication and selection of oligonucleotides towards increasing length

(2015) Moritz Kreysing et al.   Nature Chemistry

Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

(2015) Bhavesh H. Patel et al.   Nature Chemistry

DNA nanotechnology from the test tube to the cell

(2015) Yuan-Jyue Chen et al.   Nature Nanotechnology

The structural diversity of artificial genetic polymers

(2015) Irina Anosova et al.   NUCLEIC ACIDS RESEARCH

A DNAzyme requiring two different metal ions at two distinct sites

(2015) Wenhu Zhou et al.   NUCLEIC ACIDS RESEARCH

In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing

(2015) Seyed-Fakhreddin Torabi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical analysis of pistol self-cleaving ribozymes

(2015) Kimberly A. Harris et al.   RNA

Biochemical analysis of hatchet self-cleaving ribozymes

(2015) Sanshu Li et al.   RNA

Structure of a yeast spliceosome at 3.6-angstrom resolution

(2015) Chuangye Yan et al.   SCIENCE

Chemistry and Biology of Self-Cleaving Ribozymes

(2015) Randi M. Jimenez et al.   TRENDS IN BIOCHEMICAL SCIENCES

RNA Self-Assembly and RNA Nanotechnology

(2014) Wade W. Grabow et al.   ACCOUNTS OF CHEMICAL RESEARCH

In Vitro Selection of a New Lanthanide-Dependent DNAzyme for Ratiometric Sensing Lanthanides

(2014) Po-Jung Jimmy Huang et al.   ANALYTICAL CHEMISTRY

DNA-Catalyzed Lysine Side Chain Modification

(2014) Benjamin M. Brandsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Hierarchy of RNA Functional Dynamics

(2014) Anthony M. Mustoe et al.   Annual Review of Biochemistry

Understanding Nucleic Acid–Ion Interactions

(2014) Jan Lipfert et al.   Annual Review of Biochemistry

Themes and variations in riboswitch structure and function

(2014) Alla Peselis et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones

(2014) Thomas R. Cech et al.   CELL

Aptamers and SELEX in Chemistry & Biology

(2014) Michael Famulok et al.   CHEMISTRY & BIOLOGY

Highly Efficient Self-Replicating RNA Enzymes

(2014) Michael P. Robertson et al.   CHEMISTRY & BIOLOGY

Limits of Neutral Drift: Lessons From the In Vitro Evolution of Two Ribozymes

(2014) Katherine L. Petrie et al.   JOURNAL OF MOLECULAR EVOLUTION

Generation of Oligonucleotides Under Hydrothermal Conditions by Non-enzymatic Polymerization

(2014) Veronica DeGuzman et al.   JOURNAL OF MOLECULAR EVOLUTION

Structural DNA Nanotechnology: State of the Art and Future Perspective

(2014) Fei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Free Energy Landscape of Pseudorotation in 3′–5′ and 2′–5′ Linked Nucleic Acids

(2014) Li Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A semi-synthetic organism with an expanded genetic alphabet

(2014) Denis A. Malyshev et al.   NATURE

A cross-chiral RNA polymerase ribozyme

(2014) Jonathan T. Sczepanski et al.   NATURE

Crystal structure and mechanistic investigation of the twister ribozyme

(2014) Yijin Liu et al.   Nature Chemical Biology

A synthetic approach to abiogenesis

(2014) James Attwater et al.   NATURE METHODS

A ribozyme that triphosphorylates RNA 5′-hydroxyl groups

(2014) Janina E. Moretti et al.   NUCLEIC ACIDS RESEARCH

Structural insights into the effects of 2'-5' linkages on the RNA duplex

(2014) J. Sheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for the fast self-cleavage reaction catalyzed by the twister ribozyme

(2014) D. Eiler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards XNA nanotechnology: new materials from synthetic genetic polymers

(2014) Vitor B. Pinheiro et al.   TRENDS IN BIOTECHNOLOGY

Evolution of oil droplets in a chemorobotic platform

(2014) Juan Manuel Parrilla Gutierrez et al.   Nature Communications

In-line alignment and Mg2+ coordination at the cleavage site of the env22 twister ribozyme

(2014) Aiming Ren et al.   Nature Communications

Phosphorothioates, Essential Components of Therapeutic Oligonucleotides

(2014) Fritz Eckstein   Nucleic Acid Therapeutics

Artificial Genetic Sets Composed of Size-Expanded Base Pairs

(2013) Malte Winnacker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanisms of Autocatalysis

(2013) Andrew J. Bissette et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural Basis of the Translational Elongation Cycle

(2013) Rebecca M. Voorhees et al.   Annual Review of Biochemistry

Structural Studies of RNase P

(2013) Alfonso Mondragón   Annual Review of Biophysics

The “Strong” RNA World Hypothesis: Fifty Years Old

(2013) Marc Neveu et al.   ASTROBIOLOGY

The Next-Generation Sequencing Revolution and Its Impact on Genomics

(2013) Daniel C. Koboldt et al.   CELL

A Decade of Riboswitches

(2013) Alexander Serganov et al.   CELL

The Origin of RNA and “My Grandfather’s Axe”

(2013) Nicholas V. Hud et al.   CHEMISTRY & BIOLOGY

Lanthanide Cofactors Accelerate DNA-Catalyzed Synthesis of Branched RNA

(2013) Fatemeh Javadi-Zarnaghi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Simple Fluorescence Method for pKa Determination in RNA and DNA Reveals Highly Shifted pKa’s

(2013) Jennifer L. Wilcox et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Catalyzed Hydrolysis of Esters and Aromatic Amides

(2013) Benjamin M. Brandsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic DNAs That Harness Violet Light To Repair Thymine Dimers in a DNA Substrate

(2013) Adam Barlev et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small, Highly Active DNAs That Hydrolyze DNA

(2013) Hongzhou Gu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Insights into DNA Replication without Hydrogen Bonds

(2013) Karin Betz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Catalysts with Tyrosine Kinase Activity

(2013) Shannon M. Walsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Catalysis of a Normally Disfavored RNA Hydrolysis Reaction

(2013) Darren J. Parker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Functional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity

(2013) Aaron E. Engelhart et al.   Nature Chemistry

A thiamin-utilizing ribozyme decarboxylates a pyruvate-like substrate

(2013) Paul Cernak et al.   Nature Chemistry

RNA with iron(II) as a cofactor catalyses electron transfer

(2013) Chiaolong Hsiao et al.   Nature Chemistry

In-ice evolution of RNA polymerase ribozyme activity

(2013) James Attwater et al.   Nature Chemistry

Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation

(2013) Frank R. Bowler et al.   Nature Chemistry

Next-generation sequencing reveals how RNA catalysts evolve from random space

(2013) Sandeep Ameta et al.   NUCLEIC ACIDS RESEARCH

Comprehensive experimental fitness landscape and evolutionary network for small RNA

(2013) J. I. Jimenez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalytic DNA with phosphatase activity

(2013) J. Chandrasekar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonenzymatic Template-Directed RNA Synthesis Inside Model Protocells

(2013) K. Adamala et al.   SCIENCE

From Prelife to Life: How Chemical Kinetics Become Evolutionary Dynamics

(2012) Irene A. Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Natural versus Artificial Creation of Base Pairs in DNA: Origin of Nucleobases from the Perspectives of Unnatural Base Pair Studies

(2012) Ichiro Hirao et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthetic polymers and their potential as genetic materials

(2012) Vitor B. Pinheiro et al.   BIOESSAYS

Liquid crystalline nanostructures: organizing matrices for non-enzymatic nucleic acid polymerization

(2012) David Deamer   CHEMICAL SOCIETY REVIEWS

Synthetic Evolving Systems that Implement a User-Specified Genetic Code of Arbitrary Design

(2012) Jonathan T. Sczepanski et al.   CHEMISTRY & BIOLOGY

The XNA world: progress towards replication and evolution of synthetic genetic polymers

(2012) Vitor B Pinheiro et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

General Acid–Base Catalysis Mediated by Nucleobases in the Hairpin Ribozyme

(2012) Stephanie Kath-Schorr et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cascade of Reduced Speed and Accuracy after Errors in Enzyme-Free Copying of Nucleic Acid Sequences

(2012) Kevin Leu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of N3′-P5′-linked Phosphoramidate DNA by Nonenzymatic Template-Directed Primer Extension

(2012) Shenglong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Spontaneous network formation among cooperative RNA replicators

(2012) Nilesh Vaidya et al.   NATURE

RNA catalysis through compartmentalization

(2012) Christopher A. Strulson et al.   Nature Chemistry

A short adaptive path from DNA to RNA polymerases

(2012) C. Cozens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ubiquitous hammerhead ribozyme

(2012) C. Hammann et al.   RNA

Next-Generation Digital Information Storage in DNA

(2012) G. M. Church et al.   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Lanthanide ions as required cofactors for DNA catalysts

(2012) Victor Dokukin et al.   Chemical Science

Flexizymes: Their Evolutionary History and the Origin of Catalytic Function

(2011) Jumpei Morimoto et al.   ACCOUNTS OF CHEMICAL RESEARCH

Kinetic Consequences of Replacing the Internucleotide Phosphorus Atoms in DNA with Arsenic

(2011) Mostafa I. Fekry et al.   ACS Chemical Biology

Catalysis by the nucleolytic ribozymes

(2011) David M.J. Lilley   BIOCHEMICAL SOCIETY TRANSACTIONS

Catalyzed and Spontaneous Reactions on Ribozyme Ribose

(2011) Rebecca M. Turk et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient enzyme-free copying of all four nucleobases templated by immobilized RNA

(2011) Christopher Deck et al.   Nature Chemistry

Establishing broad generality of DNA catalysts for site-specific hydrolysis of single-stranded DNA

(2011) Ying Xiao et al.   NUCLEIC ACIDS RESEARCH

Ribozyme-Catalyzed Transcription of an Active Ribozyme

(2011) A. Wochner et al.   SCIENCE

Combinatorial Mutation Interference Analysis Reveals Functional Nucleotides Required for DNA Catalysis

(2010) Falk Wachowius et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Expanding Roles for Diverse Physical Phenomena During the Origin of Life

(2010) Itay Budin et al.   Annual Review of Biophysics

A Versatile Endoribonuclease Mimic Made of DNA: Characteristics and Applications of the 8-17 RNA-Cleaving DNAzyme

(2010) Kenny Schlosser  et al.   CHEMBIOCHEM

DNA-catalyzed serine side chain reactivity and selectivity

(2010) Amit Sachdeva et al.   CHEMICAL COMMUNICATIONS

Merely two mutations switch a DNA-hydrolyzing deoxyribozyme from heterobimetallic (Zn2+/Mn2+) to monometallic (Zn2+-only) behavior

(2010) Ying Xiao et al.   CHEMICAL COMMUNICATIONS

An in vitro translation, selection and amplification system for peptide nucleic acids

(2010) Yevgeny Brudno et al.   Nature Chemical Biology

The emerging field of RNA nanotechnology

(2010) Peixuan Guo   Nature Nanotechnology

Improved deoxyribozymes for synthesis of covalently branched DNA and RNA

(2010) Christine S. Lee et al.   NUCLEIC ACIDS RESEARCH

Multiple translational products from a five-nucleotide ribozyme

(2010) R. M. Turk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Construction of Empirical RNA Fitness Landscapes

(2010) J. N. Pitt et al.   SCIENCE

Deoxyribozymes: Selection Design and Serendipity in the Development of DNA Catalysts†

(2009) Scott K. Silverman   ACCOUNTS OF CHEMICAL RESEARCH

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

A Deoxyribozyme, Sero1C, Uses Light and Serotonin to Repair Diverse Pyrimidine Dimers in DNA

(2009) Rebecca E. Thorne et al.   JOURNAL OF MOLECULAR BIOLOGY

Local Rather than Global Folding Enables the Lead-dependent Activity of the 8-17 Deoxyribozyme: Evidence from Contact Photo-crosslinking

(2009) Yong Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

N2′→P3′ Phosphoramidate Glycerol Nucleic Acid as a Potential Alternative Genetic System

(2009) Jesse J. Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peeling the Onion: Ribosomes Are Ancient Molecular Fossils

(2009) C. Hsiao et al.   MOLECULAR BIOLOGY AND EVOLUTION

What recent ribosome structures have revealed about the mechanism of translation

(2009) T. Martin Schmeing et al.   NATURE

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

A hierarchical model for evolution of 23S ribosomal RNA

(2009) Konstantin Bokov et al.   NATURE

Autocatalytic aptazymes enable ligand-dependent exponential amplification of RNA

(2009) Bianca J Lam et al.   NATURE BIOTECHNOLOGY

DNA-catalyzed sequence-specific hydrolysis of DNA

(2009) Madhavaiah Chandra et al.   Nature Chemical Biology

A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M 2+ )

(2009) Marcel Hollenstein et al.   NUCLEIC ACIDS RESEARCH

SITEHOUND-web: a server for ligand binding site identification in protein structures

(2009) M. Hernandez et al.   NUCLEIC ACIDS RESEARCH

The dawn of the RNA World: Toward functional complexity through ligation of random RNA oligomers

(2009) C. Briones et al.   RNA

Widespread Occurrence of Self-Cleaving Ribozymes

(2009) C.-H. T. Webb et al.   SCIENCE

Self-Sustained Replication of an RNA Enzyme

(2009) T. A. Lincoln et al.   SCIENCE

Self-Assembling Sequence-Adaptive Peptide Nucleic Acids

(2009) Yasuyuki Ura et al.   SCIENCE

Systems Chemistry on Ribozyme Self-Construction: Evidence for Anabolic Autocatalysis in a Recombination Network

(2008) Eric J. Hayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

DNA-Catalyzed Formation of Nucleopeptide Linkages

(2008) P. I. Pradeepkumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The origin and evolution of the ribosome

(2008) Temple F Smith et al.   Biology Direct

Metal-ion catalyzed polymerization in the eutectic phase in water–ice: A possible approach to template-directed RNA polymerization

(2008) Pierre-Alain Monnard et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

DNA and RNA Can Be Equally Efficient Catalysts for Carbon−Carbon Bond Formation

(2008) Madhavaiah Chandra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Template-directed synthesis of a genetic polymer in a model protocell

(2008) Sheref S. Mansy et al.   NATURE

Stability of Model Membranes in Extreme Environments

(2008) Trishool Namani et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Thermostability of model protocell membranes

(2008) S. S. Mansy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structure of a Self-Spliced Group II Intron

(2008) N. Toor et al.   SCIENCE