Structure of a yeast spliceosome at 3.6-angstrom resolution

The architecture of the spliceosomal U4/U6.U5 tri-snRNP

(2015) Thi Hoang Duong Nguyen et al.   NATURE

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

(2015) Inessa De et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of pre-mRNA splicing

(2015) Jing Hang et al.   SCIENCE

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

(2015) Inessa De et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition

(2015) Yasushi Kondo et al.   eLife

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

The spliceosome: disorder and dynamics defined

(2014) Weijun Chen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural studies of the spliceosome: zooming into the heart of the machine

(2014) Wojciech P Galej et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Core structure of the U6 small nuclear ribonucleoprotein at 1.7-Å resolution

(2014) Eric J Montemayor et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome

(2014) R. Burns et al.   NEUROLOGY

Endogenous U2{middle dot}U5{middle dot}U6 snRNA complexes in S. pombe are intron lariat spliceosomes

(2014) W. Chen et al.   RNA

Structure of the Yeast Mitochondrial Large Ribosomal Subunit

(2014) A. Amunts et al.   SCIENCE

Beam-induced motion correction for sub-megadalton cryo-EM particles

(2014) Sjors HW Scheres   eLife

Crystal structures of the Lsm complex bound to the 3′ end sequence of U6 small nuclear RNA

(2013) Lijun Zhou et al.   NATURE

Crystal structure of Prp8 reveals active site cavity of the spliceosome

(2013) Wojciech P. Galej et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs

(2013) Jermaine L. Jenkins et al.   NUCLEIC ACIDS RESEARCH

Rearrangements within human spliceosomes captured after exon ligation

(2013) J. O. Ilagan et al.   RNA

Inhibition of RNA Helicase Brr2 by the C-Terminal Tail of the Spliceosomal Protein Prp8

(2013) S. Mozaffari-Jovin et al.   SCIENCE

Structural Basis of Brr2-Prp8 Interactions and Implications for U5 snRNP Biogenesis and the Spliceosome Active Site

(2013) Thi Hoang Duong Nguyen et al.   STRUCTURE

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

Structure, function and regulation of spliceosomal RNA helicases

(2012) Olivier Cordin et al.   CURRENT OPINION IN CELL BIOLOGY

Structure and assembly of the SF3a splicing factor complex of U2 snRNP

(2012) Pei-Chun Lin et al.   EMBO JOURNAL

Saccharomyces cerevisiaeNineTeen Complex (NTC)-associated Factor Bud31/Ycr063w Assembles on Precatalytic Spliceosomes and Improves First and Second Step Pre-mRNA Splicing Efficiency

(2012) Debjani Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Dynamic Protein-Protein Interaction Wiring of the Human Spliceosome

(2012) Anna Hegele et al.   MOLECULAR CELL

CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome

(2012) C. C. Query et al.   RNA

Intrinsic Disorder in the Human Spliceosomal Proteome

(2012) Iga Korneta et al.   PLoS Computational Biology

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

(2011) Adelaine K. W. Leung et al.   NATURE

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Functional organization of the Sm core in the crystal structure of human U1 snRNP

(2010) Gert Weber et al.   EMBO JOURNAL

Molecular Architecture of the Human Prp19/CDC5L Complex

(2010) M. Grote et al.   MOLECULAR AND CELLULAR BIOLOGY

3D Cryo-EM Structure of an Active Step I Spliceosome and Localization of Its Catalytic Core

(2010) Monika M. Golas et al.   MOLECULAR CELL

Characterization of purified human Bact spliceosomal complexes reveals compositional and morphological changes during spliceosome activation and first step catalysis

(2010) S. Bessonov et al.   RNA

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

RNA and Disease

(2009) Thomas A. Cooper et al.   CELL

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Structural mapping of spliceosomes by electron microscopy

(2009) Reinhard Lührmann et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Exon, intron and splice site locations in the spliceosomal B complex

(2009) Elmar Wolf et al.   EMBO JOURNAL

The Evolutionarily Conserved Core Design of the Catalytic Activation Step of the Yeast Spliceosome

(2009) Patrizia Fabrizio et al.   MOLECULAR CELL

Crystal structure of human spliceosomal U1 snRNP at 5.5 Å resolution

(2009) Daniel A. Pomeranz Krummel et al.   NATURE