The structural diversity of artificial genetic polymers

The Expanded Genetic Alphabet

(2015) Denis A. Malyshev et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Xylonucleic acid: synthesis, structure, and orthogonal pairing properties

(2015) Mohitosh Maiti et al.   NUCLEIC ACIDS RESEARCH

High-Resolution Structure of the Eukaryotic 80S Ribosome

(2014) Gulnara Yusupova et al.   Annual Review of Biochemistry

Replicating an Expanded Genetic Alphabet in Cells

(2014) John C. Chaput   CHEMBIOCHEM

A semi-synthetic organism with an expanded genetic alphabet

(2014) Denis A. Malyshev et al.   NATURE

Catalysts from synthetic genetic polymers

(2014) Alexander I. Taylor et al.   NATURE

Insights into RNA structure and function from genome-wide studies

(2014) Stefanie A. Mortimer et al.   NATURE REVIEWS GENETICS

5-Formylcytosine alters the structure of the DNA double helix

(2014) Eun-Ang Raiber et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Towards XNA nanotechnology: new materials from synthetic genetic polymers

(2014) Vitor B. Pinheiro et al.   TRENDS IN BIOTECHNOLOGY

Phosphates in the Z-DNA dodecamer are flexible, but their P-SAD signal is sufficient for structure solution

(2014) Zhipu Luo et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Enantiomeric Selection Properties of β-homoDNA: Enhanced Pairing for Heterochiral Complexes

(2013) Daniele D'Alonzo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Backbone FCH⋅⋅⋅O Hydrogen Bonds in 2′F-Substituted Nucleic Acids

(2013) Nerea Martin-Pintado et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Efficient and Faithful in Vitro Replication System for Threose Nucleic Acid

(2013) Hanyang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of high-affinity DNA aptamers using an expanded genetic alphabet

(2013) Michiko Kimoto et al.   NATURE BIOTECHNOLOGY

Mechanical properties of DNA-like polymers

(2013) Justin P. Peters et al.   NUCLEIC ACIDS RESEARCH

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Solution Structure of a Parallel-Stranded Oligoisoguanine DNA Pentaplex Formed by d(T(iG)4T) in the Presence of Cs+ Ions

(2012) Mijeong Kang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

2′-Fluoro RNA Shows Increased Watson-Crick H-Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data

(2012) Amritraj Patra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Emerging World of Synthetic Genetics

(2012) John C. Chaput et al.   CHEMISTRY & BIOLOGY

Darwinian evolution of an alternative genetic system provides support for TNA as an RNA progenitor

(2012) Hanyang Yu et al.   Nature Chemistry

The solution structure of double helical arabino nucleic acids (ANA and 2′F-ANA): effect of arabinoses in duplex-hairpin interconversion

(2012) Nerea Martín-Pintado et al.   NUCLEIC ACIDS RESEARCH

Structures from Anomalous Diffraction of Native Biological Macromolecules

(2012) Q. Liu et al.   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Unique Gene-Silencing and Structural Properties of 2′-Fluoro-Modified siRNAs

(2011) Muthiah Manoharan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Etiology of Potentially Primordial Biomolecular Structures: From Vitamin B12 to the Nucleic Acids and an Inquiry into the Chemistry of Life’s Origin: A Retrospective

(2011) Albert Eschenmoser   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Evolution of a Bacterium’s Genome

(2011) Philippe Marlière et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Recognition of 2′-Modified Ribonucleoside 5′-Triphosphates: Towards the Evolution of Versatile Aptamers

(2011) Lasse H. Lauridsen et al.   CHEMBIOCHEM

The Crystal Structure of the CeNA:RNA Hybrid ce(GCGTAGCG):r(CGCUACGC)

(2011) Margriet Ovaere et al.   CHEMISTRY-A EUROPEAN JOURNAL

Solution Structure and Conformational Dynamics of Deoxyxylonucleic Acids (dXNA): An Orthogonal Nucleic Acid Candidate

(2011) Mohitosh Maiti et al.   CHEMISTRY-A EUROPEAN JOURNAL

On the Structure and Dynamics of Duplex GNA

(2011) Andrew T. Johnson et al.   JOURNAL OF ORGANIC CHEMISTRY

The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate

(2011) B. H. M. Mooers et al.   RNA

Origins of Specificity in Protein-DNA Recognition

(2010) Remo Rohs et al.   Annual Review of Biochemistry

Oligonucleotides with Sugars Other Than Ribo- and 2′-Deoxyribofuranose in the Backbone: the Solution Structures Determined by NMR in the Context of the ‘Etiology of Nucleic Acids’ Project of Albert Eschenmoser

(2010) Marc-Olivier Ebert et al.   CHEMISTRY & BIODIVERSITY

Crystallographic Studies of Chemically Modified Nucleic Acids: A Backward Glance

(2010) Martin Egli et al.   CHEMISTRY & BIODIVERSITY

The Crystal Structure of Non-Modified and Bipyridine-Modified PNA Duplexes

(2010) Joanne I. Yeh et al.   CHEMISTRY-A EUROPEAN JOURNAL

The many twists and turns of DNA: template, telomere, tool, and target

(2010) Martin Egli et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Energetically Important C−H···F−C Pseudohydrogen Bonding in Water: Evidence and Application to Rational Design of Oligonucleotides with High Binding Affinity

(2010) Maryam Yahyaee Anzahaee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA

(2010) Pradeep S. Pallan et al.   NUCLEIC ACIDS RESEARCH

The crystal structure of an ‘All Locked’ nucleic acid duplex

(2010) André Eichert et al.   NUCLEIC ACIDS RESEARCH

Differential stability of 2′F-ANA•RNA and ANA•RNA hybrid duplexes: roles of structure, pseudohydrogen bonding, hydration, ion uptake and flexibility

(2010) Jonathan K. Watts et al.   NUCLEIC ACIDS RESEARCH

Atomic resolution duplex structure of the simplified nucleic acidGNA

(2009) Mark K. Schlegel et al.   CHEMICAL COMMUNICATIONS

Recent Progress Toward the Templated Synthesis and Directed Evolution of Sequence-Defined Synthetic Polymers

(2009) Yevgeny Brudno et al.   CHEMISTRY & BIOLOGY

Non-natural nucleic acids for synthetic biology

(2009) Daniel H Appella   CURRENT OPINION IN CHEMICAL BIOLOGY

Crystallographic Analysis of a Sex-Specific Enhancer Element: Sequence-Dependent DNA Structure, Hydration, and Dynamics

(2008) Narendra Narayana et al.   JOURNAL OF MOLECULAR BIOLOGY

The Structure of a TNA−TNA Complex in Solution: NMR Study of the Octamer Duplex Derived from α-(l)-Threofuranosyl-(3′-2′)-CGAATTCG

(2008) Marc-Olivier Ebert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Duplex Structure of a Minimal Nucleic Acid

(2008) Mark K. Schlegel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the Fully Modified Left-Handed Cyclohexene Nucleic Acid Sequence GTGTACAC

(2008) Koen Robeyns et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Two Mirror Image 4-Helix Junctions Derived from Glycerol Nucleic Acid

(2008) Richard S. Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solution Structure of a Peptide Nucleic Acid Duplex from NMR Data: Features and Limitations

(2008) Wei He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY