Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
出版年份 2017 全文链接
标题
Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume 16, Issue 11, Pages 755-772
出版商
Springer Nature
发表日期
2017-10-06
DOI
10.1038/nrd.2017.170
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosisex vivo
- (2017) Mareike Lehmann et al. EUROPEAN RESPIRATORY JOURNAL
- Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis
- (2017) Ana L. Mora et al. JOURNAL OF CLINICAL INVESTIGATION
- Idiopathic pulmonary fibrosis
- (2017) Luca Richeldi et al. LANCET
- Mitochondrial DNA Damage Initiates Acute Lung Injury and Multi-Organ System Failure Evoked in Rats by Intra-Tracheal Pseudomonas Aeruginosa
- (2017) Yann-Leei Lee et al. SHOCK
- Cellular senescence mediates fibrotic pulmonary disease
- (2017) Marissa J. Schafer et al. Nature Communications
- Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial
- (2017) Ganesh Raghu et al. Lancet Respiratory Medicine
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
- (2016) Yi Zhu et al. AGING CELL
- Desmoplakin Variants Are Associated with Idiopathic Pulmonary Fibrosis
- (2016) Susan K. Mathai et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Group III Pulmonary Hypertension
- (2016) James R. Klinger CARDIOLOGY CLINICS
- CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism
- (2016) Juliana Camacho-Pereira et al. Cell Metabolism
- Pulmonary Retention of Adipose Stromal Cells following Intravenous Delivery is Markedly Altered in the Presence of ARDS
- (2016) Hongyan Lu et al. CELL TRANSPLANTATION
- Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis
- (2016) I. C. Evans et al. CLINICAL SCIENCE
- FG-3019 anti-connective tissue growth factor monoclonal antibody: results of an open-label clinical trial in idiopathic pulmonary fibrosis
- (2016) Ganesh Raghu et al. EUROPEAN RESPIRATORY JOURNAL
- Recombinant human pentraxin-2 therapy in patients with idiopathic pulmonary fibrosis: safety, pharmacokinetics and exploratory efficacy
- (2016) Bernt van den Blink et al. EUROPEAN RESPIRATORY JOURNAL
- Age-driven developmental drift in the pathogenesis of idiopathic pulmonary fibrosis
- (2016) Moisés Selman et al. EUROPEAN RESPIRATORY JOURNAL
- Keeping the senescence secretome under control: Molecular reins on the senescence-associated secretory phenotype
- (2016) Nicolas Malaquin et al. EXPERIMENTAL GERONTOLOGY
- Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage
- (2016) Seok-Jo Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis
- (2016) Jennifer L. Larson-Casey et al. IMMUNITY
- Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4
- (2016) Travis Lear et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis
- (2016) Kenji Kobayashi et al. JOURNAL OF IMMUNOLOGY
- Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis
- (2016) Chiko Shimbori et al. JOURNAL OF PATHOLOGY
- Epigenetic drug discovery: breaking through the immune barrier
- (2016) David F. Tough et al. NATURE REVIEWS DRUG DISCOVERY
- Targeting the cancer epigenome for therapy
- (2016) Peter A. Jones et al. NATURE REVIEWS GENETICS
- Danazol Treatment for Telomere Diseases
- (2016) Danielle M. Townsley et al. NEW ENGLAND JOURNAL OF MEDICINE
- Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
- (2016) Lluc Mosteiro et al. SCIENCE
- Deciphering the Molecular Signals of PINK1/Parkin Mitophagy
- (2016) Thanh N. Nguyen et al. TRENDS IN CELL BIOLOGY
- Anti-fibrotic effects of valproic acid: role of HDAC inhibition and associated mechanisms
- (2016) Sabbir Khan et al. Epigenomics
- Computational Modeling Predicts Simultaneous Targeting of Fibroblasts and Epithelial Cells Is Necessary for Treatment of Pulmonary Fibrosis
- (2016) Hayley C. Warsinske et al. Frontiers in Pharmacology
- Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats
- (2016) Shan-Shan Rao et al. Journal of Thoracic Disease
- miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis
- (2016) Supparerk Disayabutr et al. PLoS One
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1
- (2015) Meredith L. Sosulski et al. AGING CELL
- Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program
- (2015) Mylène Ferrand et al. Aging-US
- Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients
- (2015) Hagai Yanai et al. Aging-US
- TOLLIP,MUC5B, and the Response toN-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis
- (2015) Justin M. Oldham et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- SFTPA2Mutations in Familial and Sporadic Idiopathic Interstitial Pneumonia
- (2015) Coline H. M. van Moorsel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Exome Sequencing Identifies Mutant TINF2 in a Family With Pulmonary Fibrosis
- (2015) Jonathan K. Alder et al. CHEST
- Phenylbutyric Acid: Simple Structure - Multiple Effects
- (2015) Magdalena Kusaczuk et al. CURRENT PHARMACEUTICAL DESIGN
- Oral immunotherapy with type V collagen in idiopathic pulmonary fibrosis
- (2015) David S. Wilkes et al. EUROPEAN RESPIRATORY JOURNAL
- CC-chemokine ligand 2 inhibition in idiopathic pulmonary fibrosis: a phase 2 trial of carlumab
- (2015) Ganesh Raghu et al. EUROPEAN RESPIRATORY JOURNAL
- HeterozygousRTEL1mutations are associated with familial pulmonary fibrosis
- (2015) Caroline Kannengiesser et al. EUROPEAN RESPIRATORY JOURNAL
- Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors
- (2015) Curt D. Haffner et al. JOURNAL OF MEDICINAL CHEMISTRY
- Valproic acid suppresses collagen by selective regulation of Smads in conjunctival fibrosis
- (2015) Li-Fong Seet et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β
- (2015) Nagalingam R. Sundaresan et al. MOLECULAR AND CELLULAR BIOLOGY
- Gene therapy returns to centre stage
- (2015) Luigi Naldini NATURE
- mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
- (2015) Nicolás Herranz et al. NATURE CELL BIOLOGY
- Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening
- (2015) Bridget D Stuart et al. NATURE GENETICS
- Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
- (2015) Jianhui Chang et al. NATURE MEDICINE
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- (2015) Ming Xu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Telomere dysfunction causes alveolar stem cell failure
- (2015) Jonathan K. Alder et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit
- (2015) I. Das et al. SCIENCE
- Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
- (2015) Martina Korfei et al. THORAX
- Suspension-Expansion of Bone Marrow Results in Small Mesenchymal Stem Cells Exhibiting Increased Transpulmonary Passage Following Intravenous Administration
- (2015) Andrea Zanetti et al. TISSUE ENGINEERING PART C-METHODS
- Phenylbutyric acid inhibits epithelial-mesenchymal transition during bleomycin-induced lung fibrosis
- (2015) Hui Zhao et al. TOXICOLOGY LETTERS
- Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo
- (2015) Caijuan Huan et al. Scientific Reports
- The anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2
- (2015) Li-Hua Dong et al. Scientific Reports
- Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction
- (2015) Juan M. Povedano et al. Cell Reports
- Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis
- (2015) Monika Dadrich et al. OncoImmunology
- Transcription Activator-Like Effector Nuclease (TALEN)-Mediated CLYBL Targeting Enables Enhanced Transgene Expression and One-Step Generation of Dual Reporter Human Induced Pluripotent Stem Cell (iPSC) and Neural Stem Cell (NSC) Lines
- (2015) Trevor Cerbini et al. PLoS One
- Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis
- (2015) Avignat S. Patel et al. PLoS One
- Keratinocyte Growth Factor Promotes Epithelial Survival and Resolution in a Human Model of Lung Injury
- (2014) Murali Shyamsundar et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Revealing the Pathogenic and Aging-related Mechanisms of the Enigmatic Idiopathic Pulmonary Fibrosis. An Integral Model
- (2014) Moisés Selman et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Relationship of DNA Methylation and Gene Expression in Idiopathic Pulmonary Fibrosis
- (2014) Ivana V. Yang et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients
- (2014) Meike H. van der Ree et al. ANTIVIRAL RESEARCH
- Response to androgen therapy in patients with dyskeratosis congenita
- (2014) Payal P. Khincha et al. BRITISH JOURNAL OF HAEMATOLOGY
- A Novel Dyskerin ( DKC1 ) Mutation Is Associated With Familial Interstitial Pneumonia
- (2014) Jonathan A. Kropski et al. CHEST
- MicroRNA mimicry blocks pulmonary fibrosis
- (2014) R. L. Montgomery et al. EMBO Molecular Medicine
- Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice
- (2014) Y. Y. Sanders et al. EUROPEAN RESPIRATORY JOURNAL
- Lung transplantation in telomerase mutation carriers with pulmonary fibrosis
- (2014) L. L. Silhan et al. EUROPEAN RESPIRATORY JOURNAL
- Mitochondria-targeted Ogg1 and Aconitase-2 Prevent Oxidant-induced Mitochondrial DNA Damage in Alveolar Epithelial Cells
- (2014) Seok-Jo Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fibrotic extracellular matrix activates a profibrotic positive feedback loop
- (2014) Matthew W. Parker et al. JOURNAL OF CLINICAL INVESTIGATION
- PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
- (2014) Marta Bueno et al. JOURNAL OF CLINICAL INVESTIGATION
- Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury
- (2014) Andrew E. Vaughan et al. NATURE
- A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis
- (2014) Talmadge E. King et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of Nintedanib in Idiopathic Pulmonary Fibrosis
- (2014) Luca Richeldi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase I Study of GC1008 (Fresolimumab): A Human Anti-Transforming Growth Factor-Beta (TGFβ) Monoclonal Antibody in Patients with Advanced Malignant Melanoma or Renal Cell Carcinoma
- (2014) John C. Morris et al. PLoS One
- A phase 1b study of placenta-derived mesenchymal stromal cells in patients with idiopathic pulmonary fibrosis
- (2014) Daniel C. Chambers et al. RESPIROLOGY
- Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
- (2014) L. Hecker et al. Science Translational Medicine
- The secretome of induced pluripotent stem cells reduces lung fibrosis in part by hepatocyte growth factor
- (2014) Amiq Gazdhar et al. Stem Cell Research & Therapy
- Epigenetic Regulation ofmiR-17∼92Contributes to the Pathogenesis of Pulmonary Fibrosis
- (2013) Duaa Dakhlallah et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- MicroRNA-326 Regulates Profibrotic Functions of Transforming Growth Factor-β in Pulmonary Fibrosis
- (2013) Sudipta Das et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Treatment of Idiopathic Pulmonary Fibrosis With Ambrisentan
- (2013) Ganesh Raghu ANNALS OF INTERNAL MEDICINE
- A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1
- (2013) Nicholas T. Hertz et al. CELL
- Macitentan for the treatment of idiopathic pulmonary fibrosis: the randomised controlled MUSIC trial
- (2013) Ganesh Raghu et al. EUROPEAN RESPIRATORY JOURNAL
- Endoplasmic Reticulum (ER) Stress and Hypoxia Response Pathways Interact to Potentiate Hypoxia-inducible Factor 1 (HIF-1) Transcriptional Activity on Targets Like Vascular Endothelial Growth Factor (VEGF)
- (2013) Ethel R. Pereira et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Coordinated induction of cyclooxygenase-2/prostaglandin E2 and hepatocyte growth factor by apoptotic cells prevents lung fibrosis
- (2013) Young-So Yoon et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Advances in Understanding the Expression and Function of Dipeptidyl Peptidase 8 and 9
- (2013) H. Zhang et al. MOLECULAR CANCER RESEARCH
- Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
- (2013) Tasha E Fingerlin et al. NATURE GENETICS
- Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs
- (2013) Neil C Henderson et al. NATURE MEDICINE
- HGF Expressing Stem Cells in Usual Interstitial Pneumonia Originate from the Bone Marrow and Are Antifibrotic
- (2013) Amiq Gazdhar et al. PLoS One
- Rupatadine Protects against Pulmonary Fibrosis by Attenuating PAF-Mediated Senescence in Rodents
- (2013) Xiao-xi Lv et al. PLoS One
- Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
- (2013) M. A. Nieto SCIENCE
- Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress
- (2013) Y Cheng et al. Cell Death & Disease
- Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts
- (2013) S K Huang et al. Cell Death & Disease
- Metformin improves healthspan and lifespan in mice
- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
- (2013) Imre Noth et al. Lancet Respiratory Medicine
- hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms
- (2012) Allison R. Tsang et al. AGING CELL
- STAT3-Mediated Signaling Dysregulates Lung Fibroblast-Myofibroblast Activation and Differentiation in UIP/IPF
- (2012) Dmitri V. Pechkovsky et al. AMERICAN JOURNAL OF PATHOLOGY
- Hypermethylation-mediated silencing of p14ARF in fibroblasts from idiopathic pulmonary fibrosis
- (2012) José Cisneros et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- A Placebo-Controlled Randomized Trial of Warfarin in Idiopathic Pulmonary Fibrosis
- (2012) Imre Noth et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Role of Endoplasmic Reticulum Stress in Age-Related Susceptibility to Lung Fibrosis
- (2012) Edilson Torres-González et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Telomere elongation and clinical response to androgen treatment in a patient with aplastic anemia and a heterozygous hTERT gene mutation
- (2012) Patrick Ziegler et al. ANNALS OF HEMATOLOGY
- mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis
- (2012) Ramiro Iglesias-Bartolome et al. Cell Stem Cell
- Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
- (2012) Bruno Bernardes de Jesus et al. EMBO Molecular Medicine
- Inhalation treatment of pulmonary fibrosis by liposomal prostaglandin E2
- (2012) Vera Ivanova et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Tollip, an Intracellular Trafficking Protein, Is a Novel Modulator of the Transforming Growth Factor-β Signaling Pathway
- (2012) Lu Zhu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Reactive Oxygen Species Regulate Transforming Growth Factor-β Signaling
- (2012) Manu Jain et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MiR-29 mediates TGFβ1-induced extracellular matrix synthesis through activation of PI3K-AKT pathway in human lung fibroblasts
- (2012) Tao Yang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Treatment of Idiopathic Pulmonary Fibrosis with Losartan: A Pilot Project
- (2012) Marisa Couluris et al. LUNG
- Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates
- (2012) Gregory Hannum et al. MOLECULAR CELL
- miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in Mice
- (2012) Jun Xiao et al. MOLECULAR THERAPY
- Mechanisms of fibrosis: therapeutic translation for fibrotic disease
- (2012) Thomas A Wynn et al. NATURE MEDICINE
- Prednisone, Azathioprine, andN-Acetylcysteine for Pulmonary Fibrosis
- (2012) NEW ENGLAND JOURNAL OF MEDICINE
- A Newfoundland cohort of familial and sporadic idiopathic pulmonary fibrosis patients: clinical and genetic features
- (2012) Bridget A Fernandez et al. RESPIRATORY RESEARCH
- Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism
- (2012) D. Narendra et al. Cold Spring Harbor Perspectives in Biology
- Targeting of XJB-5-131 to Mitochondria Suppresses Oxidative DNA Damage and Motor Decline in a Mouse Model of Huntington’s Disease
- (2012) Zhiyin Xun et al. Cell Reports
- Participation of miR-200 in Pulmonary Fibrosis
- (2011) Shanzhong Yang et al. AMERICAN JOURNAL OF PATHOLOGY
- Prostaglandin E2 protects murine lungs from bleomycin-induced pulmonary fibrosis and lung dysfunction
- (2011) Ryan T. Dackor et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- BUILD-3: A Randomized, Controlled Trial of Bosentan in Idiopathic Pulmonary Fibrosis
- (2011) Talmadge E. King et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Subclinical Lung Disease, Macrocytosis, and Premature Graying in Kindreds With Telomerase ( TERT ) Mutations
- (2011) Alberto Diaz de Leon et al. CHEST
- Specific correction of a splice defect in brain by nutritional supplementation
- (2011) R. S. Shetty et al. HUMAN MOLECULAR GENETICS
- Four faces of cellular senescence
- (2011) Francis Rodier et al. JOURNAL OF CELL BIOLOGY
- A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis
- (2011) Howard Trachtman et al. KIDNEY INTERNATIONAL
- Idiopathic pulmonary fibrosis
- (2011) Talmadge E King et al. LANCET
- Latent TGF-β structure and activation
- (2011) Minlong Shi et al. NATURE
- A CommonMUC5BPromoter Polymorphism and Pulmonary Fibrosis
- (2011) Max A. Seibold et al. NEW ENGLAND JOURNAL OF MEDICINE
- Kinetin Improves IKBKAP mRNA Splicing in Patients With Familial Dysautonomia
- (2011) Felicia B Axelrod et al. PEDIATRIC RESEARCH
- Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
- (2011) J. R. Rock et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intravenous administration of bone marrow mesenchymal stromal cells is safe for the lung in a chronic myocardial infarction model
- (2011) Wei Wang et al. Regenerative Medicine
- Familial pulmonary fibrosis is the strongest risk factor for idiopathic pulmonary fibrosis
- (2011) Cecilia García-Sancho et al. RESPIRATORY MEDICINE
- An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis
- (2011) MONIQUE A. MALOUF et al. RESPIROLOGY
- Epigenetic Regulation of Myofibroblast Differentiation by DNA Methylation
- (2010) Biao Hu et al. AMERICAN JOURNAL OF PATHOLOGY
- FGF-1 reverts epithelial-mesenchymal transition induced by TGF-β1 through MAPK/ERK kinase pathway
- (2010) Carlos Ramos et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
- (2010) Shunsuke Minagawa et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Inhibition and Role of let-7d in Idiopathic Pulmonary Fibrosis
- (2010) Kusum V. Pandit et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Keratinocyte Growth Factor Gene Transduction Ameliorates Pulmonary Fibrosis Induced by Bleomycin in Mice
- (2010) Seiko Sakamoto et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Role of Endoplasmic Reticulum Stress in Epithelial–Mesenchymal Transition of Alveolar Epithelial Cells
- (2010) Qian Zhong et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- AMP-activated Protein Kinase (AMPK) Negatively Regulates Nox4-dependent Activation of p53 and Epithelial Cell Apoptosis in Diabetes
- (2010) Assaad A. Eid et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
- (2010) Gang Liu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease
- (2010) Barry J. Snow et al. MOVEMENT DISORDERS
- Mechanisms of mitophagy
- (2010) Richard J. Youle et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Controlled Trial of Sildenafil in Advanced Idiopathic Pulmonary Fibrosis
- (2010) NEW ENGLAND JOURNAL OF MEDICINE
- Telomere Lengths, Pulmonary Fibrosis and Telomerase (TERT) Mutations
- (2010) Alberto Diaz de Leon et al. PLoS One
- Overexpression of Fibroblast Growth Factor-10 during Both Inflammatory and Fibrotic Phases Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice
- (2009) Varsha V. Gupte et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Imatinib Treatment for Idiopathic Pulmonary Fibrosis
- (2009) Craig E. Daniels et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells
- (2009) R. T. Calado et al. BLOOD
- Effect of interferon gamma-1b on survival in patients with idiopathic pulmonary fibrosis (INSPIRE): a multicentre, randomised, placebo-controlled trial
- (2009) Talmadge E King et al. LANCET
- Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis
- (2009) W. R. Coward et al. MOLECULAR AND CELLULAR BIOLOGY
- Bone Marrow Stem Cells Expressing Keratinocyte Growth Factor via an Inducible Lentivirus Protects against Bleomycin-Induced Pulmonary Fibrosis
- (2009) Susana Aguilar et al. PLoS One
- Genetic Defects in Surfactant Protein A2 Are Associated with Pulmonary Fibrosis and Lung Cancer
- (2008) Yongyu Wang et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection
- (2008) William E. Lawson et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Epithelial Endoplasmic Reticulum Stress and Apoptosis in Sporadic Idiopathic Pulmonary Fibrosis
- (2008) Martina Korfei et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Treatment of Idiopathic Pulmonary Fibrosis with Etanercept
- (2008) Ganesh Raghu et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Telomere Shortening in Familial and Sporadic Pulmonary Fibrosis
- (2008) Jennifer T. Cronkhite et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Thy-1 Promoter Hypermethylation
- (2008) Yan Y. Sanders et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases
- (2008) Ting-Wei Mu et al. CELL
- Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice
- (2008) Sharyn Bayne et al. CELL RESEARCH
- Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis
- (2008) Annika Andersson-Sjöland et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Wound repair and regeneration
- (2008) Geoffrey C. Gurtner et al. NATURE
- Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model
- (2008) H.-L. Feng et al. NEUROSCIENCE
- Partial Restoration of Mutant Enzyme Homeostasis in Three Distinct Lysosomal Storage Disease Cell Lines by Altering Calcium Homeostasis
- (2008) Ting-Wei Mu et al. PLOS BIOLOGY
- Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation
- (2007) Gerald S. Horan et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now