标题
β-Amyloid and the Pathomechanisms of Alzheimer’s Disease: A Comprehensive View
作者
关键词
-
出版物
MOLECULES
Volume 22, Issue 10, Pages 1692
出版商
MDPI AG
发表日期
2017-10-10
DOI
10.3390/molecules22101692
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Aβ propagation and strains: Implications for the phenotypic diversity in Alzheimer's disease
- (2018) Carlo Condello et al. NEUROBIOLOGY OF DISEASE
- Preclinical to phase II amyloid beta (Aβ) peptide modulators under investigation for Alzheimer’s disease
- (2017) Chris G. Parsons et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders
- (2017) Yajin Liao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer’s disease: a rationale for multi-nutrient dementia prevention
- (2017) Marcus O. W. Grimm et al. JOURNAL OF LIPID RESEARCH
- Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease
- (2017) Antero Salminen et al. JOURNAL OF NEUROCHEMISTRY
- Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?
- (2017) Lauren S. Whyte et al. JOURNAL OF NEUROCHEMISTRY
- Drugs in Clinical Trials for Alzheimer's Disease: The Major Trends
- (2017) Sergey O. Bachurin et al. MEDICINAL RESEARCH REVIEWS
- Stop Alzheimer’s before it starts
- (2017) Eric McDade et al. NATURE
- Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes
- (2017) Wei Qiang et al. NATURE
- Not just amyloid: physiological functions of the amyloid precursor protein family
- (2017) Ulrike C. Müller et al. NATURE REVIEWS NEUROSCIENCE
- The blood-brain barrier in Alzheimer's disease
- (2017) Elena Zenaro et al. NEUROBIOLOGY OF DISEASE
- A review on neuroimaging-based classification studies and associated feature extraction methods for Alzheimer's disease and its prodromal stages
- (2017) Saima Rathore et al. NEUROIMAGE
- Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease
- (2017) Reisuke H. Takahashi et al. PATHOLOGY INTERNATIONAL
- Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer’s disease
- (2017) Hassan Bukhari et al. PROGRESS IN NEUROBIOLOGY
- On the path to 2025: understanding the Alzheimer’s disease continuum
- (2017) Paul S. Aisen et al. Alzheimers Research & Therapy
- APP Function and Lipids: A Bidirectional Link
- (2017) Marcus O. W. Grimm et al. Frontiers in Molecular Neuroscience
- APP as a Protective Factor in Acute Neuronal Insults
- (2017) Dimitri Hefter et al. Frontiers in Molecular Neuroscience
- Cellular Regulation of Amyloid Formation in Aging and Disease
- (2017) Esther Stroo et al. Frontiers in Neuroscience
- Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults
- (2017) Mark A. Reger et al. JOURNAL OF ALZHEIMERS DISEASE
- Functional Roles of Amyloid-β Protein Precursor and Amyloid-β Peptides: Evidence from Experimental Studies
- (2017) Mikko Hiltunen et al. JOURNAL OF ALZHEIMERS DISEASE
- Is Alzheimer's Disease a Disorder of Mitochondria-Associated Membranes?
- (2017) Eric A. Schon et al. JOURNAL OF ALZHEIMERS DISEASE
- Diversity of Amyloid-beta Proteoforms in the Alzheimer’s Disease Brain
- (2017) Norelle C. Wildburger et al. Scientific Reports
- Molecular genetics of early-onset Alzheimer's disease revisited
- (2016) Rita Cacace et al. Alzheimers & Dementia
- Enjoy the Trip: Calcium in Mitochondria Back and Forth
- (2016) Diego De Stefani et al. Annual Review of Biochemistry
- Microglial response to LPS increases in wild-type mice during aging but diminishes in an Alzheimer's mouse model: Implication of TLR4 signaling in disease progression
- (2016) Michelle Go et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer’s disease
- (2016) Hwamee Oh et al. BRAIN
- Microglia in Alzheimer’s disease: A multifaceted relationship
- (2016) Ayman ElAli et al. BRAIN BEHAVIOR AND IMMUNITY
- The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained
- (2016) Amit U. Joshi et al. CELL CALCIUM
- AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species
- (2016) Francesco Simone Ruggeri et al. CURRENT PHARMACEUTICAL DESIGN
- Protein Folding and Misfolding, Endoplasmic Reticulum Stress in Neurodegenerative Diseases: in Trace of Novel Drug Targets
- (2016) Botond Penke et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Aging is associated with hypermethylation of autophagy genes in macrophages
- (2016) Hany Khalil et al. Epigenetics
- Neurodegenerative diseases linked to misfolded proteins and their therapeutic approaches: A review
- (2016) Hena Khanam et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: A View of the Regulatory Science Qualification Landscape from the Coalition Against Major Diseases CSF Biomarker Team
- (2016) Stephen P. Arnerić et al. JOURNAL OF ALZHEIMERS DISEASE
- Staging Alzheimer’s Disease Risk by Sequencing Brain Function and Structure, Cerebrospinal Fluid, and Cognition Biomarkers
- (2016) Guangyu Chen et al. JOURNAL OF ALZHEIMERS DISEASE
- Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis
- (2016) Jinghui Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease
- (2016) Kundlik Gadhave et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Inflammasomes link vascular disease with neuroinflammation and brain disorders
- (2016) Nikolett Lénárt et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Walking the tightrope: proteostasis and neurodegenerative disease
- (2016) Justin J. Yerbury et al. JOURNAL OF NEUROCHEMISTRY
- Pathogenic mechanisms of prion protein, amyloid-β and α-synuclein misfolding: the prion concept and neurotoxicity of protein oligomers
- (2016) Cathryn L. Ugalde et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process
- (2016) Giovanna Cenini et al. MOLECULAR BIOLOGY OF THE CELL
- From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery
- (2016) William A. Banks NATURE REVIEWS DRUG DISCOVERY
- Histone H2B monoubiquitination is a critical epigenetic switch for the regulation of autophagy
- (2016) Su Chen et al. NUCLEIC ACIDS RESEARCH
- A transcriptional signature of Alzheimer’s disease is associated with a metastable subproteome at risk for aggregation
- (2016) Prajwal Ciryam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Perspectives for treating Alzheimer's disease: a review on promising pharmacological substances
- (2016) Maurílio de Souza Cazarim et al. Sao Paulo Medical Journal
- Microglia development follows a stepwise program to regulate brain homeostasis
- (2016) O. Matcovitch-Natan et al. SCIENCE
- Complement and microglia mediate early synapse loss in Alzheimer mouse models
- (2016) S. Hong et al. SCIENCE
- There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases
- (2016) Sebastien Paillusson et al. TRENDS IN NEUROSCIENCES
- Drug development in Alzheimer’s disease: the path to 2025
- (2016) Jeffrey Cummings et al. Alzheimers Research & Therapy
- Intracellular Calcium Dysregulation: Implications for Alzheimer’s Disease
- (2016) Simona Magi et al. Biomed Research International
- Genes associated with Alzheimer's disease: an overview and current status
- (2016) Mohan Giri et al. Clinical Interventions in Aging
- A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimers disease
- (2016) R. Freer et al. Science Advances
- The unfolded protein response in neurodegenerative diseases: a neuropathological perspective
- (2015) Wiep Scheper et al. ACTA NEUROPATHOLOGICA
- Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective
- (2015) Matthew Baumgart et al. Alzheimers & Dementia
- Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases
- (2015) William B. Pratt et al. Annual Review of Pharmacology and Toxicology
- Widespread Proteome Remodeling and Aggregation in Aging C. elegans
- (2015) Dirk M. Walther et al. CELL
- Generation and functions of second messengers microdomains
- (2015) Riccardo Filadi et al. CELL CALCIUM
- Dysfunction of Endoplasmic Reticulum (ER) and Mitochondria (MT) in Alzheimer's Disease: The Role of the ER-MT Cross-Talk
- (2015) Katalin Volgyi et al. Current Alzheimer Research
- Cellular Functions of the Amyloid Precursor Protein from Development to Dementia
- (2015) Rik van der Kant et al. DEVELOPMENTAL CELL
- The Chemical Biology of Molecular Chaperones—Implications for Modulation of Proteostasis
- (2015) Kristoffer R. Brandvold et al. JOURNAL OF MOLECULAR BIOLOGY
- Possible involvement of 15-deoxy-Δ12,14-prostaglandin J2in the development of leptin resistance
- (2015) Toru Hosoi et al. JOURNAL OF NEUROCHEMISTRY
- Vascular dysfunction in the pathogenesis of Alzheimer's disease — A review of endothelium-mediated mechanisms and ensuing vicious circles
- (2015) Luigi Yuri Di Marco et al. NEUROBIOLOGY OF DISEASE
- Microglia in Health and Disease
- (2015) Richard M. Ransohoff et al. Cold Spring Harbor Perspectives in Biology
- Impairment of paravascular clearance pathways in the aging brain
- (2014) Benjamin T. Kress et al. ANNALS OF NEUROLOGY
- The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease
- (2014) A.I. Plácido et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Amyloid-β Peptide Induces Mitochondrial Dysfunction by Inhibition of Preprotein Maturation
- (2014) Dirk Mossmann et al. Cell Metabolism
- Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain
- (2014) Jeffrey Blair et al. Current Alzheimer Research
- Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease
- (2014) Edgar Dawkins et al. JOURNAL OF NEUROCHEMISTRY
- Influence ofAPOEgenotype and the presence of Alzheimer's pathology on synaptic membrane lipids of human brains
- (2014) Naoto Oikawa et al. JOURNAL OF NEUROSCIENCE RESEARCH
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Alzheimer’s Disease Genetics: From the Bench to the Clinic
- (2014) Celeste M. Karch et al. NEURON
- Promoting Autophagic Clearance: Viable Therapeutic Targets in Alzheimer’s Disease
- (2014) Lauren G. Friedman et al. Neurotherapeutics
- HSF-1-mediated cytoskeletal integrity determines thermotolerance and life span
- (2014) N. A. Baird et al. SCIENCE
- PICALM modulates autophagy activity and tau accumulation
- (2014) Kevin Moreau et al. Nature Communications
- The role of protein clearance mechanisms in organismal ageing and age-related diseases
- (2014) David Vilchez et al. Nature Communications
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid
- (2014) Joshua HK Tam et al. Molecular Brain
- The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy
- (2013) Patrick L. McGeer et al. ACTA NEUROPATHOLOGICA
- Ca2+-dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid β-treated astrocytes and in a model of Alzheimer's disease
- (2013) Elena Alberdi et al. AGING CELL
- Orchestration of secretory protein folding by ER chaperones
- (2013) Tali Gidalevitz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Proteostasis and neurodegeneration: The roles of proteasomal degradation and autophagy
- (2013) Keiji Tanaka et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The neurobiology of aging and Alzheimer's disease: walking down the same road?
- (2013) Jannic Boehm et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification
- (2013) Devin M. Wolfe et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The amyloid precursor protein: A biochemical enigma in brain development, function and disease
- (2013) Natalia N. Nalivaeva et al. FEBS LETTERS
- The ire-1 ER stress-response pathway is required for normal secretory-protein metabolism in C. elegans
- (2013) M. Safra et al. JOURNAL OF CELL SCIENCE
- Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis
- (2013) W. Gibson Wood et al. JOURNAL OF NEUROCHEMISTRY
- Calcium regulation of neural rhythms, memory and Alzheimer's disease
- (2013) Michael J. Berridge JOURNAL OF PHYSIOLOGY-LONDON
- CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
- (2013) Frederick J Sheedy et al. NATURE IMMUNOLOGY
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- The return of the nucleus: transcriptional and epigenetic control of autophagy
- (2013) Jens Füllgrabe et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models
- (2013) L. Hedskog et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Genetics of Alzheimer Disease
- (2013) R. E. Tanzi Cold Spring Harbor Perspectives in Medicine
- Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease
- (2013) D. M. Holtzman et al. Cold Spring Harbor Perspectives in Medicine
- Spongiform Change in Dementia With Lewy Bodies and Alzheimer Disease
- (2012) Abdullah Sherzai et al. ALZHEIMER DISEASE & ASSOCIATED DISORDERS
- Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease
- (2012) Jesse D. Sengillo et al. BRAIN PATHOLOGY
- Alzheimer culprits: Cellular crossroads and interplay
- (2012) Sylvie Claeysen et al. CELLULAR SIGNALLING
- Intraneuronal β-amyloid and its interactions with proteins and subcellular organelles
- (2012) Botond Penke et al. ELECTROPHORESIS
- Upregulated function of mitochondria-associated ER membranes in Alzheimer disease
- (2012) Estela Area-Gomez et al. EMBO JOURNAL
- Extrusion of misfolded and aggregated proteins - a protective strategy of aging neurons?
- (2012) Jana Doehner et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Intrinsically disordered proteins and novel strategies for drug discovery
- (2012) Vladimir N. Uversky Expert Opinion on Drug Discovery
- Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain
- (2012) Aarti N. Patel et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
- (2012) Konrad Talbot et al. JOURNAL OF CLINICAL INVESTIGATION
- Prion-like spread of protein aggregates in neurodegeneration: Figure 1.
- (2012) Magdalini Polymenidou et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neurotoxicity and Memory Deficits Induced by Soluble Low-Molecular-Weight Amyloid- 1-42 Oligomers Are Revealed In Vivo by Using a Novel Animal Model
- (2012) J. Brouillette et al. JOURNAL OF NEUROSCIENCE
- Spreading of Neurodegenerative Pathology via Neuron-to-Neuron Transmission of -Amyloid
- (2012) S. Nath et al. JOURNAL OF NEUROSCIENCE
- Transgenic Expression of Intraneuronal A 42 But Not A 40 Leads to Cellular A Lesions, Degeneration, and Functional Impairment without Typical Alzheimer's Disease Pathology
- (2012) D. Abramowski et al. JOURNAL OF NEUROSCIENCE
- Endoplasmic reticulum dysfunction in neurological disease
- (2012) Benoit D Roussel et al. LANCET NEUROLOGY
- Genetic insights in Alzheimer's disease
- (2012) Karolien Bettens et al. LANCET NEUROLOGY
- An Interaction Map of Endoplasmic Reticulum Chaperones and Foldases
- (2012) Gregor Jansen et al. MOLECULAR & CELLULAR PROTEOMICS
- Mitochondria-associated ER membranes in Alzheimer disease
- (2012) Eric A. Schon et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
- (2012) Justin M. Nussbaum et al. NATURE
- Prion propagation, toxicity and degradation
- (2012) Adriano Aguzzi et al. NATURE NEUROSCIENCE
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
- (2012) Claudio Hetz NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice
- (2012) Ajeet Rijal Upadhaya et al. NEUROBIOLOGY OF AGING
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- Trans-Synaptic Spread of Tau Pathology In Vivo
- (2012) Li Liu et al. PLoS One
- Is tau ready for admission to the prion club?
- (2012) Garth F. Hall et al. Prion
- Impaired neurotransmission caused by overexpression of -synuclein in nigral dopamine neurons
- (2012) M. Lundblad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purified and synthetic Alzheimer's amyloid beta (A ) prions
- (2012) J. Stohr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease
- (2012) Yunqi Xu et al. PROGRESS IN NEUROBIOLOGY
- Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system
- (2012) Lin Zheng et al. Translational Neurodegeneration
- Should Alzheimer's disease be equated with human brain ageing?: A maladaptive interaction between brain evolution and senescence
- (2011) David Neill AGEING RESEARCH REVIEWS
- Pathogenic protein seeding in alzheimer disease and other neurodegenerative disorders
- (2011) Mathias Jucker et al. ANNALS OF NEUROLOGY
- Amyloid Precursor Protein Processing and Alzheimer's Disease
- (2011) Richard J. O'Brien et al. Annual Review of Neuroscience
- Endoplasmic reticulum stress enhances γ-secretase activity
- (2011) Kazunori Ohta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- α-Synuclein misfolding and Parkinson's disease
- (2011) Leonid Breydo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Suppression of Alzheimer's Disease-Related Phenotypes by Expression of Heat Shock Protein 70 in Mice
- (2011) T. Hoshino et al. JOURNAL OF NEUROSCIENCE
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- Systems biology of Alzheimer's disease: How diverse molecular changes result in memory impairment in AD
- (2011) Gábor Juhász et al. NEUROCHEMISTRY INTERNATIONAL
- The Monomer State of Beta-Amyloid: Where the Alzheimer's Disease Protein Meets Physiology
- (2011) M.L. Giuffrida et al. REVIEWS IN THE NEUROSCIENCES
- Misfolded protein aggregates: Mechanisms, structures and potential for disease transmission
- (2011) Ines Moreno-Gonzalez et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Highly Efficient Protein Misfolding Cyclic Amplification
- (2011) Nuria Gonzalez-Montalban et al. PLoS Pathogens
- Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease
- (2010) Gunnar K. Gouras et al. ACTA NEUROPATHOLOGICA
- Vascular risk factor detection and control may prevent Alzheimer's disease
- (2010) Jack C. de la Torre AGEING RESEARCH REVIEWS
- Ubiquitination in Postsynaptic Function and Plasticity
- (2010) Angela M. Mabb et al. Annual Review of Cell and Developmental Biology
- The cholinergic system in aging and neuronal degeneration
- (2010) Reinhard Schliebs et al. BEHAVIOURAL BRAIN RESEARCH
- Membrane rafts in Alzheimer's disease beta-amyloid production
- (2010) Kulandaivelu S. Vetrivel et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- ABC efflux transporters in brain vasculature of Alzheimer's subjects
- (2010) Hasini C. Wijesuriya et al. BRAIN RESEARCH
- Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
- (2010) César Cárdenas et al. CELL
- Sorting of the Alzheimer's Disease Amyloid Precursor Protein Mediated by the AP-4 Complex
- (2010) Patricia V. Burgos et al. DEVELOPMENTAL CELL
- Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D2concept
- (2010) Vladimir N Uversky Expert Review of Proteomics
- Mysterious oligomerization of the amyloidogenic proteins
- (2010) Vladimir N. Uversky FEBS Journal
- Amyloid oligomers: formation and toxicity of Aβ oligomers
- (2010) Masafumi Sakono et al. FEBS Journal
- Galantamine-induced Amyloid-β Clearance Mediated via Stimulation of Microglial Nicotinic Acetylcholine Receptors
- (2010) Kazuyuki Takata et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amyloid Efflux Transporter Expression at the Blood-Brain Barrier Declines in Normal Aging
- (2010) Gerald D. Silverberg et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A Mouse Model of Amyloid Oligomers: Their Contribution to Synaptic Alteration, Abnormal Tau Phosphorylation, Glial Activation, and Neuronal Loss In Vivo
- (2010) T. Tomiyama et al. JOURNAL OF NEUROSCIENCE
- Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research
- (2010) Asad Jan et al. Nature Protocols
- Prion-like transmission of protein aggregates in neurodegenerative diseases
- (2010) Patrik Brundin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The functional neurophysiology of the amyloid precursor protein (APP) processing pathway
- (2010) A.D. Randall et al. NEUROPHARMACOLOGY
- ADDLs and the signaling web that leads to Alzheimer’s disease
- (2010) Grant A. Krafft et al. NEUROPHARMACOLOGY
- Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines
- (2010) K.J. Lee et al. NEUROSCIENCE
- Regulation of Mammalian Autophagy in Physiology and Pathophysiology
- (2010) Brinda Ravikumar et al. PHYSIOLOGICAL REVIEWS
- Mechanism of amyloid plaque formation suggests an intracellular basis of A pathogenicity
- (2010) R. P. Friedrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The protein kingdom extended: Ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation
- (2010) Konstantin K. Turoverov et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- Peripherally Applied A -Containing Inoculates Induce Cerebral -Amyloidosis
- (2010) Y. S. Eisele et al. SCIENCE
- Intracellular accumulation of amyloid-beta – a predictor for synaptic dysfunction and neuron loss in Alzheimer’s disease
- (2010) Bayer Frontiers in Aging Neuroscience
- Targeting ADAM10 to lipid rafts in neuroblastoma SH-SY5Y cells impairs amyloidogenic processing of the amyloid precursor protein
- (2009) Benjamin Harris et al. BRAIN RESEARCH
- Neuropathology of Lewy body disorders
- (2009) Enikö Kövari et al. BRAIN RESEARCH BULLETIN
- Midlife Serum Cholesterol and Increased Risk of Alzheimer’s and Vascular Dementia Three Decades Later
- (2009) Alina Solomon et al. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The amyloid hypothesis for Alzheimer’s disease: a critical reappraisal
- (2009) John Hardy JOURNAL OF NEUROCHEMISTRY
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids
- (2009) Adriano Aguzzi et al. NEURON
- Induction of cerebral -amyloidosis: Intracerebral versus systemic A inoculation
- (2009) Y. S. Eisele et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MAM: more than just a housekeeper
- (2009) Teruo Hayashi et al. TRENDS IN CELL BIOLOGY
- Amyloid Precursor Protein Trafficking, Processing, and Function
- (2008) Gopal Thinakaran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease
- (2008) B. Boland et al. JOURNAL OF NEUROSCIENCE
- Characterization of the interaction between Aβ 1–42 and glyceraldehyde phosphodehydrogenase
- (2008) Yann Verdier et al. JOURNAL OF PEPTIDE SCIENCE
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- Deregulation of sphingolipid metabolism in Alzheimer's disease
- (2008) Xingxuan He et al. NEUROBIOLOGY OF AGING
- Self-Templated Nucleation in Peptide and Protein Aggregation
- (2008) Stefan Auer et al. PHYSICAL REVIEW LETTERS
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
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