标题
Cellular Regulation of Amyloid Formation in Aging and Disease
作者
关键词
-
出版物
Frontiers in Neuroscience
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-02-14
DOI
10.3389/fnins.2017.00064
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- When proteostasis goes bad: Protein aggregation in the cell
- (2017) Mona Radwan et al. IUBMB LIFE
- Aging and the UPR(ER)
- (2016) Rebecca C. Taylor BRAIN RESEARCH
- Expanding role of molecular chaperones in regulating α-synuclein misfolding; implications in Parkinson’s disease
- (2016) Sandeep K. Sharma et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Liquid–liquid phase separation in cellular signaling systems
- (2016) P Andrew Chong et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Walking the tightrope: proteostasis and neurodegenerative disease
- (2016) Justin J. Yerbury et al. JOURNAL OF NEUROCHEMISTRY
- The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
- (2016) Vaishali Kakkar et al. MOLECULAR CELL
- Mammalian prions and their wider relevance in neurodegenerative diseases
- (2016) John Collinge NATURE
- Amyloid-β pathology and cerebral amyloid angiopathy are frequent in iatrogenic Creutzfeldt-Jakob disease after dural grafting
- (2016) K Frontzek et al. SWISS MEDICAL WEEKLY
- Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy
- (2016) Reinier Oropesa-Nuñez et al. Oncotarget
- The unfolded protein response in neurodegenerative diseases: a neuropathological perspective
- (2015) Wiep Scheper et al. ACTA NEUROPATHOLOGICA
- The Biology of Proteostasis in Aging and Disease
- (2015) Johnathan Labbadia et al. Annual Review of Biochemistry
- Amyloidogenic Oligomerization Transforms Drosophila Orb2 from a Translation Repressor to an Activator
- (2015) Mohammed Repon Khan et al. CELL
- Pumilio1 Haploinsufficiency Leads to SCA1-like Neurodegeneration by Increasing Wild-Type Ataxin1 Levels
- (2015) Vincenzo A. Gennarino et al. CELL
- Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
- (2015) Amandine Molliex et al. CELL
- A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
- (2015) Avinash Patel et al. CELL
- Fibril growth and seeding capacity play key roles in α-synuclein-mediated apoptotic cell death
- (2015) A-L Mahul-Mellier et al. CELL DEATH AND DIFFERENTIATION
- 20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans
- (2015) Niki Chondrogianni et al. FASEB JOURNAL
- Essential role for autophagy in life span extension
- (2015) Frank Madeo et al. JOURNAL OF CLINICAL INVESTIGATION
- Chaperones in Neurodegeneration
- (2015) I. Lindberg et al. JOURNAL OF NEUROSCIENCE
- Human Hsp70 Disaggregase Reverses Parkinson’s-Linked α-Synuclein Amyloid Fibrils
- (2015) Xuechao Gao et al. MOLECULAR CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- The C9orf72 repeat expansion disrupts nucleocytoplasmic transport
- (2015) Ke Zhang et al. NATURE
- Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy
- (2015) Zane Jaunmuktane et al. NATURE
- GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
- (2015) Brian D. Freibaum et al. NATURE
- Proteostasis and aging
- (2015) Susmita Kaushik et al. NATURE MEDICINE
- Persistence of Aβ seeds in APP null mouse brain
- (2015) Lan Ye et al. NATURE NEUROSCIENCE
- Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
- (2015) Ana Jovičić et al. NATURE NEUROSCIENCE
- A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
- (2015) Frances K. Wiseman et al. NATURE REVIEWS NEUROSCIENCE
- The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3
- (2015) Luana Fioriti et al. NEURON
- Review: Modulating the unfolded protein response to prevent neurodegeneration and enhance memory
- (2015) Mark Halliday et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
- (2015) A. C. Woerner et al. SCIENCE
- Increased Aggregation Is More Frequently Associated to Human Disease-Associated Mutations Than to Neutral Polymorphisms
- (2015) Greet De Baets et al. PLoS Computational Biology
- Sorting out the trash: the spatial nature of eukaryotic protein quality control
- (2014) Emily M Sontag et al. CURRENT OPINION IN CELL BIOLOGY
- Barcoding heat shock proteins to human diseases: looking beyond the heat shock response
- (2014) V. Kakkar et al. Disease Models & Mechanisms
- Multistep process of FUS aggregation in the cell cytoplasm involves RNA-dependent and RNA-independent mechanisms
- (2014) Tatyana A. Shelkovnikova et al. HUMAN MOLECULAR GENETICS
- Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
- (2014) Cecilia Månsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prions: Generation and SpreadVersusNeurotoxicity
- (2014) Mark Halliday et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genetic Modulation of Soluble A Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease
- (2014) S. W. Fowler et al. JOURNAL OF NEUROSCIENCE
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
- (2014) Claudio Hetz et al. NATURE REVIEWS NEUROSCIENCE
- Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
- (2014) David W. Sanders et al. NEURON
- The metazoan protein disaggregase and amyloid depolymerase system
- (2014) Mariana P Torrente et al. Prion
- Serial propagation of distinct strains of A prions from Alzheimer's disease patients
- (2014) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease
- (2014) Marc Brehme et al. Cell Reports
- Molecular Chaperone Functions in Protein Folding and Proteostasis
- (2013) Yujin E. Kim et al. Annual Review of Biochemistry
- Prion-like spreading of pathological α-synuclein in brain
- (2013) Masami Masuda-Suzukake et al. BRAIN
- XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity
- (2013) Rebecca C. Taylor et al. CELL
- The Hallmarks of Aging
- (2013) Carlos López-Otín et al. CELL
- Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue
- (2013) Jun-Xia Lu et al. CELL
- Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders
- (2013) Mani Ramaswami et al. CELL
- PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone
- (2013) Sae-Hun Park et al. CELL
- DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios
- (2013) Cecilia Månsson et al. CELL STRESS & CHAPERONES
- Islet Amyloid Polypeptide and Diabetes
- (2013) Gunilla Westermark et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Mechanisms of islet amyloidosis toxicity in type 2 diabetes
- (2013) Andisheh Abedini et al. FEBS LETTERS
- The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides
- (2013) Judith Gillis et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress
- (2013) Stéphanie Escusa-Toret et al. NATURE CELL BIOLOGY
- Unconventional Translation of C9ORF72 GGGGCC Expansion Generates Insoluble Polypeptides Specific to c9FTD/ALS
- (2013) Peter E.A. Ash et al. NEURON
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
- (2013) Ana Griciuc et al. NEURON
- PMEL: a pigment cell-specific model for functional amyloid formation
- (2013) Brenda Watt et al. Pigment Cell & Melanoma Research
- New Insights and Modern Treatment of AL Amyloidosis
- (2013) Chakra P. Chaulagain et al. Current Hematologic Malignancy Reports
- GM1 Cluster Mediates Formation of Toxic Aβ Fibrils by Providing Hydrophobic Environments
- (2012) Saori Fukunaga et al. BIOCHEMISTRY
- Critical Role of Amyloid-like Oligomers of Drosophila Orb2 in the Persistence of Memory
- (2012) Amitabha Majumdar et al. CELL
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies
- (2012) Tina W. Han et al. CELL
- Metazoan Hsp70 machines use Hsp110 to power protein disaggregation
- (2012) Heike Rampelt et al. EMBO JOURNAL
- Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
- (2012) Kelvin C. Luk et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease
- (2012) Anson Pierce et al. JOURNAL OF NEUROCHEMISTRY
- Chaperone networks in protein disaggregation and prion propagation
- (2012) Juliane Winkler et al. JOURNAL OF STRUCTURAL BIOLOGY
- α-Synuclein Oligomers: an Amyloid Pore?
- (2012) Martin T. Stöckl et al. MOLECULAR NEUROBIOLOGY
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Purified and synthetic Alzheimer's amyloid beta (A ) prions
- (2012) J. Stohr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- SERF Protein Is a Direct Modifier of Amyloid Fiber Assembly
- (2012) S. Fabio Falsone et al. Cell Reports
- Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions
- (2011) Heidi Olzscha et al. CELL
- Toxic effects of amyloid fibrils on cell membranes: the importance of ganglioside GM1
- (2011) Monica Bucciantini et al. FASEB JOURNAL
- Hsp42 is required for sequestration of protein aggregates into deposition sites inSaccharomyces cerevisiae
- (2011) Sebastian Specht et al. JOURNAL OF CELL BIOLOGY
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- Prion-like acceleration of a synucleinopathy in a transgenic mouse model
- (2011) Anne-Laure Mougenot et al. NEUROBIOLOGY OF AGING
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD
- (2011) Alan E. Renton et al. NEURON
- The Mammalian Disaggregase Machinery: Hsp110 Synergizes with Hsp70 and Hsp40 to Catalyze Protein Disaggregation and Reactivation in a Cell-Free System
- (2011) James Shorter PLoS One
- Diversity, biogenesis and function of microbial amyloids
- (2011) Luz P. Blanco et al. TRENDS IN MICROBIOLOGY
- Protein homeostasis and aging: The importance of exquisite quality control
- (2010) Hiroshi Koga et al. AGEING RESEARCH REVIEWS
- A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice
- (2010) Anson Pierce et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Identification of MOAG-4/SERF as a Regulator of Age-Related Proteotoxicity
- (2010) Tjakko J. van Ham et al. CELL
- Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
- (2010) C. Rothenberg et al. HUMAN MOLECULAR GENETICS
- Altered Ion Channel Formation by the Parkinson's-Disease-Linked E46K Mutant of α-Synuclein Is Corrected by GM3 but Not by GM1 Gangliosides
- (2010) Eric Di Pasquale et al. JOURNAL OF MOLECULAR BIOLOGY
- A DNAJB Chaperone Subfamily with HDAC-Dependent Activities Suppresses Toxic Protein Aggregation
- (2010) Jurre Hageman et al. MOLECULAR CELL
- A causative link between the structure of aberrant protein oligomers and their toxicity
- (2010) Silvia Campioni et al. Nature Chemical Biology
- Exploring the sequence determinants of amyloid structure using position-specific scoring matrices
- (2010) Sebastian Maurer-Stroh et al. NATURE METHODS
- Cellular strategies for controlling protein aggregation
- (2010) Jens Tyedmers et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Microglia in neurodegenerative disease
- (2010) V. Hugh Perry et al. Nature Reviews Neurology
- Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration
- (2010) Hiroshi Koga et al. NEUROBIOLOGY OF DISEASE
- Reduced IGF-1 Signaling Delays Age-Associated Proteotoxicity in Mice
- (2009) Ehud Cohen et al. CELL
- Converging concepts of protein folding in vitro and in vivo
- (2009) F Ulrich Hartl et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The repeat domain of the melanosome fibril protein Pmel17 forms the amyloid core promoting melanin synthesis
- (2009) R. P. McGlinchey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amyloid- and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
- (2009) V. Rhein et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
- (2009) T. J. Kwiatkowski et al. SCIENCE
- Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules
- (2009) S. K. Maji et al. SCIENCE
- Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity
- (2008) M. L. Duennwald et al. GENES & DEVELOPMENT
- Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
- (2008) R. I. Morimoto GENES & DEVELOPMENT
- Misfolded proteins partition between two distinct quality control compartments
- (2008) Daniel Kaganovich et al. NATURE
- Amyloid formation by globular proteins under native conditions
- (2008) Fabrizio Chiti et al. Nature Chemical Biology
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started