Amyloid β-peptides interfere with mitochondrial preprotein import competence by a coaggregation process

Alzheimer's Disease and the Amyloid-β Peptide

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Interaction of Aβ1–42 Amyloids with Lipids Promotes “Off-Pathway” Oligomerization and Membrane Damage

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Critical analysis of Alzheimer rsquo s amyloid-beta nbsp toxicity to mitochondria

(2015) Yury G. Kaminsky   Frontiers in Bioscience-Landmark

Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-β Amyloidogenesis in Alzheimer Disease

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Three dimensions of the amyloid hypothesis: time, space and 'wingmen'

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Neuropathology and biochemistry of Aβ and its aggregates in Alzheimer’s disease

(2014) Dietmar Rudolf Thal et al.   ACTA NEUROPATHOLOGICA

Amyloid-β Peptide Induces Mitochondrial Dysfunction by Inhibition of Preprotein Maturation

(2014) Dirk Mossmann et al.   Cell Metabolism

Inhibition of mitochondrial protein import by mutant huntingtin

(2014) Hiroko Yano et al.   NATURE NEUROSCIENCE

Truncated and modified amyloid-beta species

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The Alzheimer's disease mitochondrial cascade hypothesis: Progress and perspectives

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Assessing the causes and consequences of co-polymerization in amyloid formation

(2013) Claire J Sarell et al.   Prion

Intraneuronal β-amyloid and its interactions with proteins and subcellular organelles

(2012) Botond Penke et al.   ELECTROPHORESIS

Mitochondrial Protein Synthesis, Import, and Assembly

(2012) Thomas D. Fox   GENETICS

Pink1 Kinase and Its Membrane Potential (Δψ)-dependent Cleavage Product Both Localize to Outer Mitochondrial Membrane by Unique Targeting Mode

(2012) Dorothea Becker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria and Alzheimer's disease

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Intraneuronal Aβ accumulation and neurodegeneration: Lessons from transgenic models

(2012) Oliver Wirths et al.   LIFE SCIENCES

Role of mitochondrial homeostasis and dynamics in Alzheimer's disease

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Large Aggregates Are the Major Soluble Aβ Species in AD Brain Fractionated with Density Gradient Ultracentrifugation

(2012) Dag Sehlin et al.   PLoS One

Amyloid-like Aggregates Sequester Numerous Metastable Proteins with Essential Cellular Functions

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APP processing in Alzheimer's disease

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Intraneuronal β-amyloid accumulation and synapse pathology in Alzheimer’s disease

(2010) Gunnar K. Gouras et al.   ACTA NEUROPATHOLOGICA

Decreased Clearance of CNS  -Amyloid in Alzheimer's Disease

(2010) K. G. Mawuenyega et al.   SCIENCE

Importing Mitochondrial Proteins: Machineries and Mechanisms

(2009) Agnieszka Chacinska et al.   CELL

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

(2008) Alex E. Roher et al.   Alzheimers & Dementia

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON

The amyloid  -peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

(2008) C. A. Hansson Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking, a key player in regulated intramembrane proteolysis

(2008) Ragna Sannerud et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY