A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy
出版年份 2017 全文链接
标题
A3
Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy
作者
关键词
-
出版物
MEDICINAL RESEARCH REVIEWS
Volume 38, Issue 4, Pages 1031-1072
出版商
Wiley
发表日期
2017-07-06
DOI
10.1002/med.21456
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Imidazo[1,2-a]pyrazin-8-amine core for the design of new adenosine receptor antagonists: Structural exploration to target the A3 and A2A subtypes
- (2017) Daniela Poli et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms
- (2017) Jesse Lea Carlin et al. NEUROPHARMACOLOGY
- Structure-Based Screening of Uncharted Chemical Space for Atypical Adenosine Receptor Agonists
- (2016) David Rodríguez et al. ACS Chemical Biology
- Structural refinement of pyrazolo[4,3- d ]pyrimidine derivatives to obtain highly potent and selective antagonists for the human A 3 adenosine receptor
- (2016) Lucia Squarcialupi et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Purine (N)-Methanocarba Nucleoside Derivatives Lacking an Exocyclic Amine as Selective A3 Adenosine Receptor Agonists
- (2016) Dilip K. Tosh et al. JOURNAL OF MEDICINAL CHEMISTRY
- A3 adenosine receptor agonist, CF102, protects against hepatic ischemia/reperfusion injury following partial hepatectomy
- (2016) Gil Ohana et al. Molecular Medicine Reports
- Specific Activation of A3, A2A and A1 Adenosine Receptors in CD73-Knockout Mice Affects B16F10 Melanoma Growth, Neovascularization, Angiogenesis and Macrophage Infiltration
- (2016) Patrycja Koszałka et al. PLoS One
- Adenosine arrests breast cancer cell motility by A3 receptor stimulation
- (2016) Carola Ledderose et al. Purinergic Signalling
- Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?
- (2016) Pier Andrea Borea et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells
- (2016) Angelo Torres et al. Oncotarget
- Metabolic mapping of A3 adenosine receptor agonist MRS5980
- (2015) Zhong-Ze Fang et al. BIOCHEMICAL PHARMACOLOGY
- Understanding allosteric interactions in G protein-coupled receptors using Supervised Molecular Dynamics: A prototype study analysing the human A3 adenosine receptor positive allosteric modulator LUF6000
- (2015) Giuseppe Deganutti et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Hide and seek: a comparative autoradiographic in vitro investigation of the adenosine A3 receptor
- (2015) D. Haeusler et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Pyrazin-2(1H)-ones as a novel class of selective A3 adenosine receptor antagonists
- (2015) Jhonny Azuaje et al. Future Medicinal Chemistry
- 5′-C-Ethyl-tetrazolyl-N6-Substituted Adenosine and 2-Chloro-adenosine Derivatives as Highly Potent Dual Acting A1 Adenosine Receptor Agonists and A3 Adenosine Receptor Antagonists
- (2015) Riccardo Petrelli et al. JOURNAL OF MEDICINAL CHEMISTRY
- One-Pot Reaction To Obtain N,N′-Disubstituted Guanidines of Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine Scaffold as Human A3 Adenosine Receptor Antagonists
- (2015) Pier Giovanni Baraldi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Down-regulation of the A3 adenosine receptor in human mast cells upregulates mediators of angiogenesis and remodeling
- (2015) Noam Rudich et al. MOLECULAR IMMUNOLOGY
- Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist
- (2015) Leigh A. Stoddart et al. NEUROPHARMACOLOGY
- Expression of adenosine receptor subclasses in malignant and adjacent normal human prostate tissues
- (2015) Samira Mousavi et al. PROSTATE
- Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells
- (2015) Iolanda D’Alimonte et al. Purinergic Signalling
- Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors
- (2015) Mohamad Wessam Alnouri et al. Purinergic Signalling
- Anticancer effect of adenosine on gastric cancerviadiverse signaling pathways
- (2015) Ayako Tsuchiya WORLD JOURNAL OF GASTROENTEROLOGY
- Structure-based design, synthesis by click chemistry and in vivo activity of highly selective A3 adenosine receptor agonists
- (2015) Dilip K. Tosh et al. MedChemComm
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- (2015) Stefania Merighi et al. NEOPLASIA
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- (2015) Sarvesh Jajoo et al. NEOPLASIA
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- (2014) Leigh A Stoddart et al. BRITISH JOURNAL OF PHARMACOLOGY
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- (2014) Ana S. Soares et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
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- (2014) Shira Cohen et al. MEDIATORS OF INFLAMMATION
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- (2014) Chi Ting Leung et al. Purinergic Signalling
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- (2013) Monika Sakowicz-Burkiewicz et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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- (2013) Eszter Kozma et al. BIOCHEMICAL PHARMACOLOGY
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- (2013) Fabrizio Vincenzi et al. PLoS One
- Rare coding variants of the adenosine A3 receptor are increased in autism: on the trail of the serotonin transporter regulome
- (2013) Nicholas G Campbell et al. Molecular Autism
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- (2013) György Haskó et al. Frontiers in Immunology
- A3Adenosine Receptor Mediates Apoptosis in 5637 Human Bladder Cancer Cells by GqProtein/PKC-Dependent AIF Upregulation
- (2012) Takeshi Kanno et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
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- (2012) Tai-ichiro Otsuki et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
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- (2012) Yoshitaka Nogi et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
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- (2012) Katia Varani et al. EUROPEAN JOURNAL OF CANCER
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- (2012) Matt Butler et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants
- (2012) Lea Madi et al. EXPERIMENTAL DERMATOLOGY
- Controlling murine and rat chronic pain through A3 adenosine receptor activation
- (2012) Zhoumou Chen et al. FASEB JOURNAL
- Amphiregulin, an Epidermal Growth Factor Receptor Ligand, Plays an Essential Role in the Pathogenesis of Transforming Growth Factor-β-induced Pulmonary Fibrosis
- (2012) Yang Zhou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Water-Soluble Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines as Human A3 Adenosine Receptor Antagonists
- (2012) Pier Giovanni Baraldi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Medicinal Chemistry of A3 Adenosine Receptor Modulators: Pharmacological Activities and Therapeutic Implications
- (2012) Pier Giovanni Baraldi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure-Guided Design of A3 Adenosine Receptor-Selective Nucleosides: Combination of 2-Arylethynyl and Bicyclo[3.1.0]hexane Substitutions
- (2012) Dilip K. Tosh et al. JOURNAL OF MEDICINAL CHEMISTRY
- Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration
- (2012) Keiko Ohsawa et al. JOURNAL OF NEUROCHEMISTRY
- A3 Adenosine Receptor Mediates Apoptosis in In Vitro RCC4-VHL Human Renal Cancer Cells by Up-Regulating AMID Expression
- (2012) Hisao Nagaya et al. JOURNAL OF UROLOGY
- The Adenosine A3 Receptor Agonist Cl-IB-MECA Induces Cell Death Through Ca2+/ROS-Dependent Down Regulation of ERK and Akt in A172 Human Glioma Cells
- (2012) Thae Hyun Kim et al. NEUROCHEMICAL RESEARCH
- The Anti-Tumor Effect of A3 Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells
- (2012) Fabrizio Vincenzi et al. PLoS One
- Adoptive Immunotherapy with Cl-IB-MECA-Treated CD8+ T Cells Reduces Melanoma Growth in Mice
- (2012) Antonella Montinaro et al. PLoS One
- Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?
- (2012) V. Kumar Purinergic Signalling
- Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action
- (2012) Lisa K Stamp et al. ARTHRITIS RESEARCH & THERAPY
- Truncated Nucleosides as A3 Adenosine Receptor Ligands: Combined 2-Arylethynyl and Bicyclohexane Substitutions
- (2012) Dilip K. Tosh et al. ACS Medicinal Chemistry Letters
- Functionally biased modulation of A3 adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers
- (2011) Zhan-Guo Gao et al. BIOCHEMICAL PHARMACOLOGY
- Cl-IB-MECA enhances TNF-α release in peritoneal macrophages stimulated with LPS
- (2011) Giovanni Forte et al. CYTOKINE
- A Nonsynonymous Variant I248L of the Adenosine A3 Receptor Is Associated with Coronary Heart Disease in a Latvian Population
- (2011) Raitis Peculis et al. DNA AND CELL BIOLOGY
- Pharmacological and therapeutic effects of A3 adenosine receptor agonists
- (2011) Pnina Fishman et al. DRUG DISCOVERY TODAY
- Investigational A3adenosine receptor targeting agents
- (2011) Balázs Koscsó et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Adenosine receptor targeting in health and disease
- (2011) Stefania Gessi et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics
- (2011) Lauren T. May et al. FASEB JOURNAL
- Suppression of inflammation response by a novel A3 adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling
- (2011) Hak-Sun Lee et al. IMMUNOBIOLOGY
- Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway
- (2011) Mahmoud Aghaei et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Disparity in FcεRI-Induced Degranulation of Primary Human Lung and Skin Mast Cells Exposed to Adenosine
- (2011) Gregorio Gomez et al. JOURNAL OF CLINICAL IMMUNOLOGY
- New 2-Heterocyclyl-imidazo[2,1-i]purin-5-one Derivatives as Potent and Selective Human A3Adenosine Receptor Antagonists
- (2011) Pier Giovanni Baraldi et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure–Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands
- (2011) Xiyan Hou et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Identification of the 2-Phenylphthalazin-1(2H)-one Scaffold as a New Decorable Core Skeleton for the Design of Potent and Selective Human A3Adenosine Receptor Antagonists
- (2011) Daniela Poli et al. JOURNAL OF MEDICINAL CHEMISTRY
- Treatment of plaque-type psoriasis with oral CF101: data from an exploratory randomized phase 2 clinical trial
- (2011) M. David et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
- (2011) Guillaume Lebon et al. NATURE
- International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update
- (2011) B. B. Fredholm et al. PHARMACOLOGICAL REVIEWS
- Structure of an Agonist-Bound Human A2A Adenosine Receptor
- (2011) F. Xu et al. SCIENCE
- A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release
- (2011) Katia Varani et al. ARTHRITIS RESEARCH & THERAPY
- A3Receptors Are Overexpressed in Pleura from Patients with Mesothelioma and Reduce Cell Growth via Akt/Nuclear Factor-κB Pathway
- (2010) Katia Varani et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors
- (2010) Stefania Gessi et al. BIOCHEMICAL PHARMACOLOGY
- Adenosine receptors and cancer
- (2010) Stefania Gessi et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Recent developments in adenosine receptor ligands and their potential as novel drugs
- (2010) Christa E. Müller et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Functional variability of the adenosine A3 receptor (ADORA3) gene polymorphism in aspirin-induced urticaria
- (2010) S.-H. Kim et al. BRITISH JOURNAL OF DERMATOLOGY
- Control of enteric neuromuscular functions by purinergic A3 receptors in normal rat distal colon and experimental bowel inflammation
- (2010) L Antonioli et al. BRITISH JOURNAL OF PHARMACOLOGY
- Expression and functional role of adenosine receptors in regulating inflammatory responses in human synoviocytes
- (2010) K Varani et al. BRITISH JOURNAL OF PHARMACOLOGY
- A3 Receptor Ligands: Past, Present and Future Trends
- (2010) S. Taliani et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver
- (2010) S. Cohen et al. JOURNAL OF CELLULAR PHYSIOLOGY
- NovelN2-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A3Receptor Antagonists: Inhibition of A3-Mediated Human Glioblastoma Cell Proliferation†
- (2010) Sabrina Taliani et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pyrimidine Derivatives as Potent and Selective A3Adenosine Receptor Antagonists
- (2010) Vicente Yaziji et al. JOURNAL OF MEDICINAL CHEMISTRY
- Adenosine Modulates HIF-1α, VEGF, IL-8, and Foam Cell Formation in a Human Model of Hypoxic Foam Cells
- (2009) Stefania Gessi et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment
- (2009) S. Bar-Yehuda et al. ARTHRITIS AND RHEUMATISM
- Normalization of A2Aand A3adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor α but not methotrexate
- (2009) Katia Varani et al. ARTHRITIS AND RHEUMATISM
- The anti-inflammatory target A3 adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease
- (2009) A. Ochaion et al. CELLULAR IMMUNOLOGY
- Nucleoside Transporter Proteins
- (2009) Miriam Molina-Arcas et al. Current Vascular Pharmacology
- A2A adenosine receptor overexpression and functionality, as well as TNF-α levels, correlate with motor symptoms in Parkinson’s disease
- (2009) Katia Varani et al. FASEB JOURNAL
- Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-κB signalling pathway in thyroid cancer cells
- (2009) Silvana Morello et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Divergent Solution-Phase Synthesis of Diarylpyrimidine Libraries as Selective A3Adenosine Receptor Antagonists
- (2009) Vicente Yaziji et al. JOURNAL OF COMBINATORIAL CHEMISTRY
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- (2009) K. E. Barnholt et al. JOURNAL OF IMMUNOLOGY
- Novel 2- and 4-Substituted 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as Allosteric Modulators of the A3Adenosine Receptor
- (2009) Yoonkyung Kim et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2009) Rosaria Volpini et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2009) Ombretta Lenzi et al. JOURNAL OF MEDICINAL CHEMISTRY
- A Series of 2,4-Disubstituted Quinolines as a New Class of Allosteric Enhancers of the Adenosine A3Receptor
- (2009) Laura H. Heitman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Functionalized Congeners of A3Adenosine Receptor-Selective Nucleosides Containing a Bicyclo[3.1.0]hexane Ring System†
- (2009) Dilip K. Tosh et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and characterization of [76Br]-labeled high-affinity A3 adenosine receptor ligands for positron emission tomography
- (2009) Dale O. Kiesewetter et al. NUCLEAR MEDICINE AND BIOLOGY
- Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000
- (2009) Zhan-Guo Gao et al. BMC Pharmacology & Toxicology
- A3Adenosine Receptor Signaling Influences Pulmonary Inflammation and Fibrosis
- (2008) Eva Morschl et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- The A 3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats
- (2008) A. Ochaion et al. BIOCHEMICAL PHARMACOLOGY
- Structure–activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A3 adenosine receptor antagonists
- (2008) Pier Giovanni Baraldi et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Selective A3 adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system
- (2008) Artem Melman et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Structure–activity relationships of 2-chloro-N6-substituted-4′-thioadenosine-5′-N,N-dialkyluronamides as human A3 adenosine receptor antagonists
- (2008) Lak Shin Jeong et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Activation of the adenosine-A3 receptor stimulates matrix metalloproteinase-9 secretion by macrophages
- (2008) Emilie Velot et al. CARDIOVASCULAR RESEARCH
- Adenosine Receptor Antagonists: Translating Medicinal Chemistry and Pharmacology into Clinical Utility
- (2008) Pier Giovanni Baraldi et al. CHEMICAL REVIEWS
- Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells
- (2008) Xiaoyang Hua et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Ecto-nucleoside Triphosphate Diphosphohydrolase 1 (E-NTPDase1/CD39) Regulates Neutrophil Chemotaxis by Hydrolyzing Released ATP to Adenosine
- (2008) Ross Corriden et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Barbara Cosimelli et al. JOURNAL OF MEDICINAL CHEMISTRY
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- (2008) D. van der Hoeven et al. MOLECULAR PHARMACOLOGY
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- (2008) Zhan-Guo Gao et al. Purinergic Signalling
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- (2007) Stefania Gessi et al. BIOCHEMICAL PHARMACOLOGY
- Selective Human Adenosine A3 Antagonists based on Pyrido[2,1-f]purine-2,4-diones: Novel Features of hA3 Antagonist Binding
- (2007) Eva-María Priego et al. ChemMedChem
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- (2007) K. Varani et al. OSTEOARTHRITIS AND CARTILAGE
- The A3 adenosine receptor: An enigmatic player in cell biology
- (2007) Stefania Gessi et al. PHARMACOLOGY & THERAPEUTICS
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