A3Adenosine Receptor Allosteric Modulator Induces an Anti-Inflammatory Effect:In VivoStudies and Molecular Mechanism of Action

Matrix metalloproteinase-13 expression in IL-1β-treated chondrocytes by activation of the p38 MAPK/c-Fos/AP-1 and JAK/STAT pathways

(2011) Hyun Lim et al.   ARCHIVES OF PHARMACAL RESEARCH

Suppression of inflammation response by a novel A3 adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling

(2011) Hak-Sun Lee et al.   IMMUNOBIOLOGY

Inhibition of experimental auto-immune uveitis by the A3 adenosine receptor agonist CF101

(2011) Pnina Fishman   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Treatment of plaque-type psoriasis with oral CF101: data from an exploratory randomized phase 2 clinical trial

(2011) M. David et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release

(2011) Katia Varani et al.   ARTHRITIS RESEARCH & THERAPY

CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver

(2010) S. Cohen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Treatment of Dry Eye Syndrome with Orally Administered CF101

(2010) Isaac Avni et al.   OPHTHALMOLOGY

Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment

(2009) S. Bar-Yehuda et al.   ARTHRITIS AND RHEUMATISM

The anti-inflammatory target A3 adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn’s disease

(2009) A. Ochaion et al.   CELLULAR IMMUNOLOGY

Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000

(2009) Zhan-Guo Gao et al.   BMC Pharmacology & Toxicology

The A 3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-κB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats

(2008) A. Ochaion et al.   BIOCHEMICAL PHARMACOLOGY